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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
3.
Adiponectin Alleviates Diet-Induced Inflammation in the Liver by Suppressing MCP-1 Expression and Macrophage Infiltration
Jiyoon Ryu, Jason T. Hadley, Zhi Li, Feng Dong, Huan Xu, Xiaoban Xin, Ye Zhang, Cang Chen, Senlin Li, Xiaoning Guo, Jared L. Zhao, Robin J. Leach, Muhammad A. Abdul-Ghani, Ralph A. DeFronzo, Amrita Kamat, Feng Liu, Lily Q. Dong
Diabetes. 2021 Jun; 70(6): 1303–1316. Published online 2021 Mar 18. doi: 10.2337/db20-1073
PMCID:
PMC8275886
AbstractArticlePDF–1.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic β-cells
Baile Wang, Huige Lin, Xiaomu Li, Wenqi Lu, Jae Bum Kim, Aimin Xu, Kenneth K. Y. Cheng
Proc Natl Acad Sci U S A. 2020 Nov 10; 117(45): 28307–28315. Published online 2020 Oct 29. doi: 10.1073/pnas.2016997117
PMCID:
PMC7668165
AbstractArticlePDF–1.7M
6.
APPL2 Negatively Regulates Olfactory Functions by Switching Fate Commitments of Neural Stem Cells in Adult Olfactory Bulb via Interaction with Notch1 Signaling
Chong Gao, Tingting Yan, Xingmiao Chen, Kenneth K. Y. Cheng, Aimin Xu, Jiangang Shen
Neurosci Bull. 2020 Sep; 36(9): 997–1008. Published online 2020 May 28. doi: 10.1007/s12264-020-00514-6
PMCID:
PMC7475139
AbstractArticlePDF–2.2M
7.
The sperm associated antigen 6 interactome and its role in spermatogenesis
Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang
Reproduction. Author manuscript; available in PMC 2020 Jul 18.
Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522
PMCID:
PMC7368494
AbstractArticlePDF–1.8M
8.
A trans-eQTL network regulates osteoclast multinucleation and bone mass
Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras
eLife. 2020; 9: e55549. Published online 2020 Jun 19. doi: 10.7554/eLife.55549
PMCID:
PMC7351491
AbstractArticlePDF–5.1M
9.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
Activation of hypothalamic RIP‐Cre neurons promotes beiging of WAT via sympathetic nervous system
Baile Wang, Ang Li, Xiaomu Li, Philip WL Ho, Donghai Wu, Xiaoqi Wang, Zhuohao Liu, Kelvin KL Wu, Sonata SY Yau, Aimin Xu, Kenneth KY Cheng
EMBO Rep. 2018 Apr; 19(4): e44977. Published online 2018 Feb 21. doi: 10.15252/embr.201744977
PMCID:
PMC5891405
AbstractArticlePDF–3.6M
12.
The LMO2 oncogene regulates DNA replication in hematopoietic cells
Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang
Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113
PMCID:
PMC4747768
AbstractArticlePDF–1.0M
13.
Appl1 and Appl2 are Expendable for Mouse Development but are Essential for HGF-induced Akt Activation and Migration in Mouse Embryonic Fibroblasts
Yinfei Tan, Xiaoban Xin, Francis J. Coffey, David L. Wiest, Lily Q. Dong, Joseph R. Testa
J Cell Physiol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: J Cell Physiol. 2016 May; 231(5): 1142–1150. Published online 2015 Oct 21. doi: 10.1002/jcp.25211
PMCID:
PMC4728037
AbstractArticlePDF–1.6M
14.
Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages
Jeremy C. Yeo, Adam A. Wall, Lin Luo, Jennifer L. Stow
Mol Biol Cell. 2015 Mar 1; 26(5): 952–965. doi: 10.1091/mbc.E14-10-1457
PMCID:
PMC4342030
AbstractArticlePDF–7.3M
15.
Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway
Liufeng Mao, Wanhua Lin, Tao Nie, Xiaoyan Hui, Xuefei Gao, Kuai Li, Mengxiao Ding, Xiaofeng Tang, Peng Li, Yu Wang, Aimin Xu, Pentao Liu, Donghai Wu
Cell Biosci. 2014; 4: 60. Published online 2014 Oct 2. doi: 10.1186/2045-3701-4-60
PMCID:
PMC4201708
AbstractArticlePDF–2.5M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Appl1 is Dispensable for Akt Signaling in vivo and Mouse T Cell Development
Yinfei Tan, Huihong You, Francis J. Coffey, David L. Wiest, Joseph R. Testa
Genesis. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: Genesis. 2010 Sep; 48(9): 531–539. doi: 10.1002/dvg.20657
PMCID:
PMC2944914
AbstractArticlePDF–1.9M
20.
Appl1 Is Dispensable for Mouse Development, and Loss of Appl1 Has Growth Factor-selective Effects on Akt Signaling in Murine Embryonic Fibroblasts
Yinfei Tan, Huihong You, Chao Wu, Deborah A. Altomare, Joseph R. Testa
J Biol Chem. 2010 Feb 26; 285(9): 6377–6389. Published online 2009 Dec 29. doi: 10.1074/jbc.M109.068452
PMCID:
PMC2825433
AbstractArticlePDF–6.3M

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