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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis
Kevin R. Zhang, Bailey Baumann, Ying Song, Jacob Sterling, Elizabeth A. Erler, Samyuktha Guttha, Zbynek Kozmik, Joshua L. Dunaief
Exp Eye Res. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Exp Eye Res. 2022 May; 218: 109028. Published online 2022 Mar 8. doi: 10.1016/j.exer.2022.109028
PMCID:
PMC9050911
AbstractArticlePDF–2.0M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter
Katrin Schulz, Chris D. Vulpe, Leah Z. Harris, Samuel David
J Neurosci. 2011 Sep 14; 31(37): 13301–13311. doi: 10.1523/JNEUROSCI.2838-11.2011
PMCID:
PMC6623272
AbstractArticlePDF–5.2M
5.
Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes
Zheng Chen, Ruiwei Jiang, Mengxia Chen, Jiashuo Zheng, Min Chen, Nady Braidy, Shunli Liu, Guohao Liu, Zaitunamu Maimaitiming, Tianqi Shen, Joshua L. Dunaief, Christopher D. Vulpe, Gregory J. Anderson, Huijun Chen
Sci Rep. 2019; 9: 9437. Published online 2019 Jul 1. doi: 10.1038/s41598-019-46019-9
PMCID:
PMC6603037
AbstractArticlePDF–2.4M
6.
Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin
Brie K. Fuqua, Yan Lu, David M. Frazer, Deepak Darshan, Sarah J. Wilkins, Linda Dunn, Alex V. Loguinov, Scott C. Kogan, Pavle Matak, Huijun Chen, Joshua L. Dunaief, Chris D. Vulpe, Gregory J. Anderson
Cell Mol Gastroenterol Hepatol. 2018; 6(4): 405–427. Published online 2018 Jun 23. doi: 10.1016/j.jcmgh.2018.06.006
PMCID:
PMC6120670
AbstractArticlePDF–7.7M
7.
Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux
Min Chen, Jiashuo Zheng, Guohao Liu, En Xu, Junzhuo Wang, Brie K. Fuqua, Chris D. Vulpe, Gregory J. Anderson, Huijun Chen
Redox Biol. 2018 Jul; 17: 432–439. Published online 2018 May 31. doi: 10.1016/j.redox.2018.05.013
PMCID:
PMC6007082
AbstractArticlePDF–2.8M
8.
Iron promotes oxidative cell death caused by bisretinoids of retina
Keiko Ueda, Hye Jin Kim, Jin Zhao, Ying Song, Joshua L. Dunaief, Janet R. Sparrow
Proc Natl Acad Sci U S A. 2018 May 8; 115(19): 4963–4968. Published online 2018 Apr 23. doi: 10.1073/pnas.1722601115
PMCID:
PMC5948992
AbstractArticlePDF–1.1M
9.
Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels
Jacob Sterling, Samyuktha Guttha, Ying Song, Delu Song, Majda Hadziahmetovic, Joshua L. Dunaief
Exp Eye Res. Author manuscript; available in PMC 2018 Feb 1.
Published in final edited form as: Exp Eye Res. 2017 Feb; 155: 15–23. Published online 2017 Jan 3. doi: 10.1016/j.exer.2016.12.008
PMCID:
PMC5359041
AbstractArticlePDF–1.4M
10.
Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney
Bo Jiang, Guohao Liu, Jiashuo Zheng, Mengxia Chen, Zaitunamu Maimaitiming, Min Chen, Shunli Liu, Ruiwei Jiang, Brie K. Fuqua, Joshua L. Dunaief, Chris D. Vulpe, Gregory J. Anderson, Hongwei Wang, Huijun Chen
Sci Rep. 2016; 6: 39470. Published online 2016 Dec 19. doi: 10.1038/srep39470
PMCID:
PMC5171654
AbstractArticlePDF–2.8M
11.
Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone
Liangliang Zhao, Majda Hadziahmetovic, Chenguang Wang, Xueying Xu, Ying Song, H.A. Jinnah, Jolanta Wodzinska, Jared Iacovelli, Natalie Wolkow, Predrag Krajacic, Alyssa Cwanger Weissberger, John Connelly, Michael Spino, Michael K. Lee, James Connor, Benoit Giasson, Z. Leah Harris, Joshua L. Dunaief
J Neurochem. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: J Neurochem. 2015 Dec; 135(5): 958–974. Published online 2015 Sep 29. doi: 10.1111/jnc.13292
PMCID:
PMC4943332
AbstractArticlePDF–2.2M
12.
Mice with hepcidin-resistant ferroportin accumulate iron in the retina
Milan Theurl, Delu Song, Esther Clark, Jacob Sterling, Steve Grieco, Sandro Altamura, Bruno Galy, Matthias Hentze, Martina U. Muckenthaler, Joshua L. Dunaief
FASEB J. 2016 Feb; 30(2): 813–823. Published online 2015 Oct 27. doi: 10.1096/fj.15-276758
PMCID:
PMC4714557
AbstractArticle
13.
The Oral Iron Chelator Deferiprone Protects against Iron Overload–Induced Retinal Degeneration
Majda Hadziahmetovic, Ying Song, Natalie Wolkow, Jared Iacovelli, Steven Grieco, Jennifer Lee, Arkady Lyubarsky, Domenico Pratico, John Connelly, Michael Spino, Z. Leah Harris, Joshua L. Dunaief
Invest Ophthalmol Vis Sci. 2011 Feb; 52(2): 959–968. Published online 2011 Feb 16. doi: 10.1167/iovs.10-6207
PMCID:
PMC4183363
AbstractArticlePDF–2.1M
14.
The Multicopper Ferroxidase Hephaestin Enhances Intestinal Iron Absorption in Mice
Brie K. Fuqua, Yan Lu, Deepak Darshan, David M. Frazer, Sarah J. Wilkins, Natalie Wolkow, Austin G. Bell, JoAnn Hsu, Catherine C. Yu, Huijun Chen, Joshua L. Dunaief, Gregory J. Anderson, Chris D. Vulpe
PLoS One. 2014; 9(6): e98792. Published online 2014 Jun 4. doi: 10.1371/journal.pone.0098792
PMCID:
PMC4045767
AbstractArticlePDF–5.4M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Ferroxidase Hephaestin's Cell-Autonomous Role in the Retinal Pigment Epithelium
Natalie Wolkow, Delu Song, Ying Song, Sally Chu, Majda Hadziahmetovic, Jennifer C. Lee, Jared Iacovelli, Steven Grieco, Joshua L. Dunaief
Am J Pathol. 2012 Apr; 180(4): 1614–1624. doi: 10.1016/j.ajpath.2011.12.041
PMCID:
PMC3349827
AbstractArticlePDF–3.7M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Generation of Cre Transgenic Mice with Postnatal RPE-Specific Ocular Expression
Jared Iacovelli, Chen Zhao, Natalie Wolkow, Peter Veldman, Kandace Gollomp, Pallavi Ojha, Nina Lukinova, Ayala King, Leonard Feiner, Noriko Esumi, Donald J. Zack, Eric A. Pierce, Douglas Vollrath, Joshua L. Dunaief
Invest Ophthalmol Vis Sci. 2011 Mar; 52(3): 1378–1383. Published online 2011 Mar 14. doi: 10.1167/iovs.10-6347
PMCID:
PMC3101664
AbstractArticlePDF–1.3M
19.
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
Hiroki Kaneko, Sami Dridi, Valeria Tarallo, Bradley D. Gelfand, Benjamin J. Fowler, Won Gil Cho, Mark E. Kleinman, Steven L. Ponicsan, William W. Hauswirth, Vince A. Chiodo, Katalin Karikó, Jae Wook Yoo, Dong-ki Lee, Majda Hadziahmetovic, Ying Song, Smita Misra, Gautam Chaudhuri, Frank W. Buaas, Robert E. Braun, David R. Hinton, Qing Zhang, Hans E. Grossniklaus, Jan M. Provis, Michele C. Madigan, Ann H. Milam, Nikki L. Justice, Romulo J.C. Albuquerque, Alexander D. Blandford, Sasha Bogdanovich, Yoshio Hirano, Jassir Witta, Elaine Fuchs, Dan R. Littman, Balamurali K. Ambati, Charles M. Rudin, Mark M.W. Chong, Patrick Provost, Jennifer F. Kugel, James A. Goodrich, Joshua L. Dunaief, Judit Z. Baffi, Jayakrishna Ambati
Nature. Author manuscript; available in PMC 2011 Sep 17.
Published in final edited form as: Nature. 2011 Mar 17; 471(7338): 325–330. Published online 2011 Feb 6. doi: 10.1038/nature09830
PMCID:
PMC3077055
AbstractArticlePDF–3.2M
20.
Age-Dependent Retinal Iron Accumulation and Degeneration in Hepcidin Knockout Mice
Majda Hadziahmetovic, Ying Song, Padmavathi Ponnuru, Jared Iacovelli, Allan Hunter, Nadine Haddad, John Beard, James R. Connor, Sophie Vaulont, Joshua L. Dunaief
Invest Ophthalmol Vis Sci. 2011 Jan; 52(1): 109–118. Published online 2011 Jan 5. doi: 10.1167/iovs.10-6113
PMCID:
PMC3053271
AbstractArticlePDF–3.4M

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