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Items: 1 to 20 of 42

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse
Tessa R. Sanders, Matthew W. Kelley
Proc Natl Acad Sci U S A. 2022 Nov 29; 119(48): e2203935119. Published online 2022 Nov 21. doi: 10.1073/pnas.2203935119
PMCID:
PMC9860252
AbstractArticlePDF–11M
3.
Tbx2 is a master regulator of inner versus outer hair cell differentiation
Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan
Nature. Author manuscript; available in PMC 2022 Dec 30.
Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3
PMCID:
PMC9803360
AbstractArticlePDF–4.3M
4.
Espin overexpression causes stereocilia defects and provides an anti‐capping effect on actin polymerization
Lili Zheng, Stephen A. Adam, Jaime García‐Anoveros, Brian J. Mitchell, James R. Bartles
Cytoskeleton (Hoboken) 2022 Jun-Aug; 79(6-8): 64–74. Published online 2022 Jul 30. doi: 10.1002/cm.21719
PMCID:
PMC9796729
AbstractArticlePDF–11M
5.
Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme
Morag A. Lewis, Neil J. Ingham, Jing Chen, Selina Pearson, Francesca Di Domenico, Sohinder Rekhi, Rochelle Allen, Matthew Drake, Annelore Willaert, Victoria Rook, Johanna Pass, Thomas Keane, David J. Adams, Abigail S. Tucker, Jacqueline K. White, Karen P. Steel
BMC Biol. 2022; 20: 67. Published online 2022 Mar 17. doi: 10.1186/s12915-022-01257-8
PMCID:
PMC8928630
AbstractArticlePDF–27M
6.
Norrie disease protein is essential for cochlear hair cell maturation
Yushi Hayashi, Hao Chiang, ChunJie Tian, Artur A. Indzhykulian, Albert S. B. Edge
Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2106369118. Published online 2021 Sep 20. doi: 10.1073/pnas.2106369118
PMCID:
PMC8488680
AbstractArticlePDF–3.2M
7.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
8.
Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin
Nga Chu Lui, Wing Yip Tam, Caiji Gao, Jian-Dong Huang, Chi Chiu Wang, Liwen Jiang, Wing Ho Yung, Kin Ming Kwan
Nat Commun. 2017; 8: 15079. Published online 2017 May 18. doi: 10.1038/ncomms15079
PMCID:
PMC5454373
AbstractArticlePDF–5.2M
9.
Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear
Andrew Forge, Ruth R. Taylor, Sally J. Dawson, Michael Lovett, Daniel J. Jagger
PLoS Genet. 2017 Mar; 13(3): e1006692. Published online 2017 Mar 27. doi: 10.1371/journal.pgen.1006692
PMCID:
PMC5386298
AbstractArticlePDF–6.5M
10.
Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Seham Ebrahim, Matthew R. Avenarius, M’hamed Grati, Jocelyn F. Krey, Alanna M. Windsor, Aurea D. Sousa, Angela Ballesteros, Runjia Cui, Bryan A. Millis, Felipe T. Salles, Michelle A. Baird, Michael W. Davidson, Sherri M. Jones, Dongseok Choi, Lijin Dong, Manmeet H. Raval, Christopher M. Yengo, Peter G. Barr-Gillespie, Bechara Kachar
Nat Commun. 2016; 7: 10833. Published online 2016 Mar 1. doi: 10.1038/ncomms10833
Correction in:
Nat Commun. 2017; 8: 16133.
PMCID:
PMC4773517
AbstractArticlePDF–8.2M
11.
Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth
Andrea Lelli, Vincent Michel, Jacques Boutet de Monvel, Matteo Cortese, Montserrat Bosch-Grau, Asadollah Aghaie, Isabelle Perfettini, Typhaine Dupont, Paul Avan, Aziz El-Amraoui, Christine Petit
J Cell Biol. 2016 Jan 18; 212(2): 231–244. doi: 10.1083/jcb.201509017
PMCID:
PMC4738386
AbstractArticlePDF–3.2M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
KATNAL1 Regulation of Sertoli Cell Microtubule Dynamics Is Essential for Spermiogenesis and Male Fertility
Lee B. Smith, Laura Milne, Nancy Nelson, Sharon Eddie, Pamela Brown, Nina Atanassova, Moira K. O'Bryan, Liza O'Donnell, Danielle Rhodes, Sara Wells, Diane Napper, Patrick Nolan, Zuzanna Lalanne, Michael Cheeseman, Josephine Peters
PLoS Genet. 2012 May; 8(5): e1002697. Published online 2012 May 24. doi: 10.1371/journal.pgen.1002697
PMCID:
PMC3359976
AbstractArticlePDF–7.7M
14.
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions
Raymond C. Merritt, Uri Manor, Felipe T. Salles, M’hamed Grati, Andrea C. Dose, William C. Unrath, Omar A. Quintero, Christopher M. Yengo, Bechara Kachar
Curr Biol. Author manuscript; available in PMC 2013 Feb 21.
Published in final edited form as: Curr Biol. 2012 Feb 21; 22(4): 320–325. Published online 2012 Jan 19. doi: 10.1016/j.cub.2011.12.053
PMCID:
PMC3288355
AbstractArticlePDF–1.9M
15.
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins
Céline Revenu, Florent Ubelmann, Ilse Hurbain, Fatima El-Marjou, Florent Dingli, Damarys Loew, Delphine Delacour, Jules Gilet, Edith Brot-Laroche, Francisco Rivero, Daniel Louvard, Sylvie Robine
Mol Biol Cell. 2012 Jan 15; 23(2): 324–336. doi: 10.1091/mbc.E11-09-0765
PMCID:
PMC3258176
AbstractArticlePDF–9.2M
16.
Genetic Analyses of the Mouse Deafness Mutations Varitint-Waddler (Va) and Jerker (Espnje)
Hung J. Kim, Torrance Jackson, Konrad Noben–Trauth
J Assoc Res Otolaryngol. 2003 Feb; 4(1): 83–90. Published online 2002 Sep 18. doi: 10.1007/s10162-002-3011-0
PMCID:
PMC3202448
SummaryPDF–227K
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Polycystin-1 Is Required for Stereocilia Structure But Not for Mechanotransduction in Inner Ear Hair Cells
Katherine A. Steigelman, Andrea Lelli, Xudong Wu, Jiangang Gao, Susan Lin, Klaus Piontek, Claas Wodarczyk, Alessandra Boletta, Hyunho Kim, Feng Qian, Gregory Germino, Gwenaëlle S. G. Géléoc, Jeffrey R. Holt, Jian Zuo
J Neurosci. 2011 Aug 24; 31(34): 12241–12250. doi: 10.1523/JNEUROSCI.6531-10.2011
PMCID:
PMC3164988
AbstractArticlePDF–2.4M
19.
Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice
Gabriella Sekerková, Claus-Peter Richter, James R. Bartles
PLoS Genet. 2011 Mar; 7(3): e1002032. Published online 2011 Mar 24. doi: 10.1371/journal.pgen.1002032
PMCID:
PMC3063760
AbstractArticlePDF–8.6M
20.
Targeting of the Hair Cell Proteins Cadherin 23, Harmonin, Myosin XVa, Espin, and Prestin in an Epithelial Cell Model
Lili Zheng, Jing Zheng, Donna S. Whitlon, Jaime García-Añoveros, James R. Bartles
J Neurosci. 2010 May 26; 30(21): 7187–7201. doi: 10.1523/JNEUROSCI.0852-10.2010
PMCID:
PMC2989820
AbstractArticlePDF–4.5M

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