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Select item 111409071.

Knockout mice with pituitary malformations help identify human cases of hypopituitarism

Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis

Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y

PMCID:: PMC11140907

Abstract Article PDF–4.4M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104042863.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 100959354.

Differential roles of BAF and PBAF subunits, Arid1b and Arid2, in MLL-AF9 leukemogenesis

Theresa Bluemn, Jesse Schmitz, Yongwei Zheng, Robert Burns, Shikan Zheng, Joshua DeJong, Luke Christiansen, Olivia Arnold, Jesus Izaguirre-Carbonell, Demin Wang, Aniruddha J Deshpande, Nan Zhu

Leukemia. Author manuscript; available in PMC 2023 Apr 12.

Published in final edited form as: Leukemia. 2022 Apr; 36(4): 946–955. Published online 2022 Jan 12. doi: 10.1038/s41375-021-01505-w

PMCID:: PMC10095935

Abstract Article PDF–1.8M

Select item 100418805.

Arid2 regulates HSC differentiation in normal hematopoiesis

Theresa Bluemn, Jesse Schmitz, Yuhong Chen, Yongwei Zheng, Yongguang Zhang, Shikan Zheng, Robert Burns, Joshua DeJong, Luke Christiansen, Jesus Izaguirre-Carbonell, Demin Wang, Nan Zhu

Exp Hematol. Author manuscript; available in PMC 2023 Mar 27.

Published in final edited form as: Exp Hematol. 2021 Feb; 94: 37–46. Published online 2020 Dec 17. doi: 10.1016/j.exphem.2020.12.004

PMCID:: PMC10041880

Abstract Article PDF–1.5M

Select item 99504796.

ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2

Hui-Jun Cao, Hao Jiang, Kai Ding, Xiao-Song Qiu, Ning Ma, Feng-Kun Zhang, Yi-Kang Wang, Qian-Wen Zheng, Ji Xia, Qian-Zhi Ni, Sheng Xu, Bing Zhu, Xu-Fen Ding, Tian-Wei Chen, Lin Qiu, Wei Chen, Zhi-Gang Li, Bin Zhou, Wen-Ming Feng, Dong Xie, Jing-Jing Li

Cell Death Differ. 2023 Feb; 30(2): 383–396. Published online 2022 Nov 17. doi: 10.1038/s41418-022-01090-0

PMCID:: PMC9950479

Abstract Article PDF–7.6M

Select item 95737857.

PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse

Rodrigo O. de Castro, Luciana Previato de Almeida, Agustin Carbajal, Irma Gryniuk, Roberto J. Pezza

Development. 2022 Sep 15; 149(18): dev199967. Published online 2022 Sep 16. doi: 10.1242/dev.199967

PMCID:: PMC9573785

Abstract Article

Select item 94819338.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 88505839.

Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development

Vanessa Polanetzki, Franziska Fröb, Tina Baroti, Margit Schimmel, Ernst R. Tamm, Michael Wegner

Sci Rep. 2022; 12: 2651. Published online 2022 Feb 16. doi: 10.1038/s41598-022-06588-8

PMCID:: PMC8850583

Abstract Article PDF–4.4M

Select item 858983710.

Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males

Debashish U. Menon, Oleksandr Kirsanov, Christopher B. Geyer, Terry Magnuson

Nat Commun. 2021; 12: 6581. Published online 2021 Nov 12. doi: 10.1038/s41467-021-26828-1

PMCID:: PMC8589837

Abstract Article PDF–5.9M

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 810230812.

SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies.

Mahesh Saqcena, Luis Javier Leandro-Garcia, Jesper L. V. Maag, Vatche Tchekmedyian, Gnana P. Krishnamoorthy, Prasanna P. Tamarapu, Vera Tiedje, Vincent Reuter, Jeffrey A. Knauf, Elisa de Stanchina, Bin Xu, Xiao-Hui Liao, Samuel Refetoff, Ronald Ghossein, Ping Chi, Alan L. Ho, Richard P. Koche, James A. Fagin

Cancer Discov. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Cancer Discov. 2021 May; 11(5): 1158–1175. Published online 2020 Dec 14. doi: 10.1158/2159-8290.CD-20-0735

PMCID:: PMC8102308

Abstract Article PDF–2.9M

Select item 761068013.

ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer

Thaidy Moreno, Beatriz Monterde, Laura González-Silva, Isabel Betancor-Fernández, Carlos Revilla, Antonio Agraz-Doblas, Javier Freire, Pablo Isidro, Laura Quevedo, Rosa Blanco, Santiago Montes-Moreno, Laura Cereceda, Aurora Astudillo, Berta Casar, Piero Crespo, Cristina Morales Torres, Paola Scaffidi, Javier Gomez-Roman, Eduardo Salido, Ignacio Varela

Oncogene. Author manuscript; available in PMC 2021 Apr 24.

Published in final edited form as: Oncogene. 2021 Apr 1; 40(16): 2923–2935. Published online 2021 Mar 19. doi: 10.1038/s41388-021-01748-y

PMCID:: PMC7610680

Abstract Article PDF–1.8M

Select item 752001414.

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation

Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman

Dev Biol. Author manuscript; available in PMC 2020 Sep 27.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008

PMCID:: PMC7520014

Abstract Article PDF–2.6M

Select item 706068115.

Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis

Hao Jiang, Hui-Jun Cao, Ning Ma, Wen-Dai Bao, Jing-Jing Wang, Tian-Wei Chen, Er-Bin Zhang, Yan-Mei Yuan, Qian-Zhi Ni, Feng-Kun Zhang, Xu-Fen Ding, Qian-Wen Zheng, Yi-Kang Wang, Min Zhu, Xiang Wang, Jing Feng, Xue-Li Zhang, Shu-Qun Cheng, Dan-Jun Ma, Lin Qiu, Jing-Jing Li, Dong Xie

Proc Natl Acad Sci U S A. 2020 Mar 3; 117(9): 4770–4780. Published online 2020 Feb 18. doi: 10.1073/pnas.1914937117

PMCID:: PMC7060681

Abstract Article PDF–3.2M

Select item 645951016.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 611389017.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner

Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571

PMCID:: PMC6113890

Abstract Article PDF–4.8M

Select item 609412518.

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation

Jian Sima, Zhijiang Yan, Yaohui Chen, Elin Lehrmann, Yongqing Zhang, Ramaiah Nagaraja, Weidong Wang, Zhong Wang, David Schlessinger

Proc Natl Acad Sci U S A. 2018 Aug 7; 115(32): 8173–8178. Published online 2018 Jul 23. doi: 10.1073/pnas.1800930115

PMCID:: PMC6094125

Abstract Article PDF–1.5M

Select item 582831419.

The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

Lulu Liu, Xiaoling Wan, Peipei Zhou, Xiaoyuan Zhou, Wei Zhang, Xinhui Hui, Xiujie Yuan, Xiaodan Ding, Ruihong Zhu, Guangxun Meng, Hui Xiao, Feng Ma, He Huang, Xianmin Song, Bin Zhou, Sidong Xiong, Yan Zhang

J Hematol Oncol. 2018; 11: 27. Published online 2018 Feb 26. doi: 10.1186/s13045-018-0567-7

PMCID:: PMC5828314

Abstract Article PDF–3.0M

Select item 538259120.

A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)

Stefan H. Geyer, Lukas Reissig, Julia Rose, Robert Wilson, Fabrice Prin, Dorota Szumska, Ramiro Ramirez‐Solis, Catherine Tudor, Jacqui White, Timothy J. Mohun, Wolfgang J. Weninger

J Anat. 2017 May; 230(5): 710–719. Published online 2017 Feb 9. doi: 10.1111/joa.12590

PMCID:: PMC5382591

Abstract Article PDF–1.5M

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