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Select item 108731961.

NELF and PAF1C complexes are core transcriptional machineries controlling colon cancer stemness

Koji Aoki, Akari Nitta, Ayumi Igarashi

Oncogene. 2024; 43(8): 566–577. Published online 2024 Jan 5. doi: 10.1038/s41388-023-02930-0

PMCID:: PMC10873196

Abstract Article PDF–8.0M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91063033.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 81917784.

NSMF promotes the replication stress-induced DNA damage response for genome maintenance

Min Kyung Ju, Kyeong Jin Shin, Joo Rak Lee, Keon Woo Khim, Eun A. Lee, Jae Sun Ra, Byung-Gyu Kim, Han-seul Jo, Jong Hyuk Yoon, Tae Moon Kim, Kyungjae Myung, Jang Hyun Choi, Hongtae Kim, Young Chan Chae

Nucleic Acids Res. 2021 Jun 4; 49(10): 5605–5622. Published online 2021 May 8. doi: 10.1093/nar/gkab311

PMCID:: PMC8191778

Abstract Article PDF–7.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70330217.

IL-1 transcriptional responses to LPS are regulated by a complex of RNA-binding proteins

Lihua Shi, Li Song, Kelly Maurer, Ying Dou, Vishesh R. Patel, Chun Su, Michelle E. Leonard, Sumei Lu, Kenyaita M. Hodge, Annabel Torres, Alessandra Chesi, Struan F.A. Grant, Andrew D. Wells, Zhe Zhang, Michelle A. Petri, Kathleen E. Sullivan

J Immunol. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: J Immunol. 2020 Mar 1; 204(5): 1334–1344. Published online 2020 Jan 17. doi: 10.4049/jimmunol.1900650

PMCID:: PMC7033021

Abstract Article PDF–1.0M

Select item 67632428.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Abstract Article PDF–12M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 393068410.

Differential Expression of Nasal Embryonic LHRH Factor (NELF) Variants in Immortalized GnRH Neuronal Cell Lines

Samuel D. Quaynor, Lindsey Y. Goldberg, Eun Kyung Ko, Robert K. Stanley, Durkadin Demir, Hyung-Goo Kim, Lynn P. Chorich, Richard S. Cameron, Lawrence C. Layman

Mol Cell Endocrinol. Author manuscript; available in PMC 2015 Mar 5.

Published in final edited form as: Mol Cell Endocrinol. 2014 Mar 5; 383(0): 32–37. Published online 2013 Dec 4. doi: 10.1016/j.mce.2013.11.020

PMCID:: PMC3930684

Abstract Article PDF–737K

Select item 388881811.

Nasal Embryonic LHRH Factor (NELF) Mutations in Patients with Normosmic Hypogonadotropic Hypogonadism and Kallmann Syndrome

Ning Xu, Hyung-Goo Kim, Balasubramanian Bhagavath, Sung-Gyu Cho, Jae Ho Lee, Kyungsoo Ha, Irene Meliciani, Wolfgang Wenzel, Robert H. Podolsky, Lynn P. Chorich, Kathryn A. Stackhouse, Anna M.H. Grove, Lawrence N. Odom, Metin Ozata, David P. Bick, Richard J. Sherins, Soo-Hyun Kim, Richard S. Cameron, Lawrence C. Layman

Fertil Steril. Author manuscript; available in PMC 2014 Jan 12.

Published in final edited form as: Fertil Steril. 2011 Apr; 95(5): 1613–20.e1-7. Published online 2011 Feb 15. doi: 10.1016/j.fertnstert.2011.01.010

PMCID:: PMC3888818

Abstract Article PDF–289K

Select item 376480412.

Negative Elongation Factor (NELF) Coordinates RNA Polymerase II Pausing, Premature Termination, and Chromatin Remodeling to Regulate HIV Transcription

Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David. S. Gilmour, Andrew J. Henderson

J Biol Chem. 2013 Sep 6; 288(36): 25995–26003. Published online 2013 Jul 24. doi: 10.1074/jbc.M113.496489

PMCID:: PMC3764804

Abstract Article PDF–903K

Select item 343799213.

NELF Is a Nuclear Protein Involved in Hypothalamic GnRH Neuronal Migration

Ning Xu, Balasubramanian Bhagavath, Hyung-Goo Kim, Lisa Halvorson, Robert S. Podolsky, Lynn P. Chorich, Puttur Prasad, Wen-Cheng Xiong, Richard S. Cameron, Lawrence C. Layman

Mol Cell Endocrinol. Author manuscript; available in PMC 2012 Sep 10.

Published in final edited form as: Mol Cell Endocrinol. 2010 May 5; 319(1-2): 47–55. Published online 2009 Dec 16. doi: 10.1016/j.mce.2009.11.016

PMCID:: PMC3437992

Abstract Article PDF–1.2M

Select item 343148114.

Discovery of hundreds of mirtrons in mouse and human small RNA data

Erik Ladewig, Katsutomo Okamura, Alex S. Flynt, Jakub O. Westholm, Eric C. Lai

Genome Res. 2012 Sep; 22(9): 1634–1645. doi: 10.1101/gr.133553.111

PMCID:: PMC3431481

Abstract Article PDF–4.8M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 273408116.

DNA sequence and analysis of human chromosome 9

S. J. Humphray, K. Oliver, A. R. Hunt, R. W. Plumb, J. E. Loveland, K. L. Howe, T. D. Andrews, S. Searle, S. E. Hunt, C. E. Scott, M. C. Jones, R. Ainscough, J. P. Almeida, K. D. Ambrose, R. I. S. Ashwell, A. K. Babbage, S. Babbage, C. L. Bagguley, J. Bailey, R. Banerjee, D. J. Barker, K. F. Barlow, K. Bates, H. Beasley, O. Beasley, C. P. Bird, S. Bray-Allen, A. J. Brown, J. Y. Brown, D. Burford, W. Burrill, J. Burton, C. Carder, N. P. Carter, J. C. Chapman, Y. Chen, G. Clarke, S. Y. Clark, C. M. Clee, S. Clegg, R. E. Collier, N. Corby, M. Crosier, A. T. Cummings, J. Davies, P. Dhami, M. Dunn, I. Dutta, L. W. Dyer, M. E. Earthrowl, L. Faulkner, C. J. Fleming, A. Frankish, J. A. Frankland, L. French, D. G. Fricker, P. Garner, J. Garnett, J. Ghori, J. G. R. Gilbert, C. Glison, D. V. Grafham, S. Gribble, C. Griffiths, S. Griffiths-Jones, R. Grocock, J. Guy, R. E. Hall, S. Hammond, J. L. Harley, E. S. I. Harrison, E. A. Hart, P. D. Heath, C. D. Henderson, B. L. Hopkins, P. J. Howard, P. J. Howden, E. Huckle, C. Johnson, D. Johnson, A. A. Joy, M. Kay, S. Keenan, J. K. Kershaw, A. M. Kimberley, A. King, A. Knights, G. K. Laird, C. Langford, S. Lawlor, D. A. Leongamornlert, M. Leversha, C. Lloyd, D. M. Lloyd, J. Lovell, S. Martin, M. Mashreghi-Mohammadi, L. Matthews, S. McLaren, K. E. McLay, A. McMurray, S. Milne, T. Nickerson, J. Nisbett, G. Nordsiek, A. V. Pearce, A. I. Peck, K. M. Porter, R. Pandian, S. Pelan, B. Phillimore, S. Povey, Y. Ramsey, V. Rand, M. Scharfe, H. K. Sehra, R. Shownkeen, S. K. Sims, C. D. Skuce, M. Smith, C. A. Steward, D. Swarbreck, N. Sycamore, J. Tester, A. Thorpe, A. Tracey, A. Tromans, D. W. Thomas, M. Wall, J. M. Wallis, A. P. West, S. L. Whitehead, D. L. Willey, S. A. Williams, L. Wilming, P. W. Wray, L. Young, J. L. Ashurst, A. Coulson, H. Blöcker, R. Durbin, J. E. Sulston, T. Hubbard, M. J. Jackson, D. R. Bentley, S. Beck, J. Rogers, I. Dunham

Nature. Author manuscript; available in PMC 2009 Aug 28.

Published in final edited form as: Nature. 2004 May 27; 429(6990): 369–374. doi: 10.1038/nature02465