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Select item 115160671.

Genome‐Wide Association Analysis Identifies LILRB2 Gene for Pathological Myopia

Lingxi Jiang, Lulin Huang, Chao Dai, Rui Zheng, Masahiro Miyake, Yuki Mori, Shin‐ya Nakao, Kazuya Morino, Kenji Ymashiro, Yang‐Bao Miao, Qi Li, Weiming Ren, Zimeng Ye, Hongjing Li, Zhenglin Yang, Yi Shi

Adv Sci (Weinh) 2024 Oct; 11(40): 2308968. Published online 2024 Aug 29. doi: 10.1002/advs.202308968

PMCID:: PMC11516067

Abstract Article PDF–5.1M

Select item 104101002.

Soluble LILRA3 is aberrantly expressed in antiphospholipid syndrome (APS) and is a potential marker of thrombotic APS

Hongjiang Liu, Chun Li, Hui Shi, Yixue Guo, Yundi Tang, Chen Chen, Zhen Zhao, Claire K Hoy, Srilakshmi Yalavarthi, Gabriel Figueroa-Parra, Ali Duarte-Garcia, Yu Zuo, Zhanguo Li, Jason S Knight, Jianping Guo

Rheumatology (Oxford) 2022 Dec; 61(12): 4962–4974. Published online 2022 Mar 24. doi: 10.1093/rheumatology/keac192

PMCID:: PMC10410100

Abstract Article PDF–731K

Select item 103631203.

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis

Dan-Pei Li, Li Huang, Ran-Ran Kan, Xiao-Yu Meng, Shu-Yun Wang, Hua-Jie Zou, Ya-Ming Guo, Pei-Qiong Luo, Li-Meng Pan, Yu-Xi Xiang, Bei-Bei Mao, Yu-Yu Xie, Zhi-Han Wang, Min Yang, Rui He, Yan Yang, Zhe-Long Liu, Jun-Hui Xie, De-Lin Ma, Ben-Ping Zhang, Shi-Ying Shao, Xi Chen, Si-Miao Xu, Wen-Tao He, Wen-Jun Li, Yong Chen, Xue-Feng Yu

Nat Commun. 2023; 14: 4436. Published online 2023 Jul 22. doi: 10.1038/s41467-023-40183-3

PMCID:: PMC10363120

Abstract Article PDF–8.3M

Select item 100741604.

Immunoglobulin‑like receptors and the generation of innate immune memory

Mouhamad Al-Moussawy, Hossam A. Abdelsamed, Fadi G. Lakkis

Immunogenetics. Author manuscript; available in PMC 2023 Apr 5.

Published in final edited form as: Immunogenetics. 2022 Feb; 74(1): 179–195. Published online 2022 Jan 16. doi: 10.1007/s00251-021-01240-7

PMCID:: PMC10074160

Abstract Article PDF–752K

Select item 93265095.

Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy

Celia Dechavanne, Odilon Nouatin, Rafiou Adamou, Sofie Edslev, Anita Hansen, Florian Meurisse, Ibrahim Sadissou, Erasme Gbaguidi, Jacqueline Milet, Gilles Cottrell, Laure Gineau, Audrey Sabbagh, Achille Massougbodji, Kabirou Moutairou, Eduardo A. Donadi, Edgardo D. Carosella, Philippe Moreau, Ed Remarque, Michael Theisen, Nathalie Rouas-Freiss, André Garcia, Benoit Favier, David Courtin

Front Immunol. 2022; 13: 909831. Published online 2022 Jul 12. doi: 10.3389/fimmu.2022.909831

PMCID:: PMC9326509

Abstract Article PDF–2.9M

Select item 92295936.

Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis

Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, Shu-Hsia Chen, Chinnaswamy Jagannath

Front Immunol. 2022; 13: 865503. Published online 2022 Jun 10. doi: 10.3389/fimmu.2022.865503

PMCID:: PMC9229593

Abstract Article PDF–5.5M

Select item 92063877.

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

Mol Neurodegener. 2022; 17: 44. Published online 2022 Jun 18. doi: 10.1186/s13024-022-00550-y

PMCID:: PMC9206387

Abstract Article PDF–11M

Select item 86173738.

Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2

Yunqing Gu, Jun Cao, Xinyu Zhang, Hai Gao, Yuyan Wang, Jia Wang, Juan He, Xiaoyi Jiang, Jinlan Zhang, Guanghui Shen, Jie Yang, Xichen Zheng, Gaowei Hu, Yuanfei Zhu, Shujuan Du, Yunkai Zhu, Rong Zhang, Jianqing Xu, Fei Lan, Di Qu, Guoliang Xu, Yun Zhao, Dong Gao, Youhua Xie, Min Luo, Zhigang Lu

Cell Res. 2022 Jan; 32(1): 24–37. Published online 2021 Nov 26. doi: 10.1038/s41422-021-00595-6

Correction in:: Cell Res. 2022 Jun; 32(6): 600.

PMCID:: PMC8617373

Abstract Article PDF–5.7M

Select item 82520619.

Association of the Leukocyte Immunoglobulin‐like Receptor A3 Gene With Neutrophil Activation and Disease Susceptibility in Adult‐Onset Still’s Disease

Mengyan Wang, Mengru Liu, Jinchao Jia, Hui Shi, Jialin Teng, Honglei Liu, Yue Sun, Xiaobing Cheng, Junna Ye, Yutong Su, Huihui Chi, Tingting Liu, Zhihong Wang, Liyan Wan, Jianfen Meng, Yuning Ma, Chengde Yang, Qiongyi Hu

Arthritis Rheumatol. 2021 Jun; 73(6): 1033–1043. Published online 2021 May 2. doi: 10.1002/art.41635

PMCID:: PMC8252061

Abstract Article PDF–947K

Select item 824951810.

A susceptibility locus in the IL12B but not LILRA3 region is associated with vascular damage in Takayasu arteritis

Keiichiro Kadoba, Ryu Watanabe, Takeshi Iwasaki, Toshiki Nakajima, Koji Kitagori, Shuji Akizuki, Kosaku Murakami, Ran Nakashima, Motomu Hashimoto, Masao Tanaka, Koichiro Ohmura, Akio Morinobu, Chikashi Terao, Hajime Yoshifuji

Sci Rep. 2021; 11: 13667. Published online 2021 Jul 1. doi: 10.1038/s41598-021-93213-9

PMCID:: PMC8249518

Abstract Article PDF–1.2M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 815560112.

Prognostic Significance of Immune Checkpoints HLA-G/ILT-2/4 and PD-L1 in Colorectal Cancer

Qiong-Yuan Chen, Yu-Xin Chen, Qiu-Yue Han, Jiang-Gang Zhang, Wen-Jun Zhou, Xia Zhang, Yao-Han Ye, Wei-Hua Yan, Aifen Lin

Front Immunol. 2021; 12: 679090. Published online 2021 May 13. doi: 10.3389/fimmu.2021.679090

PMCID:: PMC8155601

Abstract Article PDF–2.5M

Select item 792980513.

Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

Aiqin Gao, Xia Liu, Wenli Lin, Jingnan Wang, Shuyun Wang, Fusheng Si, Lan Huang, Yangjing Zhao, Yuping Sun, Guangyong Peng

J Immunother Cancer. 2021; 9(3): e001536. Published online 2021 Mar 2. doi: 10.1136/jitc-2020-001536

PMCID:: PMC7929805

Abstract Article PDF–7.7M

Select item 784766614.

ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation

Xiaozheng Chen, Aiqin Gao, Fang Zhang, Zijiang Yang, Shuyun Wang, Yuying Fang, Juan Li, Jingnan Wang, Wenjing Shi, Linlin Wang, Yan Zheng, Yuping Sun

Theranostics. 2021; 11(7): 3392–3416. Published online 2021 Jan 19. doi: 10.7150/thno.52435

PMCID:: PMC7847666

Abstract Article PDF–5.1M

Select item 780641915.

Leukocyte immunoglobulin‐like receptor A3 is increased in IBD patients and functions as an anti‐inflammatory modulator

X. Lan, F. Liu, J. Ma, Y. Chang, X. Lan, L. Xiang, X. Shen, F. Zhou, Q. Zhao

Clin Exp Immunol. 2021 Feb; 203(2): 286–303. Published online 2020 Nov 12. doi: 10.1111/cei.13529

PMCID:: PMC7806419

Abstract Article PDF–1.9M

Select item 733341116.

The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma

Marcela García, Maria Belen Palma, Jerome Verine, Santiago Miriuka, Ana M. Inda, Ana L. Errecalde, François Desgrandchamps, Edgardo D. Carosella, Diana Tronik-Le Roux

BMC Cancer. 2020; 20: 624. Published online 2020 Jul 3. doi: 10.1186/s12885-020-07113-8

PMCID:: PMC7333411

Abstract Article PDF–2.4M

Select item 724793817.

The Interaction of LILRB2 with HLA-B is Associated with Psoriasis Susceptibility

Rebecca L. Yanovsky, Haoyan Chen, Stephen Leslie, Mary Carrington, Wilson Liao

J Invest Dermatol. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: J Invest Dermatol. 2020 Jun; 140(6): 1292–1295.e3. Published online 2019 Dec 24. doi: 10.1016/j.jid.2019.12.006

PMCID:: PMC7247938

Article PDF–57K

Select item 652194018.

Immunoglobulin-like transcript 4 and human leukocyte antigen-G interaction promotes the progression of human colorectal cancer

Zhaoyang Cai, Lu Wang, Yali Han, Wenwen Gao, Xiaojuan Wei, Rumei Gong, Mingliang Zhu, Yuping Sun, Shuwen Yu

Int J Oncol. 2019 Jun; 54(6): 1943–1954. Published online 2019 Mar 22. doi: 10.3892/ijo.2019.4761

PMCID:: PMC6521940

Abstract Article PDF–2.0M

Select item 630495519.

Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis

Chikashi Terao, Hajime Yoshifuji, Takayoshi Matsumura, Taeko K. Naruse, Tomonori Ishii, Yoshikazu Nakaoka, Yohei Kirino, Keitaro Matsuo, Tomoki Origuchi, Masakazu Shimizu, Yasuhiro Maejima, Eisuke Amiya, Natsuko Tamura, Takahisa Kawaguchi, Meiko Takahashi, Kazuya Setoh, Koichiro Ohmura, Ryu Watanabe, Tetsuya Horita, Tatsuya Atsumi, Mitsuru Matsukura, Tetsuro Miyata, Yuta Kochi, Toshio Suda, Kazuo Tanemoto, Akira Meguro, Yukinori Okada, Akiyoshi Ogimoto, Motohisa Yamamoto, Hiroki Takahashi, Shingo Nakayamada, Kazuyoshi Saito, Masataka Kuwana, Nobuhisa Mizuki, Yasuharu Tabara, Atsuhisa Ueda, Issei Komuro, Akinori Kimura, Mitsuaki Isobe, Tsuneyo Mimori, Fumihiko Matsuda

Proc Natl Acad Sci U S A. 2018 Dec 18; 115(51): 13045–13050. Published online 2018 Nov 29. doi: 10.1073/pnas.1808850115

PMCID:: PMC6304955

Abstract Article PDF–772K

Select item 594826620.

The impact of HLA-G, LILRB1 and LILRB2 gene polymorphisms on susceptibility to and severity of endometriosis

Aleksandra Bylińska, Karolina Wilczyńska, Jacek Malejczyk, Łukasz Milewski, Marta Wagner, Monika Jasek, Wanda Niepiekło-Miniewska, Andrzej Wiśniewski, Rafał Płoski, Ewa Barcz, Piotr Roszkowski, Paweł Kamiński, Andrzej Malinowski, Jacek R. Wilczyński, Paweł Radwan, Michał Radwan, Piotr Kuśnierczyk, Izabela Nowak

Mol Genet Genomics. 2018; 293(3): 601–613. Published online 2017 Dec 12. doi: 10.1007/s00438-017-1404-3

PMCID:: PMC5948266

Abstract Article PDF–978K

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