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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988582.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333684.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92860235.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 75602167.

AP‐3 vesicle uncoating occurs after HOPS‐dependent vacuole tethering

Jannis Schoppe, Muriel Mari, Erdal Yavavli, Kathrin Auffarth, Margarita Cabrera, Stefan Walter, Florian Fröhlich, Christian Ungermann

EMBO J. 2020 Oct 15; 39(20): e105117. Published online 2020 Aug 25. doi: 10.15252/embj.2020105117

PMCID:: PMC7560216

Abstract Article PDF–3.6M

Select item 72597928.

Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs

Jon M. Laurent, Riddhiman K. Garge, Ashley I. Teufel, Claus O. Wilke, Aashiq H. Kachroo, Edward M. Marcotte

PLoS Biol. 2020 May; 18(5): e3000627. Published online 2020 May 18. doi: 10.1371/journal.pbio.3000627

PMCID:: PMC7259792

Abstract Article PDF–2.8M

Select item 70752599.

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

Fujun Zhou, Hongen Zhang, Shardul D. Kulkarni, Jon R. Lorsch, Alan G. Hinnebusch

RNA. 2020 Apr; 26(4): 419–438. doi: 10.1261/rna.073536.119

PMCID:: PMC7075259

Abstract Article PDF–2.1M

Select item 689895610.

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

Shardul D. Kulkarni, Fujun Zhou, Neelam Dabas Sen, Hongen Zhang, Alan G. Hinnebusch, Jon R. Lorsch

BMC Biol. 2019; 17: 101. Published online 2019 Dec 6. doi: 10.1186/s12915-019-0718-5

PMCID:: PMC6898956

Abstract Article PDF–2.9M

Select item 641183711.

A network of eIF2β interactions with eIF1 and Met-tRNA_i promotes accurate start codon selection by the translation preinitiation complex

Anil Thakur, Laura Marler, Alan G Hinnebusch

Nucleic Acids Res. 2019 Mar 18; 47(5): 2574–2593. Published online 2018 Dec 21. doi: 10.1093/nar/gky1274

PMCID:: PMC6411837

Abstract Article PDF–5.9M

Select item 634717012.

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation

Fabio Pereira, Mandy Rettel, Frank Stein, Mikhail M. Savitski, Ian Collinson, Karin Römisch

PLoS One. 2019; 14(1): e0211180. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0211180

PMCID:: PMC6347170

Abstract Article PDF–16M

Select item 611359813.

Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation

Ora Haimov, Urmila Sehrawat, Ana Tamarkin-Ben Harush, Anat Bahat, Anna Uzonyi, Alexander Will, Hiroyuki Hiraishi, Katsura Asano, Rivka Dikstein

Mol Cell Biol. 2018 Sep 15; 38(18): e00139-18. Prepublished online 2018 Jul 9. Published online 2018 Aug 28. doi: 10.1128/MCB.00139-18

PMCID:: PMC6113598

Abstract Article PDF–1.9M

Select item 593910814.

eIF1 Loop 2 interactions with Met-tRNA_i control the accuracy of start codon selection by the scanning preinitiation complex

Anil Thakur, Alan G. Hinnebusch

Proc Natl Acad Sci U S A. 2018 May 1; 115(18): E4159–E4168. Published online 2018 Apr 16. doi: 10.1073/pnas.1800938115

PMCID:: PMC5939108

Abstract Article PDF–1.5M

Select item 575602515.

eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast

Pilar Martin-Marcos, Fujun Zhou, Charm Karunasiri, Fan Zhang, Jinsheng Dong, Jagpreet Nanda, Shardul D Kulkarni, Neelam Dabas Sen, Mercedes Tamame, Michael Zeschnigk, Jon R Lorsch, Alan G Hinnebusch

eLife. 2017; 6: e31250. Published online 2017 Dec 5. doi: 10.7554/eLife.31250

PMCID:: PMC5756025

Abstract Article PDF–2.5M

Select item 520434816.

A novel translational control mechanism involving RNA structures within coding sequences

Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez

Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116

Correction in:: Genome Res. 2017 Apr; 27(4): 663.

PMCID:: PMC5204348

Abstract Article PDF–1.3M

Select item 453485517.

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

Jose L. Llácer, Tanweer Hussain, Laura Marler, Colin Echeverría Aitken, Anil Thakur, Jon R. Lorsch, Alan G. Hinnebusch, V. Ramakrishnan

Mol Cell. 2015 Aug 6; 59(3): 399–412. doi: 10.1016/j.molcel.2015.06.033

PMCID:: PMC4534855

Abstract Article

Select item 451323018.

The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo

Jyothsna Visweswaraiah, Yvette Pittman, Thomas E Dever, Alan G Hinnebusch

eLife. 2015; 4: e07939. Published online 2015 Jul 2. doi: 10.7554/eLife.07939

PMCID:: PMC4513230

Abstract Article PDF–3.5M

Select item 421714019.

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

Tanweer Hussain, Jose L. Llácer, Israel S. Fernández, Antonio Munoz, Pilar Martin-Marcos, Christos G. Savva, Jon R. Lorsch, Alan G. Hinnebusch, V. Ramakrishnan

Cell. 2014 Oct 23; 159(3): 597–607. doi: 10.1016/j.cell.2014.10.001

PMCID:: PMC4217140

Abstract Article PDF–3.8M

Select item 391715320.

The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes

Rafael E. Luna, Haribabu Arthanari, Hiroyuki Hiraishi, Barak Akabayov, Leiming Tang, Christian Cox, Michelle A. Markus, Lunet E. Luna, Yuka Ikeda, Ryosuke Watanabe, Edward Bedoya, Cathy Yu, Shums Alikhan, Gerhard Wagner, Katsura Asano

Biochemistry. Author manuscript; available in PMC 2014 Dec 31.

Published in final edited form as: Biochemistry. 2013 Dec 31; 52(52): 9510–9518. Published online 2013 Dec 19. doi: 10.1021/bi4009775