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Items: 1 to 20 of 41

1.
A2ML1 Inhibits Esophageal Squamous Cell Carcinoma Progression and Serves as a Novel Prognostic Biomarker
Xiaoyun Zhang, Chaogui Tang, Jianchun Lian, Yuzhang Jiang
Can J Gastroenterol Hepatol. 2023; 2023: 5557546. Published online 2023 Nov 3. doi: 10.1155/2023/5557546
PMCID:
PMC10637849
AbstractArticlePDF–1.5M
2.
TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle
Mol Cell. Author manuscript; available in PMC 2024 Mar 16.
Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023
PMCID:
PMC10112281
AbstractArticlePDF–2.4M
3.
Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media
Regie Lyn P. Santos-Cortez, Kimberly Mae C. Ong, Angeli Carlos-Hiceta, Ma. Leah C. Tantoco, Talitha Karisse L. Yarza, Ma. Luz San Agustin, Melquiadesa Pedro, Teresa Luisa G. Cruz, Eva Maria Cutiongco-de la Paz, Generoso T. Abes, Erasmo Gonzalo d.V. Llanes, Abner L. Chan, Charlotte M. Chiong, Maria Rina T. Reyes-Quintos
Genet Test Mol Biomarkers. January 2023; 27(1): 12–17. Published online 2023 Jan 31. doi: 10.1089/gtmb.2022.0171
PMCID:
PMC9902046
AbstractArticlePDF–218K
4.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
A functional reference map of the RNF8 interactome in cancer
Chuanyang Liu, Jingyu Kuang, Yuxuan Wang, Ting Duan, Lu Min, Chenyu Lu, Tianyi Zhang, Ruifen Chen, Ying Wu, Lingyun Zhu
Biol Direct. 2022; 17: 17. Published online 2022 Jul 13. doi: 10.1186/s13062-022-00331-z
PMCID:
PMC9277853
AbstractArticlePDF–5.9M
7.
Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family
Nadia Sukusu Nielsen, Alessandra Zarantonello, Seandean Lykke Harwood, Kathrine Tejlgård Jensen, Katarzyna Kjøge, Ida B. Thøgersen, Leif Schauser, Jesper Lykkegaard Karlsen, Gregers R. Andersen, Jan J. Enghild
Nat Commun. 2022; 13: 3033. Published online 2022 May 31. doi: 10.1038/s41467-022-30758-x
PMCID:
PMC9156758
AbstractArticlePDF–2.9M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
9.
Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim
Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6
PMCID:
PMC8566473
AbstractArticlePDF–2.7M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
The clinical significance of A2ML1 variants in Noonan syndrome has to be reconsidered
Julia Brinkmann, Christina Lissewski, Valentina Pinna, Yoann Vial, Francesca Pantaleoni, Francesca Lepri, Paola Daniele, Birute Burnyte, Goran Cuturilo, Christine Fauth, Alper Gezdirici, Dieter Kotzot, Elif Yılmaz Güleç, Violeta Iotova, Denny Schanze, Francis Ramond, Markéta Havlovicová, Gulen Eda Utine, Pelin Ozlem Simsek-Kiper, Milena Stoyanova, Alain Verloes, Alessandro De Luca, Marco Tartaglia, Hélène Cavé, Martin Zenker
Eur J Hum Genet. 2021 Mar; 29(3): 524–527. Published online 2020 Oct 20. doi: 10.1038/s41431-020-00743-3
PMCID:
PMC7940614
AbstractArticlePDF–616K
12.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
13.
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull
PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606
PMCID:
PMC7392334
AbstractArticlePDF–2.7M
14.
A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection
Amy T. Y. Yeung, Yoon Ha Choi, Amy H. Y. Lee, Christine Hale, Hannes Ponstingl, Derek Pickard, David Goulding, Mark Thomas, Erin Gill, Jong Kyoung Kim, Allan Bradley, Robert E. W. Hancock, Gordon Dougan
mBio. 2019 Sep-Oct; 10(5): e02169-19. Published online 2019 Oct 8. doi: 10.1128/mBio.02169-19
PMCID:
PMC6786873
AbstractArticlePDF–2.2M
15.
A2ML1 and otitis media: novel variants, differential expression and relevant pathways
Eric D. Larson, Jose Pedrito M. Magno, Matthew J. Steritz, Erasmo Gonzalo d.V. Llanes, Jonathan Cardwell, Melquiadesa Pedro, Tori Bootpetch Roberts, Elisabet Einarsdottir, Rose Anne Q. Rosanes, Christopher Greenlee, Rachel Ann P. Santos, Ayesha Yousaf, Sven-Olrik Streubel, Aileen Trinidad R. Santos, Amanda G. Ruiz, Sheryl Mae Lagrana-Villagracia, Dylan Ray, Talitha Karisse L. Yarza, Melissa A. Scholes, Catherine B. Anderson, Anushree Acharya, University of Washington Center for Mendelian Genomics, Samuel P. Gubbels, Michael J. Bamshad, Stephen P. Cass, Nanette R. Lee, Rehan S. Shaikh, Deborah A. Nickerson, Karen L. Mohlke, Jeremy D. Prager, Teresa Luisa G. Cruz, Patricia J. Yoon, Generoso T. Abes, David A. Schwartz, Abner L. Chan, Todd M. Wine, Eva Maria Cutiongco-de la Paz, Norman Friedman, Katerina Kechris, Juha Kere, Suzanne M. Leal, Ivana V. Yang, Janak A. Patel, Ma. Leah C. Tantoco, Saima Riazuddin, Kenny H. Chan, Petri S. Mattila, Maria Rina T. Reyes-Quintos, Zubair M. Ahmed, Herman A. Jenkins, Tasnee Chonmaitree, Lena Hafrén, Charlotte M. Chiong, Regie Lyn P. Santos-Cortez
Hum Mutat. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Hum Mutat. 2019 Aug; 40(8): 1156–1171. Published online 2019 May 21. doi: 10.1002/humu.23769
PMCID:
PMC6711784
AbstractArticlePDF–640K
16.
Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function
Jan B Heidelberger, Andrea Voigt, Marina E Borisova, Giuseppe Petrosino, Stefanie Ruf, Sebastian A Wagner, Petra Beli
EMBO Rep. 2018 Apr; 19(4): e44754. Published online 2018 Feb 21. doi: 10.15252/embr.201744754
PMCID:
PMC5891417
AbstractArticlePDF–1.0M
17.
Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells
Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo
Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31
PMCID:
PMC5839158
AbstractArticlePDF–1.9M
18.
Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies
Gordon K. C. Leung, H. M. Luk, Vincent H. M. Tang, W. W. Gao, Christopher C. Y. Mak, Mullin H. C. Yu, W. L. Wong, Yoyo W. Y. Chu, W. L. Yang, Wilfred H. S. Wong, Alvin C. H. Ma, Anskar Y. H. Leung, D. Y. Jin, Kelvin Y. K. Chan, Judith Allanson, Ivan F. M. Lo, Brian H. Y. Chung
Sci Rep. 2018; 8: 2421. Published online 2018 Feb 5. doi: 10.1038/s41598-018-20894-0
PMCID:
PMC5799236
AbstractArticlePDF–2.9M
19.
Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline
Lei Yu, Robert J. Dawe, Patricia A. Boyle, Chris Gaiteri, Jingyun Yang, Aron S. Buchman, Julie A. Schneider, Konstantinos Arfanakis, Philip L. De Jager, David A. Bennett
JAMA Neurol. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: JAMA Neurol. 2017 Dec 1; 74(12): 1473–1480. doi: 10.1001/jamaneurol.2017.2807
PMCID:
PMC5729739
AbstractArticlePDF–430K
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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