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Select item 112802001.

Novel PLCZ1 mutation caused polyspermy during in vitro fertilization

Ke-Ya Tong, Wei-Wei Liu, Li-Wei Sun, Dong-Yun Liu, Ye-Zhou Xiang, Chong Li, Lu-Wei Chai, Ke Chen, Guo-Ning Huang, Jing-Yu Li

Asian J Androl. 2024 Jul-Aug; 26(4): 389–395. Published online 2024 Mar 5. doi: 10.4103/aja202376

PMCID:: PMC11280200

Abstract Article PDF–3.5M

Select item 108159522.

Phospholipase C Zeta in Human Spermatozoa: A Systematic Review on Current Development and Clinical Application

Alessandra Parrella, Llanos Medrano, Jon Aizpurua, María José Gómez-Torres

Int J Mol Sci. 2024 Jan; 25(2): 1344. Published online 2024 Jan 22. doi: 10.3390/ijms25021344

PMCID:: PMC10815952

Abstract Article PDF–1.1M

Select item 92954783.

Antigen unmasking does not improve the visualization of phospholipase C zeta in human spermatozoa

Xin Meng, Celine Jones, Pedro Melo, Caroline Ross, Ginny Mounce, Tim Child, Kevin Coward

Asian J Androl. 2022 Jul-Aug; 24(4): 345–352. Published online 2021 Dec 3. doi: 10.4103/aja202168

PMCID:: PMC9295478

Abstract Article PDF–4.0M

Select item 83641814.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80084976.

Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice

Jing Dai, Tianlei Zhang, Jing Guo, Qinwei Zhou, Yifan Gu, Jue Zhang, Liang Hu, Yurong Zong, Juan Song, Shuoping Zhang, Can Dai, Fei Gong, Guangxiu Lu, Wei Zheng, Ge Lin

Am J Hum Genet. 2021 Mar 4; 108(3): 469–481. Published online 2021 Feb 23. doi: 10.1016/j.ajhg.2021.02.004

PMCID:: PMC8008497

Abstract Article PDF–2.9M

Select item 75495957.

Novel mutations in the PLCZ1 gene associated with human low or failed fertilization

Ping Yuan, Lingyan Zheng, Hao Liang, Qiyuan Lin, Songbang Ou, Yuqin Zhu, Luhua Lai, Qingxue Zhang, Zuyong He, Wenjun Wang

Mol Genet Genomic Med. 2020 Oct; 8(10): e1470. Published online 2020 Aug 24. doi: 10.1002/mgg3.1470

PMCID:: PMC7549595

Abstract Article PDF–1.3M

Select item 73116218.

Increasing associations between defects in phospholipase C zeta and conditions of male infertility: not just ICSI failure?

Junaid Kashir

J Assist Reprod Genet. 2020 Jun; 37(6): 1273–1293. Published online 2020 Apr 14. doi: 10.1007/s10815-020-01748-z

PMCID:: PMC7311621

Abstract Article PDF–2.7M

Select item 71830329.

A homozygous nonsense mutation of PLCZ1 cause male infertility with oocyte activation deficiency

Fengsong Wang, Jingjing Zhang, Shuai Kong, Chanjuan Li, Zhiguo Zhang, Xiaojin He, Huan Wu, Dongdong Tang, Xiaomin Zha, Qing Tan, Zongliu Duan, Yunxia Cao, Fuxi Zhu

J Assist Reprod Genet. 2020 Apr; 37(4): 821–828. Published online 2020 Mar 7. doi: 10.1007/s10815-020-01719-4

PMCID:: PMC7183032

Abstract Article PDF–1.8M

Select item 616668210.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 607772211.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 598853712.

Oligoasthenoteratozoospermic (OAT) men display altered phospholipase C ζ (PLCζ) localization and a lower percentage of sperm cells expressing PLCζ and post-acrosomal sheath WW domain-binding protein (PAWP)

Nahid Azad, Hamid Nazarian, Marefat Ghaffari Novin, Reza Masteri Farahani, Abbas Piryaei, Mohammad Hassan Heidari, Meghdad Abdollahpour Alitappeh

Bosn J Basic Med Sci. 2018 May; 18(2): 178–184. doi: 10.17305/bjbms.2017.2208

PMCID:: PMC5988537

Abstract Article PDF–945K

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 517190014.

An association between sperm PLCζ levels and varicocele?

Elham Janghorban-Laricheh, Nasim Ghazavi-Khorasgani, Marziyeh Tavalaee, Dina Zohrabi, Homayon Abbasi, Mohammad H. Nasr- Esfahani

J Assist Reprod Genet. 2016 Dec; 33(12): 1649–1655. Published online 2016 Sep 9. doi: 10.1007/s10815-016-0802-5

PMCID:: PMC5171900

Abstract Article PDF–2.4M

Select item 489763115.

Does advancing male age influence the expression levels and localisation patterns of phospholipase C zeta (PLCζ) in human sperm?

Marc Yeste, Celine Jones, Siti Nornadhirah Amdani, Suseela Yelumalai, Ginny Mounce, Sarah J. Martins da Silva, Tim Child, Kevin Coward

Sci Rep. 2016; 6: 27543. Published online 2016 Jun 8. doi: 10.1038/srep27543

PMCID:: PMC4897631

Abstract Article PDF–519K

Select item 475404116.

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

Jessica Escoffier, Hoi Chang Lee, Sandra Yassine, Raoudha Zouari, Guillaume Martinez, Thomas Karaouzène, Charles Coutton, Zine-eddine Kherraf, Lazhar Halouani, Chema Triki, Serge Nef, Nicolas Thierry-Mieg, Sergey N. Savinov, Rafael Fissore, Pierre F. Ray, Christophe Arnoult

Hum Mol Genet. 2016 Mar 1; 25(5): 878–891. Published online 2015 Dec 31. doi: 10.1093/hmg/ddv617

PMCID:: PMC4754041

Abstract Article PDF–1.0M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 459540118.

Phospholipase C-zeta deficiency as a cause for repetitive oocyte fertilization failure during ovarian stimulation for in vitro fertilization with ICSI: a case report

Zahabiya H. Chithiwala, Hoi Chang Lee, David L. Hill, Teru Jellerette-Nolan, Rafael Fissore, Daniel Grow, Daniel A. Dumesic

J Assist Reprod Genet. 2015 Sep; 32(9): 1415–1419. Published online 2015 Jul 15. doi: 10.1007/s10815-015-0531-1

PMCID:: PMC4595401

Abstract Article PDF–551K

Select item 404837719.

Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parameters

Hoi Chang Lee, Margaret Arny, Daniel Grow, Daniel Dumesic, Rafael A. Fissore, Teru Jellerette-Nolan

J Assist Reprod Genet. 2014 Jun; 31(6): 749–756. Published online 2014 Apr 23. doi: 10.1007/s10815-014-0229-9

PMCID:: PMC4048377

Abstract Article PDF–1.2M

Select item 402391020.

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca²⁺ oscillations required for mammalian oocyte activation

Michail Nomikos, Maria Theodoridou, Khalil Elgmati, Dimitris Parthimos, Brian L. Calver, Luke Buntwal, George Nounesis, Karl Swann, F. Anthony Lai

Mol Hum Reprod. 2014 Jun; 20(6): 489–498. Published online 2014 Jan 29. doi: 10.1093/molehr/gau011

PMCID:: PMC4023910

Abstract Article PDF–786K

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