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Select item 105428241.

Functional, biochemical, molecular and clinical characterization of antithrombin c.1157T>C (p.Ile386Thr), a recurrent Polish variant with a founder effect

Anna Weronska, Belen de la Morena-Barrio, Sarah Goldman-Mazur, Maria Eugenia de la Morena-Barrio, José Padilla, Antonia Miñano, Pedro Garrido-Rodriguez, Jacek Trelihski, Daniel Piotr Potaczek, Anita Szczepanek, Anetta Undas, Javier Corral, Ewa Wypasek

Haematologica. 2023 Oct 1; 108(10): 2803–2807. Published online 2023 Apr 6. doi: 10.3324/haematol.2022.282459

PMCID:: PMC10542824

Article PDF–4.0M

Select item 104609562.

Antithrombin Deficiency Is Associated with Prothrombotic Plasma Fibrin Clot Phenotype

Joanna Natorska, Javier Corral, Maria Eugenia de la Morena-Barrio, Carlos Bravo-Pérez, Zsuzsa Bagoly, Zsuzsanna Bereczky, Jacek Treliński, Michał Witkowski, Adrianna Klajmon, Anetta Undas, Michał Ząbczyk

Thromb Haemost. 2023 Sep; 123(9): 880–891. Published online 2023 May 18. doi: 10.1055/s-0043-1768712

PMCID:: PMC10460956

Abstract Article PDF–11M

Select item 102794693.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Sean A. Burnap, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Hashim Ali, Kaloyan Takov, Matthew Fish, Manu Shankar-Hari, Mauro Giacca, Michael H. Malim, Manuel Mayr

Mol Cell Proteomics. 2023 Aug; 22(8): 100600. Published online 2023 Jun 19. doi: 10.1016/j.mcpro.2023.100600

PMCID:: PMC10279469

Abstract Article PDF–3.2M

Select item 101036784.

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M. Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Sci China Life Sci. 2023 Apr 14 : 1–19. doi: 10.1007/s11427-023-2316-2 [Epub ahead of print]

PMCID:: PMC10103678

Abstract Article PDF–2.4M

Select item 98316545.

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice

Wenjie Zhang, Bowen Shi, Shirui Li, Zenglin Liu, Songhan Li, Shuohui Dong, Yugang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong

Front Endocrinol (Lausanne) 2022; 13: 1041027. Published online 2022 Dec 27. doi: 10.3389/fendo.2022.1041027

PMCID:: PMC9831654

Abstract Article PDF–25M

Select item 97531506.

Cullin 2-RBX1 E3 ligase and USP2 regulate antithrombin ubiquitination and stability

Dacai Xu, Jiawen Wu, Jinghong Chen, Liling Jiang, Juan Chen, Wenhao Bao, Xin Chen, Qianqian Yang, Xiaolan Zhang, Leyi Yao, Huabo Su, Jinbao Liu

FASEB J. Author manuscript; available in PMC 2022 Dec 15.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21800. doi: 10.1096/fj.202001146RR

PMCID:: PMC9753150

Abstract Article PDF–1.9M

Select item 95381737.

Native and activated antithrombin inhibits TMPRSS2 activity and SARS‐CoV‐2 infection

Lukas Wettstein, Patrick Immenschuh, Tatjana Weil, Carina Conzelmann, Yasser Almeida‐Hernández, Markus Hoffmann, Amy Kempf, Inga Nehlmeier, Rishikesh Lotke, Moritz Petersen, Steffen Stenger, Frank Kirchhoff, Daniel Sauter, Stefan Pöhlmann, Elsa Sanchez‐Garcia, Jan Münch

J Med Virol. 2022 Sep 16 : 10.1002/jmv.28124. doi: 10.1002/jmv.28124 [Epub ahead of print]

PMCID:: PMC9538173

Abstract Article PDF–2.2M

Select item 92839668.

Two SERPINC1 variants affecting N-glycosylation of Asn224 cause severe thrombophilia not detected by functional assays

Maria Eugenia de la Morena-Barrio, Pierre Suchon, Eva Marie Jacobsen, Nina Iversen, Antonia Miñano, Belén de la Morena-Barrio, Carlos Bravo-Pérez, Jose Padilla, Rosa Cifuentes, Susana Asenjo, Jean François Deleuze, David Alexandre Trégouët, Maria Luisa Lozano, Vicente Vicente, Per Morten Sandset, Pierre Emmanuel Morange, Javier Corral

Blood. 2022 Jul 14; 140(2): 140–151. doi: 10.1182/blood.2021014708

Correction in:: Blood. 2024 Aug 15; 144(7): 795.

PMCID:: PMC9283966

Abstract Article

Select item 90588369.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 881015310.

Downregulation of microRNA-200c-3p alleviates the aggravation of venous thromboembolism by targeting serpin family C member 1

Xiaorong Jian, Dehua Yang, Li Wang, Hongxiang Wang

Bioengineered. 2021; 12(2): 11154–11166. Published online 2021 Nov 29. doi: 10.1080/21655979.2021.2005982

PMCID:: PMC8810153

Abstract Article PDF–2.1M

Select item 877766911.

Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones

Santanu Biswas, Emily Chen, Yamei Gao, Sherwin Lee, Indira Hewlett, Krishnakumar Devadas

Viruses. 2022 Jan; 14(1): 95. Published online 2022 Jan 6. doi: 10.3390/v14010095

PMCID:: PMC8777669

Abstract Article PDF–2.3M

Select item 856647312.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 855250213.

Extracellular histones bind vascular glycosaminoglycans and inhibit the anti-inflammatory function of antithrombin

Indranil Biswas, Sumith R. Panicker, Xiaofeng S. Cai, Hemant Giri, Alireza R. Rezaie

Cell Physiol Biochem. Author manuscript; available in PMC 2022 Oct 16.

Published in final edited form as: Cell Physiol Biochem. 2021 Oct 16; 55(5): 605–617. doi: 10.33594/000000438

PMCID:: PMC8552502

Abstract Article PDF–2.1M

Select item 823444714.

Cis-Segregation of c.1171C>T Stop Codon (p.R391*) in SERPINC1 Gene and c.1691G>A Transition (p.R506Q) in F5 Gene and Selected GWAS Multilocus Approach in Inherited Thrombophilia

Donato Gemmati, Giovanna Longo, Eugenia Franchini, Juliana Araujo Silva, Ines Gallo, Barbara Lunghi, Stefano Moratelli, Iva Maestri, Maria Luisa Serino, Veronica Tisato

Genes (Basel) 2021 Jun; 12(6): 934. Published online 2021 Jun 18. doi: 10.3390/genes12060934

PMCID:: PMC8234447

Abstract Article PDF–925K

Select item 817121315.

Novel Mutation p.Asp374Val of SERPINC1 in a Turkish Family with Inherited Antithrombin Deficiency

Deniz Aslan

Turk J Haematol. 2021 Jun; 38(2): 161–163. Published online 2021 Jun 1. doi: 10.4274/tjh.galenos.2021.2020.0702

PMCID:: PMC8171213

Article PDF–778K

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807872817.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 783236118.

Understanding the andromeda strain – The role of cytokine release, coagulopathy and antithrombin III in SARS-CoV2 critical illness

Nabiel Mir, Alex D'Amico, John Dasher, Ashita Tolwani, Vincent Valentine

Blood Rev. 2021 Jan; 45: 100731. Published online 2020 Jul 3. doi: 10.1016/j.blre.2020.100731

PMCID:: PMC7832361

Abstract Article PDF–1.2M

Select item 782559119.

N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function

Sonia Águila, Rosina Noto, Ginés Luengo-Gil, Salvador Espín, Nataliya Bohdan, María Eugenia de la Morena-Barrio, Julia Peñas, Maria Carmen Rodenas, Vicente Vicente, Javier Corral, Mauro Manno, Irene Martínez-Martínez

Int J Mol Sci. 2021 Jan; 22(2): 516. Published online 2021 Jan 6. doi: 10.3390/ijms22020516

PMCID:: PMC7825591

Abstract Article PDF–1.9M

Select item 752655120.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

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