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Items: 11

Select item 76055211.

Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions

Lori A. Birder, Amanda Wolf-Johnston, Alan J. Wein, Fangzhou Cheng, Mara Grove-Sullivan, Anthony J. Kanai, Alan M. Watson, Donna Stoltz, Simon C. Watkins, Anne M. Robertson, Diane Newman, Roger R. Dmochowski, Edwin K. Jackson

JCI Insight. 2020 Oct 15; 5(20): e140109. Published online 2020 Oct 15. doi: 10.1172/jci.insight.140109

PMCID:: PMC7605521

Abstract Article PDF–1.4M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 42633713.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819

PMCID:: PMC4263371

Abstract Article PDF–7.6M

Select item 37735054.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 31780595.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 28419166.

Four generations of transition-state analogues for human purine nucleoside phosphorylase

Meng-Chiao Ho, Wuxian Shi, Agnes Rinaldo-Matthis, Peter C. Tyler, Gary B. Evans, Keith Clinch, Steven C. Almo, Vern L. Schramm

Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11): 4805–4812. Published online 2010 Mar 8. doi: 10.1073/pnas.0913439107

PMCID:: PMC2841916

Abstract Article PDF–1.7M

Select item 26370507.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 26105128.

Nicotinamide Riboside and Nicotinic Acid Riboside Salvage in Fungi and Mammals: QUANTITATIVE BASIS FOR Urh1 AND PURINE NUCLEOSIDE PHOSPHORYLASE FUNCTION IN NAD⁺METABOLISM

Peter Belenky, Kathryn C. Christensen, Francesca Gazzaniga, Alexandre A. Pletnev, Charles Brenner

J Biol Chem. 2009 Jan 2; 284(1): 158–164. doi: 10.1074/jbc.M807976200

Correction in:: J Biol Chem. 2009 Mar 20; 284(12): 8208.

PMCID:: PMC2610512

Abstract Article PDF–409K

Select item 15603479.

TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice

Ana Toro, Eyal Grunebaum

J Clin Invest. 2006 Oct 2; 116(10): 2717–2726. Published online 2006 Sep 7. doi: 10.1172/JCI25052

PMCID:: PMC1560347

Abstract Article PDF–832K

Select item 155413410.

Deficiency of purine nucleoside phosphorylase activity in thymocytes from the immunodeficient diabetic BB rat.

G Wu, E B Marliss

Clin Exp Immunol. 1991 Nov; 86(2): 260–265. doi: 10.1111/j.1365-2249.1991.tb05807.x

PMCID:: PMC1554134

Summary Page Browse PDF–920K

Select item 37530711.

Role of Purine Nucleoside Phosphorylase in Interactions between 2′,3′-Dideoxyinosine and Allopurinol, Ganciclovir, or Tenofovir

Adrian S. Ray, Loren Olson, Arnold Fridland

Antimicrob Agents Chemother. 2004 Apr; 48(4): 1089–1095. doi: 10.1128/AAC.48.4.1089-1095.2004

PMCID:: PMC375307

Abstract Article PDF–130K

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