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Select item 113616421.

FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton

Asra Almubarak, Qiuwan Zhang, Cheng-Hai Zhang, Noor Abdelwahab, Tsutomu Kume, Andrew B. Lassar, Fred B. Berry

Development. 2024 Aug 15; 151(16): dev202798. Published online 2024 Aug 22. doi: 10.1242/dev.202798

PMCID:: PMC11361642

Abstract Article

Select item 112971412.

FGFR3 drives Aβ-induced tau uptake

Dong Kyu Kim, Kyujin Suh, Junho Park, Sang-Eun Lee, Jihui Han, Sunghoe Chang, Youngsoo Kim, Inhee Mook-Jung

Exp Mol Med. 2024 Jul; 56(7): 1631–1642. Published online 2024 Jul 1. doi: 10.1038/s12276-024-01274-3

PMCID:: PMC11297141

Abstract Article PDF–4.1M

Select item 110146573.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109901564.

ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period

Mengge Sun, Yanjing Gao, Zhenmeiyu Li, Lin Yang, Guoping Liu, Zhejun Xu, Rongliang Guo, Yan You, Zhengang Yang

Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13): e2314802121. Published online 2024 Mar 18. doi: 10.1073/pnas.2314802121

PMCID:: PMC10990156

Abstract Article PDF–13M

Select item 104036405.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 103712526.

Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice

Léa Loisay, Davide Komla-Ebri, Anne Morice, Yann Heuzé, Camille Viaut, Amélie de La Seiglière, Nabil Kaci, Danny Chan, Audrey Lamouroux, Geneviève Baujat, J.H. Duncan Bassett, Graham R. Williams, Laurence Legeai-Mallet

JCI Insight. 2023 Jun 22; 8(12): e168796. Published online 2023 Jun 22. doi: 10.1172/jci.insight.168796

PMCID:: PMC10371252

Abstract Article PDF–16M

Select item 102682407.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 102566858.

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate

Mahdia Taieb, Dima Ghannoum, Lydia Barré, Mohamed Ouzzine

Cell Death Dis. 2023 Jun; 14(6): 355. Published online 2023 Jun 9. doi: 10.1038/s41419-023-05875-0

PMCID:: PMC10256685

Abstract Article PDF–8.3M

Select item 101214689.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 989855210.

Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis

Runze Jin, Hanshu Zhang, Chujiao Lin, Jinqiang Guo, Weiguo Zou, Zhi Chen, Huan Liu

Exp Mol Med. 2023 Jan; 55(1): 69–80. Published online 2023 Jan 4. doi: 10.1038/s12276-022-00914-w

PMCID:: PMC9898552

Abstract Article PDF–9.9M

Select item 977136511.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405

PMCID:: PMC9771365

Abstract Article PDF–17M

Select item 890649412.

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

Maxence Cornille, Stéphanie Moriceau, Roman H. Khonsari, Yann Heuzé, Léa Loisay, Valérie Boitez, Anne Morice, Eric Arnaud, Corinne Collet, Morad Bensidhoum, Nabil Kaci, Nathalie Boddaert, Giovanna Paternoster, Theresa Rauschendorfer, Sabine Werner, Suzanne L. Mansour, Federico Di Rocco, Franck Oury, Laurence Legeai-Mallet

J Exp Med. 2022 Apr 4; 219(4): e20201879. Published online 2022 Mar 7. doi: 10.1084/jem.20201879

PMCID:: PMC8906494

Abstract Article PDF–4.6M

Select item 888790313.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 849232614.

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization

Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma

JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254

PMCID:: PMC8492326

Abstract Article PDF–3.4M

Select item 838311915.

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification

Asra Almubarak, Rotem Lavy, Nikola Srnic, Yawen Hu, Devi Priyanka Maripuri, Tsutomo Kume, Fred B. Berry

J Biol Chem. 2021 Sep; 297(3): 101020. Published online 2021 Jul 29. doi: 10.1016/j.jbc.2021.101020

PMCID:: PMC8383119

Abstract Article PDF–7.9M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 828984717.

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie

Nat Commun. 2021; 12: 4391. Published online 2021 Jul 19. doi: 10.1038/s41467-021-24643-2