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Select item 109359541.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 108987402.

Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing

Daniel C. Sutton, Jonathan C. Andrews, Dylan M. Dolezal, Ye Jin Park, Hongjie Li, Daniel F. Eberl, Shinya Yamamoto, Andrew K. Groves

PLoS One. 2024; 19(2): e0297846. Published online 2024 Feb 27. doi: 10.1371/journal.pone.0297846

PMCID:: PMC10898740

Abstract Article PDF–2.8M

Select item 104505803.

Milton assembles large mitochondrial clusters, mitoballs, to sustain spermatogenesis

Andy Y. Z. Li, Ying Di, Sumaera Rathore, Ason C.-Y. Chiang, Jan Jezek, Hansong Ma

Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2306073120. Published online 2023 Aug 14. doi: 10.1073/pnas.2306073120

PMCID:: PMC10450580

Abstract Article PDF–8.2M

Select item 103988944.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 99815356.

A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes

Karen Jule Nieken, Kathryn O’Brien, Alexander McDonnell, Liudmila Zhaunova, Hiroyuki Ohkura

Chromosoma. 2023; 132(1): 1–18. Published online 2023 Jan 17. doi: 10.1007/s00412-023-00784-9

PMCID:: PMC9981535

Abstract Article PDF–3.4M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 84962778.

A cross-species approach for the identification of Drosophila male sterility genes

Kimihide Ibaraki, Mihoko Nakatsuka, Takashi Ohsako, Masahide Watanabe, Yu Miyazaki, Machi Shirakami, Timothy L Karr, Rikako Sanuki, Masatoshi Tomaru, Toshiyuki Takano-Shimizu-Kouno

G3 (Bethesda) 2021 Aug; 11(8): jkab183. Published online 2021 May 29. doi: 10.1093/g3journal/jkab183

PMCID:: PMC8496277

Abstract Article PDF–421K

Select item 79300539.

Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging

Liam C. Hunt, Bronwen Schadeberg, Jared Stover, Benard Haugen, Vishwajeeth Pagala, Yong-Dong Wang, Jason Puglise, Elisabeth R. Barton, Junmin Peng, Fabio Demontis

Nat Commun. 2021; 12: 1418. Published online 2021 Mar 3. doi: 10.1038/s41467-021-21738-8

PMCID:: PMC7930053

Abstract Article PDF–9.9M

Select item 790962910.

Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

Andrey A. Parkhitko, Arashdeep Singh, Sharon Hsieh, Yanhui Hu, Richard Binari, Christopher J. Lord, Sridhar Hannenhalli, Colm J. Ryan, Norbert Perrimon

PLoS Genet. 2021 Feb; 17(2): e1009354. Published online 2021 Feb 16. doi: 10.1371/journal.pgen.1009354

PMCID:: PMC7909629

Abstract Article PDF–4.6M

Select item 757883011.

Proteomic analysis of Drosophila CLOCK complexes identifies rhythmic interactions with SAGA and Tip60 complex component NIPPED-A

Guruswamy Mahesh, Gustavo B. S. Rivas, Courtney Caster, Evan B. Ost, Ravi Amunugama, Richard Jones, David L. Allen, Paul E. Hardin

Sci Rep. 2020; 10: 17951. Published online 2020 Oct 21. doi: 10.1038/s41598-020-75009-5

PMCID:: PMC7578830

Abstract Article PDF–2.5M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 669717113.

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Liam C. Hunt, Jared Stover, Benard Haugen, Timothy I. Shaw, Yuxin Li, Vishwajeeth R. Pagala, David Finkelstein, Elisabeth R. Barton, Yiping Fan, Myriam Labelle, Junmin Peng, Fabio Demontis

Cell Rep. Author manuscript; available in PMC 2019 Aug 15.

Published in final edited form as: Cell Rep. 2019 Jul 30; 28(5): 1268–1281.e6. doi: 10.1016/j.celrep.2019.06.094

PMCID:: PMC6697171

Abstract Article PDF–1.7M

Select item 664389114.

An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila

Lutz Kockel, Catherine Griffin, Yaseen Ahmed, Lauren Fidelak, Arjun Rajan, Ethan P. Gould, Myles Haigney, Benjamin Ralston, Rex J. Tercek, Lara Galligani, Sagar Rao, Lutfi Huq, Hersh K. Bhargava, Ailis C. Dooner, Emily G. Lemmerman, Ruby F. Malusa, Tran H. Nguyen, Julie S. Chung, Sara M. Gregory, Kiyomasa M. Kuwana, Jonathan T. Regenold, Alexander Wei, Jake Ashton, Patrick Dickinson, Kate Martel, Connie Cai, Carissa Chen, Stephen Price, Jeffrey Qiao, David Shepley, Joanna Zhang, Meghana Chalasani, Khanh Nguyen, August Aalto, ByungJun Kim, Erik Tazawa-Goodchild, Amanda Sherwood, Ahmad Rahman, Sum Ying Celeste Wu, Joel Lotzkar, Serena Michaels, Hillary Aristotle, Antigone Clark, Grace Gasper, Evan Xiang, Frieda Luna Schlör, Melissa Lu, Kate Haering, Julia Friberg, Alyssa Kuwana, Jonathan Lee, Alan Liu, Emma Norton, Leena Hamad, Clara Lee, Dara Okeremi, Harry diTullio, Kat Dumoulin, Sun Yu Gordon Chi, Grayson S. Derossi, Rose E. Horowitch, Elias C. Issa, Dan T. Le, Bryce C. Morales, Ayush Noori, Justin Shao, Sophia Cho, Mai N. Hoang, Ian M. Johnson, Katherine C. Lee, Maria Lee, Elizabeth A. Madamidola, Katrina E. Schmitt, Gabriel Byan, Taeyoung Park, Jonathan Chen, Alexi Monovoukas, Madison J. Kang, Tanner McGowan, Joseph J. Walewski, Brennan Simon, Sophia J. Zu, Gregory P. Miller, Kate B. Fitzpatrick, Nicole Lantz, Elizabeth Fox, Jeanette Collette, Richard Kurtz, Chris Duncan, Ryan Palmer, Cheryl Rotondo, Eric Janicki, Townley Chisholm, Anne Rankin, Sangbin Park, Seung K. Kim

G3 (Bethesda) 2019 Jul; 9(7): 2097–2106. Published online 2019 Apr 30. doi: 10.1534/g3.119.400105

PMCID:: PMC6643891

Abstract Article PDF–1.4M

Select item 657749415.

bendless, a Drosophila gene affecting neuronal connectivity, encodes a ubiquitin-conjugating enzyme homolog

CE Oh, R McMahon, S Benzer, MA Tanouye

J Neurosci. 1994 May 1; 14(5): 3166–3179. doi: 10.1523/JNEUROSCI.14-05-03166.1994

PMCID:: PMC6577494

Abstract PDF–2.9M

Select item 642956416.

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

Kent Nybakken, Steven A Vokes, Ting-Yi Lin, Andrew P McMahon, Norbert Perrimon

Nat Genet. Author manuscript; available in PMC 2019 Mar 22.

Published in final edited form as: Nat Genet. 2005 Dec; 37(12): 1323–1332. Published online 2005 Nov 20. doi: 10.1038/ng1682

PMCID:: PMC6429564

Abstract Article PDF–1.8M

Select item 573905617.

Validating Candidate Congenital Heart Disease Genes in Drosophila

Jun-Yi Zhu, Yulong Fu, Adam Richman, Zhe Han

Bio Protoc. 2017 Jun 20; 7(12): e2350. Published online 2017 Jun 20. doi: 10.21769/BioProtoc.2350

PMCID:: PMC5739056

Abstract Article PDF–2.8M

Select item 571445618.

Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster

Ravi Das, Shatabdi Bhattacharjee, Atit A. Patel, Jenna M. Harris, Surajit Bhattacharya, Jamin M. Letcher, Sarah G. Clark, Sumit Nanda, Eswar Prasad R. Iyer, Giorgio A. Ascoli, Daniel N. Cox

Genetics. 2017 Dec; 207(4): 1401–1421. Published online 2017 Oct 12. doi: 10.1534/genetics.117.300393

PMCID:: PMC5714456

Abstract Article PDF–4.4M

Select item 570780519.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900220.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

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