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Transcriptomic Insights into Host Metabolism and Immunity Changes after Parasitization by Leptopilina myrica

Junwei Zhang, Jieyu Shan, Wenqi Shi, Ting Feng, Yifeng Sheng, Zixuan Xu, Zhi Dong, Jianhua Huang, Jiani Chen

Insects. 2024 May; 15(5): 352. Published online 2024 May 14. doi: 10.3390/insects15050352

PMCID:: PMC11122121

Abstract Article PDF–2.4M

Select item 109455082.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109454003.

When the microbiome shapes the host: immune evolution implications for infectious disease

Mark A. Hanson

Philos Trans R Soc Lond B Biol Sci. May 6, 2024; 379(1901): 20230061. Published online March 18, 2024. doi: 10.1098/rstb.2023.0061

PMCID:: PMC10945400

Abstract Article PDF–667K

Select item 109359544.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 108693625.

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy

Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton

Commun Biol. 2024; 7: 183. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05834-1

PMCID:: PMC10869362

Abstract Article PDF–6.1M

Select item 107871066.

Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype

Yaosi Liang, Christopher Pan, Tao Yin, Lu Wang, Xia Gao, Ergang Wang, Holly Quang, De Huang, Lianmei Tan, Kun Xiang, Yu Wang, Peter B. Alexander, Qi‐Jing Li, Tso‐Pang Yao, Zhao Zhang, Xiao‐Fan Wang

Adv Sci (Weinh) 2024 Jan; 11(2): 2303489. Published online 2023 Nov 15. doi: 10.1002/advs.202303489

PMCID:: PMC10787106

Abstract Article PDF–5.0M

Select item 107773517.

Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster

Gabriela Krejčová, Ivan Saloň, Vojtěch Klimša, Pavel Ulbrich, Ayse Beyza Aysan, Adam Bajgar, František Štěpánek

ACS Biomater Sci Eng. 2024 Jan 8; 10(1): 355–364. Published online 2023 Dec 4. doi: 10.1021/acsbiomaterials.3c01199

PMCID:: PMC10777351

Abstract Article PDF–7.3M

Select item 107575638.

Inhibition of translation termination by the antimicrobial peptide Drosocin

Kyle Mangano, Dorota Klepacki, Irueosa Ohanmu, Chetana Baliga, Weiping Huang, Alexandra Brakel, Andor Krizsan, Yury S. Polikanov, Ralf Hoffmann, Nora Vázquez-Laslop, Alexander S. Mankin

Nat Chem Biol. Author manuscript; available in PMC 2023 Dec 30.

Published in final edited form as: Nat Chem Biol. 2023 Sep; 19(9): 1082–1090. Published online 2023 Mar 30. doi: 10.1038/s41589-023-01300-x

PMCID:: PMC10757563

Abstract Article PDF–3.0M

Select item 106974169.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 1058097210.

Delayed host mortality and immune response upon infection with P. aeruginosa persister cells

Cody J. Hastings, Maya V. Keledjian, Laura Palanker Musselman, Cláudia N. H. Marques

Infect Immun. 2023 Oct; 91(10): e00246-23. Published online 2023 Sep 21. doi: 10.1128/iai.00246-23

PMCID:: PMC10580972

Abstract Article PDF–967K

Select item 1054721111.

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Kriti Gupta, Sveta Chakrabarti, Vishnu Janardan, Nishita Gogia, Sanghita Banerjee, Swarna Srinivas, Deepthi Mahishi, Sandhya S. Visweswariah

PLoS Genet. 2023 Sep; 19(9): e1010962. Published online 2023 Sep 21. doi: 10.1371/journal.pgen.1010962

PMCID:: PMC10547211

Abstract Article PDF–2.9M

Select item 1045186712.

Peroxiredoxins Play an Important Role in the Regulation of Immunity and Aging in Drosophila

Olena Odnokoz, Noah Earland, Marziyeh Badinloo, Vladimir I. Klichko, Judith Benes, William C. Orr, Svetlana N. Radyuk

Antioxidants (Basel) 2023 Aug; 12(8): 1616. Published online 2023 Aug 15. doi: 10.3390/antiox12081616

PMCID:: PMC10451867

Abstract Article PDF–4.1M

Select item 1044963213.

Structural basis for translation inhibition by the glycosylated drosocin peptide

Timm O. Koller, Martino Morici, Max Berger, Haaris A. Safdari, Deepti S. Lele, Bertrand Beckert, Kanwal J. Kaur, Daniel N. Wilson

Nat Chem Biol. 2023; 19(9): 1072–1081. Published online 2023 Mar 30. doi: 10.1038/s41589-023-01293-7

PMCID:: PMC10449632

Abstract Article PDF–11M

Select item 1043400414.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 1026415715.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 1016332416.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 1006635217.

Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann

J Innate Immun. 2023 Jan-Dec; 15(1): 442–467. Published online 2023 Mar 30. doi: 10.1159/000529096

PMCID:: PMC10066352

Abstract Article PDF–6.1M

Select item 1005234918.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628