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Select item 111455511.

Adipose tissue macrophage–derived microRNA-210-3p disrupts systemic insulin sensitivity by silencing GLUT4 in obesity

Debarun Patra, Palla Ramprasad, Shivam Sharma, Upalabdha Dey, Vinod Kumar, Satpal Singh, Suman Dasgupta, Aditya Kumar, Kulbhushan Tikoo, Durba Pal

J Biol Chem. 2024 Jun; 300(6): 107328. Published online 2024 Apr 26. doi: 10.1016/j.jbc.2024.107328

PMCID:: PMC11145551

Abstract Article PDF–3.2M

Select item 110940732.

Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance

Jessie E Buth, Catherine E Dyevich, Alexandra Rubin, Chengbing Wang, Lei Gao, Tessa Marks, Michael RM Harrison, Jennifer H Kong, M Elizabeth Ross, Bennett G Novitch, Caroline Alayne Pearson

EMBO Rep. 2024 May; 25(5): 2202–2219. Published online 2024 Apr 10. doi: 10.1038/s44319-024-00131-8

PMCID:: PMC11094073

Abstract Article PDF–13M

Select item 110722573.

Effects of short-term endurance and strength exercise in the molecular regulation of skeletal muscle in hyperinsulinemic and hyperglycemic Slc2a4^+/− mice

Vitor Rosetto Muñoz, José Diego Botezelli, Rafael Calais Gaspar, Alisson L. da Rocha, Renan Fudoli Lins Vieira, Barbara Moreira Crisol, Renata Rosseto Braga, Matheus Brandemarte Severino, Susana Castelo Branco Ramos Nakandakari, Gabriel Calheiros Antunes, Sérgio Q. Brunetto, Celso D. Ramos, Lício Augusto Velloso, Fernando Moreira Simabuco, Leandro Pereira de Moura, Adelino Sanchez Ramos da Silva, Eduardo Rochete Ropelle, Dennys Esper Cintra, José Rodrigo Pauli

Cell Mol Life Sci. 2023 May; 80(5): 122. Published online 2023 Apr 13. doi: 10.1007/s00018-023-04771-2

PMCID:: PMC11072257

Abstract Article PDF–7.5M

Select item 110146574.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 107553635.

Glucose restriction enhances oxidative fiber formation: A multi-omic signal network involving AMPK and CaMK2

Kaiyi Zhang, Ning Xie, Huaqiong Ye, Jiakun Miao, Boce Xia, Yu Yang, Huanqi Peng, Shuang Xu, Tianwen Wu, Cong Tao, Jinxue Ruan, Yanfang Wang, Shulin Yang

iScience. 2024 Jan 19; 27(1): 108590. Published online 2023 Nov 29. doi: 10.1016/j.isci.2023.108590

PMCID:: PMC10755363

Abstract Article PDF–7.2M

Select item 107415616.

Phosphorylation of Syntaxin 4 by the Insulin Receptor Drives Exocytic SNARE Complex Formation to Deliver GLUT4 to the Cell Surface

Dimitrios Kioumourtzoglou, Hannah L. Black, Mohammed Al Tobi, Rachel Livingstone, John R. Petrie, James G. Boyle, Gwyn W. Gould, Nia J. Bryant

Biomolecules. 2023 Dec; 13(12): 1738. Published online 2023 Dec 2. doi: 10.3390/biom13121738

PMCID:: PMC10741561

Abstract Article PDF–4.3M

Select item 106991047.

LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes

Fumitaka Kawakami, Motoki Imai, Yuki Isaka, Mark R. Cookson, Hiroko Maruyama, Makoto Kubo, Matthew J. Farrer, Makoto Kanzaki, Rei Kawashima, Tatsunori Maekawa, Shun Tamaki, Yoshifumi Kurosaki, Fumiaki Kojima, Kenichi Ohba, Takafumi Ichikawa

FEBS Open Bio. 2023 Dec; 13(12): 2200–2214. Published online 2023 Oct 26. doi: 10.1002/2211-5463.13717

PMCID:: PMC10699104

Abstract Article PDF–8.2M

Select item 102403468.

Bone marrow mesenchymal stem cell‐derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway

Hongwei Shi, Xiaojing Hao, Yaqin Sun, Huilin Zhang, Yating Zhao, Bin Wang, Jiayin Lu, Wei Hou, Yi Yan, Xiuju Yu, Linli Xue, Xiaomao Luo, Haidong Wang

FEBS Open Bio. 2023 Jun; 13(6): 1015–1026. Published online 2023 May 2. doi: 10.1002/2211-5463.13615

PMCID:: PMC10240346

Abstract Article PDF–1.5M

Select item 101718679.

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Jonas R Knudsen, Kaspar W Persson, Carlos Henriquez-Olguin, Zhencheng Li, Nicolas Di Leo, Sofie A Hesselager, Steffen H Raun, Janne R Hingst, Raphaël Trouillon, Martin Wohlwend, Jørgen FP Wojtaszewski, Martin AM Gijs, Thomas Elbenhardt Jensen

eLife. 2023; 12: e83338. Published online 2023 Apr 19. doi: 10.7554/eLife.83338

PMCID:: PMC10171867

Abstract Article PDF–7.8M

Select item 1008674110.

Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo

Xinlei Yao, Lei Liu, Wenjun Shao, Miao Bai, Xiaohan Ding, Geng Wang, Shuyue Wang, Lihua Zheng, Ying Sun, Guannan Wang, Yanxin Huang, Chunlei Yu, Zhenbo Song, Yongli Bao, Shaonian Yang, Luguo Sun

Int J Biol Sci. 2023; 19(5): 1579–1596. Published online 2023 Mar 5. doi: 10.7150/ijbs.80125

PMCID:: PMC10086741

Abstract Article PDF–6.8M

Select item 971277611.

GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells

Jessica Laiman, Yen-Jung Hsu, Julie Loh, Wei-Chun Tang, Mei-Chun Chuang, Hui-Kang Liu, Wei-Shun Yang, Bi-Chang Chen, Lee-Ming Chuang, Yi-Cheng Chang, Ya-Wen Liu

J Cell Biol. 2023 Feb 6; 222(2): e202102119. Published online 2022 Nov 29. doi: 10.1083/jcb.202102119

PMCID:: PMC9712776

Abstract Article PDF–6.9M

Select item 971055912.

A Novel Mutation in Slc2a4 as a Mouse Model of Fatigue

Marleen H. M. de Groot, Carlos M. Castorena, Kimberly H. Cox, Vivek Kumar, Jennifer A. Mohawk, Newaz I. Ahmed, Joseph S. Takahashi

Genes Brain Behav. Author manuscript; available in PMC 2022 Nov 30.

Published in final edited form as: Genes Brain Behav. 2019 Nov; 18(8): e12578. Published online 2019 May 23. doi: 10.1111/gbb.12578

PMCID:: PMC9710559

Abstract Article PDF–1.5M

Select item 938646413.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 932773714.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 920741315.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

Select item 887544116.

MYH10 Governs Adipocyte Function and Adipogenesis through Its Interaction with GLUT4

Nadav Kislev, Lisa Mor-Yossef Moldovan, Rakefet Barak, Michael Egozi, Dafna Benayahu

Int J Mol Sci. 2022 Feb; 23(4): 2367. Published online 2022 Feb 21. doi: 10.3390/ijms23042367

PMCID:: PMC8875441

Abstract Article PDF–4.8M

Select item 876727717.

Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion

Hannah L. Black, Rachel Livingstone, Cynthia C. Mastick, Mohammed Al Tobi, Holly Taylor, Angéline Geiser, Laura Stirrat, Dimitrios Kioumourtzoglou, John R. Petrie, James G. Boyle, Nia J. Bryant, Gwyn W. Gould

J Cell Sci. 2022 Jan 1; 135(1): jcs258375. Published online 2022 Jan 10. doi: 10.1242/jcs.258375

PMCID:: PMC8767277

Abstract Article

Select item 868920918.

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues

Austin M. Reilly, Shijun Yan, Menghao Huang, Surabhi D. Abhyankar, Jason M. Conley, Robert N. Bone, Natalie D. Stull, Daniel J. Horan, Hyun C. Roh, Alexander G. Robling, Aaron C. Ericsson, Xiaocheng C. Dong, Carmella Evans-Molina, Hongxia Ren

J Biol Chem. 2022 Jan; 298(1): 101431. Published online 2021 Nov 18. doi: 10.1016/j.jbc.2021.101431

PMCID:: PMC8689209

Abstract Article PDF–3.3M

Select item 837925619.

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

Shinji Furuzono, Tetsuya Kubota, Junki Taura, Masahiro Konishi, Asuka Naito, Masato Tsutsui, Hiroshi Karasawa, Naoto Kubota, Takashi Kadowaki

Commun Biol. 2021; 4: 994. Published online 2021 Aug 20. doi: 10.1038/s42003-021-02491-6

PMCID:: PMC8379256

Abstract Article PDF–1.4M

Select item 836388620.

Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice

Belén Picatoste, Lucie Yammine, Rosemary A. Leahey, David Soares, Emma F. Johnson, Paul Cohen, Timothy E. McGraw

Mol Metab. 2021 Nov; 53: 101305. Published online 2021 Jul 21. doi: 10.1016/j.molmet.2021.101305

PMCID:: PMC8363886

Abstract Article PDF–3.8M

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