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Items: 1 to 20 of 100

1.
Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis
Aaron L Moye, Antonella FM Dost, Robert Ietswaart, Shreoshi Sengupta, VanNashlee Ya, Chrystal Aluya, Caroline G Fahey, Sharon M Louie, Margherita Paschini, Carla F Kim
EMBO J. 2024 Jul; 43(14): 2843–2861. Published online 2024 May 16. doi: 10.1038/s44318-024-00113-5
PMCID:
PMC11251082
AbstractArticlePDF–4.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Iron/ROS/Itga3 mediated accelerated depletion of hippocampal neural stem cell pool contributes to cognitive impairment after hemorrhagic stroke
Xuyang Zhang, Huanhuan Li, Haomiao Wang, Qian Zhang, Xueyun Deng, Shuixian Zhang, Long Wang, Chao Guo, Fengchun Zhao, Yi Yin, Tengyuan Zhou, Jun Zhong, Hui Feng, Wei Chen, Jun Zhang, Hua Feng, Rong Hu
Redox Biol. 2024 May; 71: 103086. Published online 2024 Feb 13. doi: 10.1016/j.redox.2024.103086
PMCID:
PMC10883838
AbstractArticlePDF–13M
4.
Integrin α3 promotes Th17 cell polarization and extravasation during autoimmune neuroinflammation.
Eunchong Park, William E. Barclay, Alejandro Barrera, Tzu-Chieh Liao, Harmony R. Salzler, Timothy E. Reddy, Mari L. Shinohara, Maria Ciofani
Sci Immunol. Author manuscript; available in PMC 2024 Jan 27.
Published in final edited form as: Sci Immunol. 2023 Oct 20; 8(88): eadg7597. Published online 2023 Oct 13. doi: 10.1126/sciimmunol.adg7597
PMCID:
PMC10821720
AbstractArticlePDF–3.2M
5.
The Role of α3β1 Integrin Modulation on Fabry Disease Podocyte Injury and Kidney Impairment
Bruna Bosquetti, Aline Aparecida Santana, Paulo Cézar Gregório, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Julia Budag, Célia Regina Cavichiolo Franco, Edneia Amancio de Souza Ramos, Fellype Carvalho Barreto, Andréa Emilia Marques Stinghen
Toxins (Basel) 2023 Dec; 15(12): 700. Published online 2023 Dec 14. doi: 10.3390/toxins15120700
PMCID:
PMC10748128
AbstractArticlePDF–12M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Integrin α3β1 on tumor keratinocytes is essential to maintain tumor growth and promotes a tumor-supportive keratinocyte secretome.
Whitney M. Longmate, Scott Varney, Derek Power, Rakshitha Pandulal Miskin, Karl E. Anderson, Lori DeFreest, Livingston Van De Water, C. Michael DiPersio
J Invest Dermatol. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: J Invest Dermatol. 2021 Jan; 141(1): 142–151.e6. Published online 2020 May 23. doi: 10.1016/j.jid.2020.05.080
PMCID:
PMC7680721
AbstractArticlePDF–2.2M
8.
Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis
Veronika Ramovs, Ana Krotenberg Garcia, Ji-Ying Song, Iris de Rink, Maaike Kreft, Roel Goldschmeding, Arnoud Sonnenberg
Life Sci Alliance. 2020 Jul; 3(7): e202000645. Published online 2020 May 18. doi: 10.26508/lsa.202000645
PMCID:
PMC7240742
AbstractArticlePDF–3.9M
9.
Keratinocyte integrin α3β1 promotes secretion of IL-1α to effect paracrine regulation of fibroblast gene expression and differentiation
Rui Zheng, Whitney M. Longmate, Lori DeFreest, Scott Varney, Lei Wu, C. Michael DiPersio, Livingston Van De Water
J Invest Dermatol. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: J Invest Dermatol. 2019 Sep; 139(9): 2029–2038.e3. Published online 2019 Mar 13. doi: 10.1016/j.jid.2019.02.025
PMCID:
PMC7171922
AbstractArticlePDF–1.9M
10.
Expression of Laminin Receptors in Schwann Cell Differentiation: Evidence for Distinct Roles
Stefano C. Previtali, Alessandro Nodari, Carla Taveggia, Celia Pardini, Giorgia Dina, Antonello Villa, Lawrence Wrabetz, Angelo Quattrini, M. Laura Feltri
J Neurosci. 2003 Jul 2; 23(13): 5520–5530. doi: 10.1523/JNEUROSCI.23-13-05520.2003
PMCID:
PMC6741230
AbstractArticlePDF–1.3M
11.
Integrin Requirement for Hippocampal Synaptic Plasticity and Spatial Memory
Chi-Shing Chan, Edwin J. Weeber, Sindhu Kurup, J. David Sweatt, Ronald L. Davis
J Neurosci. 2003 Aug 6; 23(18): 7107–7116. doi: 10.1523/JNEUROSCI.23-18-07107.2003
PMCID:
PMC6740650
AbstractArticlePDF–858K
12.
β1 Integrins in Radial Glia But Not in Migrating Neurons Are Essential for the Formation of Cell Layers in the Cerebral Cortex
Richard Belvindrah, Diana Graus-Porta, Sandra Goebbels, Klaus-Armin Nave, Ulrich Müller
J Neurosci. 2007 Dec 12; 27(50): 13854–13865. doi: 10.1523/JNEUROSCI.4494-07.2007
PMCID:
PMC6673609
AbstractArticlePDF–972K
13.
Establishment of a Murine Pro-acinar Cell Line to Characterize Roles for FGF2 and α3β1 Integrins in Regulating Pro-acinar Characteristics
Renée F. Thiemann, Deirdre A. Nelson, C. Michael DiPersio, Melinda Larsen, Susan E. LaFlamme
Sci Rep. 2019; 9: 10984. Published online 2019 Jul 29. doi: 10.1038/s41598-019-47387-y
PMCID:
PMC6662831
AbstractArticlePDF–3.3M
14.
Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo
Veronika Ramovs, Pablo Secades, Ji-Ying Song, Bram Thijssen, Maaike Kreft, Arnoud Sonnenberg
Breast Cancer Res. 2019; 21: 63. Published online 2019 May 17. doi: 10.1186/s13058-019-1146-8
PMCID:
PMC6525362
AbstractArticlePDF–6.4M
15.
The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth
Eugenia M. Yazlovitskaya, Olga Viquez, Tianxiang Tu, Adele De Arcangelis, Elisabeth Georges-Labouesse, Arnoud Sonnenberg, Ambra Pozzi, Roy Zent
Matrix Biol. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Matrix Biol. 2019 Apr; 77: 101–116. Published online 2018 Sep 4. doi: 10.1016/j.matbio.2018.08.010
PMCID:
PMC6399080
AbstractArticlePDF–2.8M
16.
An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri
Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3
PMCID:
PMC6381143
AbstractArticlePDF–10M
17.
WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development
Akiko Suzuki, Ryohei Minamide, Junichi Iwata
Development. 2018 Dec 1; 145(23): dev168351. Published online 2018 Nov 27. doi: 10.1242/dev.168351
PMCID:
PMC6288386
AbstractArticle
18.
Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion
Jingyuan Li, Yuan Yuan, Jinzhi He, Jifan Feng, Xia Han, Junjun Jing, Thach-Vu Ho, Jian Xu, Yang Chai
Dev Biol. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Dev Biol. 2018 Sep 1; 441(1): 191–203. Published online 2018 Jul 5. doi: 10.1016/j.ydbio.2018.07.003
PMCID:
PMC6152919
AbstractArticlePDF–3.8M
19.
CNS Neurons Deposit Laminin a5 to Stabilize Synapses
Mitchell H. Omar, Meghan Kerrisk Campbell, Xiao Xiao, Qiaonan Zhong, William J. Brunken, Jeffrey H. Miner, Charles A. Greer, Anthony J. Koleske
Cell Rep. Author manuscript; available in PMC 2018 Jan 22.
Published in final edited form as: Cell Rep. 2017 Oct 31; 21(5): 1281–1292. doi: 10.1016/j.celrep.2017.10.028
PMCID:
PMC5776391
AbstractArticlePDF–2.4M
20.
The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain
Michael R. Dohn, Christopher G. Kooker, Lisa Bastarache, Tammy Jessen, Capria Rinaldi, Seth Varney, Matthew D. Mazalouskas, Hope Pan, Kendra H. Oliver, Digna R. Velez Edwards, James S. Sutcliffe, Joshua C. Denny, Ana M.D. Carneiro
J Neurosci. 2017 Nov 15; 37(46): 11271–11284. doi: 10.1523/JNEUROSCI.1482-17.2017
PMCID:
PMC5688530
AbstractArticlePDF–2.5M

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