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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 89720932.

A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice

Junsong Zhou, Yi Wu, Lubica Rauova, Gavin Koma, Lu Wang, Mortimer Poncz, Hong Li, Tong Liu, Karen P. Fong, Joel S. Bennett, Satya P. Kunapuli, David W. Essex

Blood. 2022 Mar 31; 139(13): 2050–2065. doi: 10.1182/blood.2021012055

PMCID:: PMC8972093

Abstract Article

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 79197224.

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts

Yen-Ting Chen, Pei-Yu Jhao, Chen-Ting Hung, Yueh-Feng Wu, Sung-Jan Lin, Wen-Chih Chiang, Shuei-Liong Lin, Kai-Chien Yang

J Clin Invest. 2021 Mar 1; 131(5): e143645. Published online 2021 Mar 1. doi: 10.1172/JCI143645

PMCID:: PMC7919722

Abstract Article PDF–30M

Select item 74499705.

Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization

Tzu-Han Lee, Chih-Fan Yeh, Ying-Tung Lee, Ying-Chun Shih, Yen-Ting Chen, Chen-Ting Hung, Ming-Yi You, Pei-Chen Wu, Tzu-Pin Shentu, Ru-Ting Huang, Yu-Shan Lin, Yueh-Feng Wu, Sung-Jan Lin, Frank-Leigh Lu, Po-Nien Tsao, Tzu-Hung Lin, Shen-Chuan Lo, Yi-Shuan Tseng, Wan-Lin Wu, Chiung-Nien Chen, Chau-Chung Wu, Shuei-Liong Lin, Anne I. Sperling, Robert D. Guzy, Yun Fang, Kai-Chien Yang

Nat Commun. 2020; 11: 4254. Published online 2020 Aug 26. doi: 10.1038/s41467-020-18047-x

PMCID:: PMC7449970

Abstract Article PDF–6.3M

Select item 63466856.

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells

Farzad Asadi, Savita Dhanvantari

Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792

PMCID:: PMC6346685

Abstract Article PDF–3.6M

Select item 62980407.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 58990168.

Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation

Ying-Chun Shih, Chao-Ling Chen, Yan Zhang, Rebecca L. Mellor, Evelyn M. Kanter, Yun Fang, Hua-Chi Wang, Chen-Ting Hung, Jing-Yi Nong, Hui-Ju Chen, Tzu-Han Lee, Yi-Shuan Tseng, Chiung-Nien Chen, Chau-Chung Wu, Shuei-Liong Lin, Kathryn A. Yamada, Jeanne M. Nerbonne, Kai-Chien Yang

Circ Res. Author manuscript; available in PMC 2019 Apr 13.

Published in final edited form as: Circ Res. 2018 Apr 13; 122(8): 1052–1068. Published online 2018 Mar 13. doi: 10.1161/CIRCRESAHA.117.312130

PMCID:: PMC5899016

Abstract Article PDF–1.0M

Select item 53812269.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 497021311.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 407349412.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 396495513.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 354114814.

Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis

Lin Wang, Yabing Zheng, Hengwei Xu, Xinfeng Yan, Xiaotian Chang

PLoS One. 2013; 8(1): e53301. Published online 2013 Jan 9. doi: 10.1371/journal.pone.0053301

PMCID:: PMC3541148

Abstract Article PDF–1.9M

Select item 331417915.

Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation

Reena Singh, Willem M. Hoogaars, Phil Barnett, Thomas Grieskamp, M. Sameer Rana, Henk Buermans, Henner F. Farin, Marianne Petry, Todd Heallen, James F. Martin, Antoon F. M. Moorman, Peter A. C. ‘t Hoen, Andreas Kispert, Vincent M. Christoffels

Cell Mol Life Sci. 2012 Apr; 69(8): 1377–1389. Published online 2011 Dec 1. doi: 10.1007/s00018-011-0884-2

PMCID:: PMC3314179

Abstract Article PDF–3.2M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 281013618.

BMP-6 is a key endogenous regulator of hepcidin expression and iron metabolism

Billy Andriopoulos, Jr., Elena Corradini, Yin Xia, Sarah A. Faasse, Shanzhuo Chen, Lovorka Grgurevic, Mitchell D. Knutson, Antonello Pietrangelo, Slobodan Vukicevic, Herbert Y. Lin, Jodie L. Babitt

Nat Genet. Author manuscript; available in PMC 2010 Jan 22.

Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 482–487. Published online 2009 Mar 1. doi: 10.1038/ng.335

PMCID:: PMC2810136

Abstract Article PDF–2.2M

Select item 260547919.

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives

Owen J Tamplin, Doris Kinzel, Brian J Cox, Christine E Bell, Janet Rossant, Heiko Lickert

BMC Genomics. 2008; 9: 511. Published online 2008 Oct 30. doi: 10.1186/1471-2164-9-511

PMCID:: PMC2605479

Abstract Article PDF–1.7M

Select item 154073120.

A RecA-mediated exon profiling method

Yuki Hasegawa, Shiro Fukuda, Kazuro Shimokawa, Shinji Kondo, Norihiro Maeda, Yoshihide Hayashizaki

Nucleic Acids Res. 2006; 34(13): e97. Published online 2006 Aug 8. doi: 10.1093/nar/gkl497

PMCID:: PMC1540731

Abstract Article PDF–366K

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