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Select item 112412341.

Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord

Anutosh Roy, Gisela Segond von Banchet, Fátima Gimeno-Ferrer, Christian König, Annett Eitner, Andrea Ebersberger, Matthias Ebbinghaus, Johannes Leuchtweis, Hans-Georg Schaible

Int J Mol Sci. 2024 Jul; 25(13): 7168. Published online 2024 Jun 28. doi: 10.3390/ijms25137168

PMCID:: PMC11241234

Abstract Article PDF–4.3M

Select item 112138712.

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Nat Commun. 2024; 15: 5489. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49449-w

PMCID:: PMC11213871

Abstract Article PDF–7.1M

Select item 111865053.

In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss

Sarath Vijayakumar, Joseph A. DiGuiseppi, Parinaz Jila Dabestani, William G. Ryan, Rene Vielman Quevedo, Yuju Li, Jack Diers, Shu Tu, Jonathan Fleegel, Cassidy Nguyen, Lauren M. Rhoda, Ali Sajid Imami, Abdul-Rizaq Ali Hamoud, Sándor Lovas, Robert E. McCullumsmith, Marisa Zallocchi, Jian Zuo

Sci Adv. 2024 Jun 21; 10(25): eadk2299. Published online 2024 Jun 19. doi: 10.1126/sciadv.adk2299

PMCID:: PMC11186505

Abstract Article PDF–6.3M

Select item 111590334.

Occurrence of mutations in the epidermal growth factor receptor gene in X‐ray‐induced rat lung tumors

Tsukasa Kitahashi, Mami Takahashi, Yutaka Yamada, Yoichi Oghiso, Masanao Yokohira, Katsumi Imaida, Masahiro Tsutsumi, Nobuo Takasuka, Takashi Sugimura, Keiji Wakabayashi

Cancer Sci. 2008 Feb; 99(2): 241–245. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2008.00680.x

PMCID:: PMC11159033

Abstract Article PDF–153K

Select item 111587735.

Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP‐C promoter

Kadoaki Ohashi, Kammei Rai, Yoshiro Fujiwara, Masahiro Osawa, Seiki Hirano, Katsuyoshi Takata, Eisaku Kondo, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura

Cancer Sci. 2008 Sep; 99(9): 1747–1753. Published online 2008 Jun 28. doi: 10.1111/j.1349-7006.2008.00875.x

PMCID:: PMC11158773

Abstract Article PDF–690K

Select item 111315496.

Interaction between PGE₂ and EGF receptor through MAPKs in mouse embryonic stem cell proliferation

S. P. Yun, M. Y. Lee, J. M. Ryu, H. J. Han

Cell Mol Life Sci. 2009 May; 66(9): 1603–1616. Published online 2009 Mar 27. doi: 10.1007/s00018-009-9076-8

PMCID:: PMC11131549

Abstract Article PDF–2.3M

Select item 110980997.

A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex

Xiaoyi G. Liang, Kendy Hoang, Brandon L. Meyerink, Pratiksha Kc, Kitt Paraiso, Li Wang, Ian R. Jones, Yue Zhang, Sol Katzman, Thomas S. Finn, Jeremiah Tsyporin, Fangyuan Qu, Zhaoxu Chen, Axel Visel, Arnold Kriegstein, Yin Shen, Louis-Jan Pilaz, Bin Chen

Proc Natl Acad Sci U S A. 2024 May 14; 121(20): e2321711121. Published online 2024 May 7. doi: 10.1073/pnas.2321711121

PMCID:: PMC11098099

Abstract Article PDF–16M

Select item 109371568.

Growth/differentiation factor 15 controls ependymal and stem cell number in the V-SVZ

Katja Baur, Carmen Carrillo-García, Şeydanur Şan, Manja von Hahn, Jens Strelau, Gabriele Hölzl-Wenig, Claudia Mandl, Francesca Ciccolini

Stem Cell Reports. 2024 Mar 12; 19(3): 351–365. Published online 2024 Feb 15. doi: 10.1016/j.stemcr.2024.01.008

PMCID:: PMC10937156

Abstract Article PDF–8.0M

Select item 109183469.

The miR-7/EGFR axis controls the epithelial cell immunomodulation and regeneration and orchestrates the pathology in inflammatory bowel disease

Juanjuan Zhao, Mengmeng Guo, Yaping Yan, Ya Wang, Xu Zhao, Jing Yang, Jing Chen, Chao Chen, Lin Tang, Wenhuan Zeng, Yiting Liu, Ming Qin, Ya Zhou, Lin Xu

J Adv Res. 2024 Mar; 57: 119–134. Published online 2023 Apr 23. doi: 10.1016/j.jare.2023.04.011

PMCID:: PMC10918346

Abstract Article PDF–8.8M

Select item 1091766010.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1076267711.

BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period

Zhenmeiyu Li, Guoping Liu, Lin Yang, Mengge Sun, Zhuangzhi Zhang, Zhejun Xu, Yanjing Gao, Xin Jiang, Zihao Su, Xiaosu Li, Zhengang Yang

Protein Cell. 2024 Jan; 15(1): 21–35. Published online 2023 Jun 10. doi: 10.1093/procel/pwad036

PMCID:: PMC10762677

Abstract Article PDF–55M

Select item 1075875312.

Myeloid cell-specific deletion of epidermal growth factor receptor aggravates acute cardiac injury

Ama D. Okyere, Tapas K. Nayak, Viren Patwa, David Teplitsky, Erin McEachern, Rhonda L. Carter, Heli Xu, Erhe Gao, Yan Zhou, Douglas G. Tilley

Clin Sci (Lond) Author manuscript; available in PMC 2024 Jan 2.

Published in final edited form as: Clin Sci (Lond). 2023 Oct 11; 137(19): 1513–1531. doi: 10.1042/CS20230804

PMCID:: PMC10758753

Abstract Article PDF–2.6M

Select item 1068784513.

Targeting epidermal growth factor receptor to recruit newly generated neuroblasts in cortical brain injuries

Ricardo Gómez-Oliva, Noelia Geribaldi-Doldán, Samuel Domínguez-García, Ricardo Pardillo-Díaz, Sergio Martínez-Ortega, José M. Oliva-Montero, Patricia Pérez-García, Francisco J. García-Cózar, Juan P. Muñoz-Miranda, Ismael Sánchez-Gomar, Pedro Nunez-Abades, Carmen Castro

J Transl Med. 2023; 21: 867. Published online 2023 Nov 30. doi: 10.1186/s12967-023-04707-1

PMCID:: PMC10687845

Abstract Article PDF–7.9M

Select item 1067158614.

Epidermal Growth Factor Receptors in Vascular Endothelial Cells Contribute to Functional Hyperemia in the Brain

Hannah R. Ferris, Nathan C. Stine, David C. Hill-Eubanks, Mark T. Nelson, George C. Wellman, Masayo Koide

Int J Mol Sci. 2023 Nov; 24(22): 16284. Published online 2023 Nov 14. doi: 10.3390/ijms242216284

PMCID:: PMC10671586

Abstract Article PDF–2.3M

Select item 1064588715.

Epidermal growth factor receptor activation is essential for kidney fibrosis development

Shirong Cao, Yu Pan, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Yinqiu Wang, Jiaqi Tang, Aolei Niu, Sarah Abu Kar, Mengdi Jiang, Wentian Luo, Xinyu Dong, Xiaofeng Fan, Suwan Wang, Matthew H. Wilson, Agnes Fogo, Ming-Zhi Zhang, Raymond C. Harris

Nat Commun. 2023; 14: 7357. Published online 2023 Nov 14. doi: 10.1038/s41467-023-43226-x

PMCID:: PMC10645887

Abstract Article PDF–5.9M

Select item 1064166616.

A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways

Bradley R. Groveman, Benjamin Schwarz, Eric Bohrnsen, Simote T. Foliaki, James A. Carroll, Aleksandar R. Wood, Catharine M. Bosio, Cathryn L. Haigh

J Biol Chem. 2023 Nov; 299(11): 105319. Published online 2023 Oct 4. doi: 10.1016/j.jbc.2023.105319

PMCID:: PMC10641666

Abstract Article PDF–4.6M

Select item 1062949917.

The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells

Seiichi Koike, Kazuko Keino-Masu, Yoko Tanimoto, Satoru Takahashi, Masayuki Masu

Biol Open. 2023 Nov 15; 12(11): bio060081. Published online 2023 Oct 30. doi: 10.1242/bio.060081

PMCID:: PMC10629499

Abstract Article PDF–3.4M

Select item 1062012318.

Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma

Kathrin Hedegger, Andreas Blutke, Theresa Hommel, Kerstin E. Auer, Nishanth B. Nataraj, Moshit Lindzen, Yosef Yarden, Maik Dahlhoff

Mol Oncol. 2023 Nov; 17(11): 2415–2431. Published online 2023 Jul 14. doi: 10.1002/1878-0261.13473

PMCID:: PMC10620123

Abstract Article PDF–4.1M

Select item 1061606519.

The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes

Arielle Raugh, Yi Jing, Matthew L. Bettini, Maria Bettini

Sci Rep. 2023; 13: 18653. Published online 2023 Oct 30. doi: 10.1038/s41598-023-45738-4

PMCID:: PMC10616065

Abstract Article PDF–1.6M

Select item 1054480320.

Novel EGFR-Mutant Mouse Models of Lung Adenocarcinoma Reveal Adaptive Immunity Requirement for Durable Osimertinib Response

Emily K Kleczko, Anh T Le, Trista K Hinz, Teresa T Nguyen, Andre Navarro, Cheng-Jun Hu, Ana M. Selman, Eric T Clambey, Daniel T Merrick, Sizhao Lu, Mary Weiser-Evans, Raphael A Nemenoff, Lynn E Heasley

Cancer Lett. Author manuscript; available in PMC 2023 Sep 29.

Published in final edited form as: Cancer Lett. 2023 Mar 1; 556: 216062. Published online 2023 Jan 16. doi: 10.1016/j.canlet.2023.216062

PMCID:: PMC10544803

Abstract Article PDF–1.0M

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