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Select item 107535871.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 105057322.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 100177033.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 99505154.

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age

Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri

Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770

PMCID:: PMC9950515

Abstract Article PDF–4.2M

Select item 96553135.

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate

Nour Abou Nader, Amélie Ménard, Adrien Levasseur, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer

Int J Mol Sci. 2022 Nov; 23(21): 13585. Published online 2022 Nov 5. doi: 10.3390/ijms232113585

PMCID:: PMC9655313

Abstract Article PDF–4.1M

Select item 93380406.

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat

Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1

PMCID:: PMC9338040

Abstract Article PDF–11M

Select item 92003077.

Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice

Alejo Torres-Cano, Rosa Portella-Fortuny, Claudia Müller-Sánchez, Sonia Porras-Marfil, Marina Ramiro-Pareta, You-Ying Chau, Manuel Reina, Francesc X. Soriano, Ofelia M. Martínez-Estrada

PLoS Genet. 2022 Jun; 18(6): e1010240. Published online 2022 Jun 15. doi: 10.1371/journal.pgen.1010240

PMCID:: PMC9200307

Abstract Article PDF–4.3M

Select item 85116598.

Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis^†

Shu-Yun Li, Xiaowei Gu, Anna Heinrich, Emily G Hurley, Blanche Capel, Tony DeFalco

Biol Reprod. 2021 Oct; 105(4): 958–975. Published online 2021 May 18. doi: 10.1093/biolre/ioab098

PMCID:: PMC8511659

Abstract Article PDF–2.6M

Select item 82998669.

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility and metabolic homeostasis in female mice

Emmi Rotgers, Barbara Nicol, Karina Rodriguez, Saniya Rattan, Jodi A. Flaws, Humphrey Hung-Chang Yao

FASEB J. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21770. doi: 10.1096/fj.202100304R

PMCID:: PMC8299866

Abstract Article PDF–2.6M

Select item 631083410.

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex

Mickael Mathieu, Coralie Drelon, Stéphanie Rodriguez, Houda Tabbal, Amandine Septier, Christelle Damon-Soubeyrand, Typhanie Dumontet, Annabel Berthon, Isabelle Sahut-Barnola, Cyril Djari, Marie Batisse-Lignier, Jean-Christophe Pointud, Damien Richard, Gwenneg Kerdivel, Marie-Ange Calméjane, Valentina Boeva, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val

Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12265–E12274. Published online 2018 Dec 12. doi: 10.1073/pnas.1809185115

PMCID:: PMC6310834

Abstract Article PDF–2.4M

Select item 620772611.

A perivascular niche for multipotent progenitors in the fetal testis

Deepti L. Kumar, Tony DeFalco

Nat Commun. 2018; 9: 4519. Published online 2018 Oct 30. doi: 10.1038/s41467-018-06996-3

PMCID:: PMC6207726

Abstract Article PDF–6.5M

Select item 618963212.

Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis

Qing Wen, Qiao-Song Zheng, Xi-Xia Li, Zhao-Yuan Hu, Fei Gao, C. Yan Cheng, Yi-Xun Liu

Am J Physiol Endocrinol Metab. 2014 Dec 15; 307(12): E1131–E1143. Published online 2014 Oct 21. doi: 10.1152/ajpendo.00425.2014

PMCID:: PMC6189632

Abstract Article

Select item 618163913.

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

Tatiana V. Novoselova, Mashal Hussain, Peter J. King, Leonardo Guasti, Louise A. Metherell, Marika Charalambous, Adrian J. L. Clark, Li F. Chan

FASEB J. 2018 Nov; 32(11): 6186–6196. Published online 2018 Jun 7. doi: 10.1096/fj.201701274RR

PMCID:: PMC6181639

Abstract Article

Select item 613744914.

Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis

Elena M. Kaftanovskaya, Carolina Lopez, Lydia Ferguson, Courtney Myhr, Alexander I. Agoulnik

FASEB J. 2015 Jun; 29(6): 2327–2337. Published online 2015 Feb 20. doi: 10.1096/fj.14-263632

PMCID:: PMC6137449

Abstract Article

Select item 576430415.

MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice

Hossam H. Shawki, Hisashi Oishi, Toshiaki Usui, Yu Kitadate, Walaa A. Basha, Ahmed M. Abdellatif, Kazunori Hasegawa, Risa Okada, Keiji Mochida, Hany A. El-Shemy, Masafumi Muratani, Atsuo Ogura, Shosei Yoshida, Satoru Takahashi

PLoS One. 2018; 13(1): e0190800. Published online 2018 Jan 11. doi: 10.1371/journal.pone.0190800