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Items: 1 to 20 of 27

1.
Immune sensing of food allergens promotes avoidance behaviour
Esther B. Florsheim, Nathaniel D. Bachtel, Jaime L. Cullen, Bruna G. C. Lima, Mahdieh Godazgar, Fernando Carvalho, Carolina P. Chatain, Marcelo R. Zimmer, Cuiling Zhang, Gregory Gautier, Pierre Launay, Andrew Wang, Marcelo O. Dietrich, Ruslan Medzhitov
Nature. 2023; 620(7974): 643–650. Published online 2023 Jul 12. doi: 10.1038/s41586-023-06362-4
PMCID:
PMC10432274
AbstractArticlePDF–7.0M
2.
Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation
Saltanat Ualiyeva, Evan Lemire, Evelyn C. Aviles, Caitlin Wong, Amelia A. Boyd, Juying Lai, Tao Liu, Ichiro Matsumoto, Nora A. Barrett, Joshua A. Boyce, Adam L. Haber, Lora G. Bankova
Sci Immunol. Author manuscript; available in PMC 2022 Jun 24.
Published in final edited form as: Sci Immunol. 2021 Dec 24; 6(66): eabj0474. Published online 2021 Dec 24. doi: 10.1126/sciimmunol.abj0474
PMCID:
PMC8750919
AbstractArticlePDF–2.7M
3.
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25–producing airway brush cells leading to type 2 inflammation
Lora G. Bankova, Daniel F. Dwyer, Eri Yoshimoto, Saltanat Ualiyeva, John W. McGinty, Hannah Raff, Jakob von Moltke, Yoshihide Kanaoka, K. Frank Austen, Nora A. Barrett
Sci Immunol. Author manuscript; available in PMC 2019 Jun 30.
Published in final edited form as: Sci Immunol. 2018 Oct 5; 3(28): eaat9453. doi: 10.1126/sciimmunol.aat9453
PMCID:
PMC6599626
AbstractArticlePDF–2.7M
4.
Inhibition of 5-lipoxygenase decreases renal fibrosis and progression of chronic kidney disease
John R. Montford, Colin Bauer, Evgenia Dobrinskikh, Katharina Hopp, Moshe Levi, Mary Weiser-Evans, Raphael Nemenoff, Seth B. Furgeson
Am J Physiol Renal Physiol. 2019 Apr 1; 316(4): F732–F742. Published online 2019 Jan 16. doi: 10.1152/ajprenal.00262.2018
PMCID:
PMC6483031
AbstractArticle
5.
Type 2 cysteinyl leukotriene receptors drive IL-33-dependent type 2 immunopathology and aspirin sensitivity
Tao Liu, Nora A. Barrett, Yoshihide Kanaoka, Eri Yoshimoto, Denise Garofalo, Haley Cirka, Chunli Feng, Joshua A. Boyce
J Immunol. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: J Immunol. 2018 Feb 1; 200(3): 915–927. Published online 2017 Dec 27. doi: 10.4049/jimmunol.1700603
PMCID:
PMC5780246
AbstractArticlePDF–1.2M
6.
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s
Jakob von Moltke, Claire E. O’Leary, Nora A. Barrett, Yoshihide Kanaoka, K. Frank Austen, Richard M. Locksley
J Exp Med. 2017 Jan; 214(1): 27–37. doi: 10.1084/jem.20161274
PMCID:
PMC5206504
AbstractArticlePDF–1.7M
7.
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity
Shabbir Ahmad, A. Jimmy Ytterberg, Madhuranayaki Thulasingam, Fredrik Tholander, Tomas Bergman, Roman Zubarev, Anders Wetterholm, Agnes Rinaldo-Matthis, Jesper Z. Haeggström
J Biol Chem. 2016 Aug 26; 291(35): 18410–18418. Published online 2016 Jun 30. doi: 10.1074/jbc.M116.735647
PMCID:
PMC5000086
AbstractArticlePDF–1.3M
8.
Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein–coupled receptor, GPR99
Lora G. Bankova, Juying Lai, Eri Yoshimoto, Joshua A. Boyce, K. Frank Austen, Yoshihide Kanaoka, Nora A. Barrett
Proc Natl Acad Sci U S A. 2016 May 31; 113(22): 6242–6247. Published online 2016 May 16. doi: 10.1073/pnas.1605957113
PMCID:
PMC4896673
AbstractArticlePDF–1.0M
9.
Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment
Joanna M. Poczobutt, Teresa T. Nguyen, Dwight Hanson, Howard Li, Trisha R. Sippel, Mary C. M. Weiser-Evans, Miguel Gijon, Robert C. Murphy, Raphael A. Nemenoff
J Immunol. 2016 Jan 15; 196(2): 891–901. Published online 2015 Dec 11. doi: 10.4049/jimmunol.1501648
PMCID:
PMC4705594
AbstractArticlePDF–1.3M
10.
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis
Yoshitaka Taketomi, Noriko Ueno, Takumi Kojima, Hiroyasu Sato, Remi Murase, Kei Yamamoto, Satoshi Tanaka, Mariko Sakanaka, Masanori Nakamura, Yasumasa Nishito, Momoko Kawana, Naotomo Kambe, Kazutaka Ikeda, Ryo Taguchi, Satoshi Nakamizo, Kenji Kabashima, Michael H. Gelb, Makoto Arita, Takehiko Yokomizo, Motonao Nakamura, Kikuko Watanabe, Hiroyuki Hirai, Masataka Nakamura, Yoshimichi Okayama, Chisei Ra, Kosuke Aritake, Yoshihiro Urade, Kazushi Morimoto, Yukihiko Sugimoto, Takao Shimizu, Shuh Narumiya, Shuntaro Hara, Makoto Murakami
Nat Immunol. Author manuscript; available in PMC 2014 Jun 21.
Published in final edited form as: Nat Immunol. 2013 Jun; 14(6): 554–563. Published online 2013 Apr 28. doi: 10.1038/ni.2586
PMCID:
PMC4065307
AbstractArticlePDF–1.0M
11.
Structure and Inhibition of Mouse Leukotriene C4 Synthase
Damian Niegowski, Thea Kleinschmidt, Shabbir Ahmad, Abdul Aziz Qureshi, Michaela Mårback, Agnes Rinaldo-Matthis, Jesper Z. Haeggström
PLoS One. 2014; 9(5): e96763. Published online 2014 May 8. doi: 10.1371/journal.pone.0096763
Correction in:
PLoS One. 2014; 9(6): e99747.
PMCID:
PMC4014545
AbstractArticlePDF–601K
12.
5-Lipoxygenase Metabolite 4-HDHA Is a Mediator of the Antiangiogenic Effect of ω-3 Polyunsaturated Fatty Acids
Przemyslaw Sapieha, Andreas Stahl, Jing Chen, Molly R. Seaward, Keirnan L. Willett, Nathan M. Krah, Roberta J. Dennison, Kip M. Connor, Christopher M. Aderman, Elvira Liclican, Arianna Carughi, Dalia Perelman, Yoshihide Kanaoka, John Paul SanGiovanni, Karsten Gronert, Lois E. H. Smith
Sci Transl Med. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Sci Transl Med. 2011 Feb 9; 3(69): 69ra12. doi: 10.1126/scitranslmed.3001571
PMCID:
PMC3711031
AbstractArticlePDF–3.5M
13.
Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells
Nora A. Barrett, Akiko Maekawa, Opu M. Rahman, K. Frank Austen, Yoshihide Kanaoka
J Immunol. Author manuscript; available in PMC 2013 Jun 14.
Published in final edited form as: J Immunol. 2009 Jan 15; 182(2): 1119–1128. doi: 10.4049/jimmunol.182.2.1119
PMCID:
PMC3682801
AbstractArticlePDF–3.2M
14.
Cysteinyl Leukotriene 2 Receptor on Dendritic Cells Negatively Regulates Ligand-Dependent Allergic Pulmonary Inflammation
Nora A. Barrett, James M. Fernandez, Akiko Maekawa, Wei Xing, Li Li, Matthew W. Parsons, K. Frank Austen, Yoshihide Kanaoka
J Immunol. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: J Immunol. 2012 Nov 1; 189(9): 4556–4565. Published online 2012 Sep 21. doi: 10.4049/jimmunol.1201865
PMCID:
PMC3478400
AbstractArticlePDF–2.8M
15.
Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis
Michiko K. Oyoshi, Rui He, Yoshihide Kanaoka, Abdallah ElKhal, Seiji Kawamoto, Christopher N. Lewis, K. Frank Austen, Raif S. Geha
Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13): 4992–4997. Published online 2012 Mar 13. doi: 10.1073/pnas.1203127109
PMCID:
PMC3323994
AbstractArticlePDF–1.0M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
Nora A. Barrett, Opu M. Rahman, James M. Fernandez, Matthew W. Parsons, Wei Xing, K. Frank Austen, Yoshihide Kanaoka
J Exp Med. 2011 Mar 14; 208(3): 593–604. doi: 10.1084/jem.20100793
PMCID:
PMC3058587
AbstractArticlePDF–1.6M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Mast Cell Protease 5 Mediates Ischemia-Reperfusion Injury of Mouse Skeletal Muscle
J. Pablo Abonia, Daniel S. Friend, William G. Austen, Jr., Francis D. Moore, Jr., Michael C. Carroll, Rodney Chan, Jalil Afnan, Alison Humbles, Craig Gerard, Pamela Knight, Yoshihide Kanaoka, Shinsuke Yasuda, Nasa Morokawa, K. Frank Austen, Richard L. Stevens, Michael F. Gurish
J Immunol. Author manuscript; available in PMC 2010 Oct 7.
Published in final edited form as: J Immunol. 2005 Jun 1; 174(11): 7285–7291. doi: 10.4049/jimmunol.174.11.7285
PMCID:
PMC2951006
AbstractArticlePDF–703K
20.
Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow
Tulio Queto, Maria I. Gaspar-Elsas, Daniela Masid-de-Brito, Zilton F. M. Vasconcelos, Fausto K. Ferraris, Carmen Penido, Fernando Q. Cunha, Yoshihide Kanaoka, Bing K. Lam, Pedro Xavier-Elsas
J Leukoc Biol. 2010 May; 87(5): 885–893. Published online 2010 Mar 10. doi: 10.1189/jlb.1108709
PMCID:
PMC2858675
AbstractArticle

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