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Items: 1 to 20 of 111

1.
Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells
Mehdi Amiri, Stephen J. Kiniry, Anthony P. Possemato, Niaz Mahmood, Tayebeh Basiri, Catherine R. Dufour, Negar Tabatabaei, Qiyun Deng, Michael A. Bellucci, Keerthana Harwalkar, Matthew P. Stokes, Vincent Giguère, Randal J. Kaufman, Yojiro Yamanaka, Pavel V. Baranov, Soroush Tahmasebi, Nahum Sonenberg
Cell Rep. Author manuscript; available in PMC 2024 Mar 25.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113615. Published online 2023 Dec 29. doi: 10.1016/j.celrep.2023.113615
PMCID:
PMC10962698
AbstractArticlePDF–2.5M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
4.
DELE1 is protective for mitochondrial cardiomyopathy
Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.
Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003
PMCID:
PMC10387237
AbstractArticlePDF–661K
5.
SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology
Kristine E. Zengeler, Daniel A. Shapiro, Katherine R. Bruch, Catherine R. Lammert, Hannah Ennerfelt, John R. Lukens
Brain Behav Immun. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Brain Behav Immun. 2023 Feb; 108: 80–97. Published online 2022 Nov 4. doi: 10.1016/j.bbi.2022.10.024
PMCID:
PMC10291741
AbstractArticlePDF–2.7M
6.
eIF2α incites photoreceptor cell and retina damage by all-trans-retinal
Danxue He, Lei Tao, Binxiang Cai, Xiangjun Chen, Yan Wang, Shiying Li, Chunyan Liao, Yuling Chen, Jingmeng Chen, Zuguo Liu, Yalin Wu
J Biol Chem. 2023 May; 299(5): 104686. Published online 2023 Apr 7. doi: 10.1016/j.jbc.2023.104686
PMCID:
PMC10193240
AbstractArticlePDF–4.6M
7.
Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee
Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y
PMCID:
PMC9968297
AbstractArticlePDF–4.4M
8.
Stress-mediated attenuation of translation undermines T-cell activity in cancer
Brian P. Riesenberg, Elizabeth G. Hunt, Megan D. Tennant, Katie E. Hurst, Alex M. Andrews, Lee R. Leddy, David M. Neskey, Elizabeth G. Hill, Guillermo O. Rangel Rivera, Chrystal M. Paulos, Peng Gao, Jessica E. Thaxton
Cancer Res. Author manuscript; available in PMC 2023 Jun 2.
Published in final edited form as: Cancer Res. 2022 Dec 2; 82(23): 4386–4399. doi: 10.1158/0008-5472.CAN-22-1744
PMCID:
PMC9722626
AbstractArticlePDF–2.3M
9.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
10.
Amyloid beta induces Fmr1‐dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2
Simon Lizarazo, Yeeun Yook, Nien‐Pei Tsai
J Cell Physiol. 2022 Jul; 237(7): 2929–2942. Published online 2022 Apr 17. doi: 10.1002/jcp.30754
PMCID:
PMC9283232
AbstractArticlePDF–4.0M
11.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation
Junchao Shi, Zi Li, Rongyi Xu, Jing Zhang, Qianyu Zhou, Rui Gao, Huijun Lu, Yungang Lan, Kui Zhao, Hongbin He, Feng Gao, Wenqi He
J Virol. 2022 Jan; 96(1): e01695-21. Prepublished online 2021 Oct 13. Published online 2022 Jan 12. doi: 10.1128/JVI.01695-21
PMCID:
PMC8754228
AbstractArticlePDF–6.3M
12.
Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function
Francesco Longo, Maria Mancini, Pierre L. Ibraheem, Sameer Aryal, Caterina Mesini, Jyoti C. Patel, Elena Penhos, Nazia Rahman, Maggie Mamcarz, Emanuela Santini, Margaret E. Rice, Eric Klann
Mol Psychiatry. Author manuscript; available in PMC 2022 Jan 16.
Published in final edited form as: Mol Psychiatry. 2021 Nov; 26(11): 6427–6450. Published online 2021 Apr 20. doi: 10.1038/s41380-021-01099-w
PMCID:
PMC8526653
AbstractArticlePDF–2.5M
13.
Cholinergic neurons engage the integrated stress response for dopamine modulation and skill learning
Ashley R. Helseth, Ricardo Hernandez-Martinez, Victoria L. Hall, Matthew L. Oliver, Brandon D. Turner, Zachary F. Caffall, Joseph E. Rittiner, Miranda K. Shipman, Connor S. King, Viviana Gradinaru, Charles Gerfen, Mauro Costa-Mattioli, Nicole Calakos
Science. Author manuscript; available in PMC 2021 Sep 22.
Published in final edited form as: Science. 2021 Apr 23; 372(6540): eabe1931. doi: 10.1126/science.abe1931
PMCID:
PMC8457366
AbstractArticlePDF–1.8M
14.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
15.
Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy
Mariapaola Sidoli, Chelsey B. Reed, Cristina Scapin, Pablo Paez, Douglas R. Cavener, Randal J. Kaufman, Maurizio D'Antonio, M. Laura Feltri, Lawrence Wrabetz
J Neurosci. 2021 May 19; 41(20): 4536–4548. doi: 10.1523/JNEUROSCI.2384-20.2021
PMCID:
PMC8152608
AbstractArticlePDF–5.3M
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
eIF2α controls memory consolidation via excitatory and somatostatin neurons
Vijendra Sharma, Rapita Sood, Abdessattar Khlaifia, Mohammad Javad Eslamizade, Tzu-Yu Hung, Danning Lou, Azam Asgarihafshejani, Maya Lalzar, Stephen J. Kiniry, Matthew P. Stokes, Noah Cohen, Alissa J. Nelson, Kathryn Abell, Anthony P. Possemato, Shunit Gal-Ben-Ari, Vinh T. Truong, Peng Wang, Adonis Yiannakas, Fatemeh Saffarzadeh, A. Claudio Cuello, Karim Nader, Randal J. Kaufman, Mauro Costa-Mattioli, Pavel V. Baranov, Albert Quintana, Elisenda Sanz, Arkady Khoutorsky, Jean-Claude Lacaille, Kobi Rosenblum, Nahum Sonenberg
Nature. Author manuscript; available in PMC 2021 Oct 7.
Published in final edited form as: Nature. 2020 Oct; 586(7829): 412–416. Published online 2020 Oct 7. doi: 10.1038/s41586-020-2805-8
PMCID:
PMC7874887
AbstractArticlePDF–5.3M
18.
Maternal Immune Activation in Mice Disrupts Proteostasis in the Fetal Brain
Brian T. Kalish, Eunha Kim, Benjamin Finander, Erin E. Duffy, Hyunju Kim, Casey K. Gilman, Yeong Shin Yim, Lilin Tong, Randal J. Kaufman, Eric C. Griffith, Gloria B. Choi, Michael E. Greenberg, Jun R. Huh
Nat Neurosci. Author manuscript; available in PMC 2021 Jun 23.
Published in final edited form as: Nat Neurosci. 2021 Feb; 24(2): 204–213. Published online 2020 Dec 23. doi: 10.1038/s41593-020-00762-9
PMCID:
PMC7854524
AbstractArticlePDF–5.7M
19.
Phosphorylation of eIF2α Promotes Schwann Cell Differentiation and Myelination in CMT1B Mice with Activated UPR
Cristina Scapin, Cinzia Ferri, Emanuela Pettinato, Francesca Bianchi, Ubaldo Del Carro, M. Laura Feltri, Randal J. Kaufman, Lawrence Wrabetz, Maurizio D'Antonio
J Neurosci. 2020 Oct 14; 40(42): 8174–8187. doi: 10.1523/JNEUROSCI.0957-20.2020
PMCID:
PMC7574653
AbstractArticlePDF–4.7M
20.
Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation
Kim Schneider, Geoffrey Michael Nelson, Joseph Luke Watson, Jörg Morf, Maximillian Dalglish, Laura Martina Luh, Annika Weber, Anne Bertolotti
Cell Rep. 2020 Sep 15; 32(11): 108154. Published online 2020 Sep 15. doi: 10.1016/j.celrep.2020.108154
PMCID:
PMC7495045
AbstractArticle

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