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Select item 112275891.

Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a

Ting Zhao, Yan Hong, Bowen Yan, Suming Huang, Guo-li Ming, Hongjun Song

Nat Commun. 2024; 15: 5674. Published online 2024 Jul 6. doi: 10.1038/s41467-024-50010-y

PMCID:: PMC11227589

Abstract Article PDF–3.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102561733.

Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders

Kisho Obi-Nagata, Norimitsu Suzuki, Ryuhei Miyake, Matthew L. MacDonald, Kenneth N. Fish, Katsuya Ozawa, Kenichiro Nagahama, Tsukasa Okimura, Shoji Tanaka, Masanobu Kano, Yugo Fukazawa, Robert A. Sweet, Akiko Hayashi-Takagi

Sci Adv. 2023 Jun; 9(23): eade5973. Published online 2023 Jun 9. doi: 10.1126/sciadv.ade5973

PMCID:: PMC10256173

Abstract Article PDF–1.8M

Select item 102037104.

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos

Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng

Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245

PMCID:: PMC10203710

Abstract Article PDF–4.6M

Select item 94766305.

Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function

Nicholas E Clifton, Matthew L Bosworth, Niels Haan, Elliott Rees, Peter A Holmans, Lawrence S Wilkinson, Anthony R Isles, Mark O Collins, Jeremy Hall

Hum Mol Genet. 2022 Sep 15; 31(18): 3095–3106. Published online 2022 May 9. doi: 10.1093/hmg/ddac105

PMCID:: PMC9476630

Abstract Article PDF–1018K

Select item 91846436.

An in vitro model of neuronal ensembles

M. Angeles Rabadan, Estanislao Daniel De La Cruz, Sneha B. Rao, Yannan Chen, Cheng Gong, Gregg Crabtree, Bin Xu, Sander Markx, Joseph A. Gogos, Rafael Yuste, Raju Tomer

Nat Commun. 2022; 13: 3340. Published online 2022 Jun 9. doi: 10.1038/s41467-022-31073-1

PMCID:: PMC9184643

Abstract Article PDF–3.9M

Select item 91716097.

A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells

Bercin K. Cenik, Christie C. Sze, Caila A. Ryan, Siddhartha Das, Kaixiang Cao, Delphine Douillet, Emily J. Rendleman, Didi Zha, Nabiha Haleema Khan, Elizabeth Bartom, Ali Shilatifard

Proc Natl Acad Sci U S A. 2022 May 10; 119(19): e2118385119. Published online 2022 May 2. doi: 10.1073/pnas.2118385119

PMCID:: PMC9171609

Abstract Article PDF–2.6M

Select item 88967938.

Cell type–specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis

Renchao Chen, Yiqiong Liu, Mohamed N. Djekidel, Wenqiang Chen, Aritra Bhattacherjee, Zhiyuan Chen, Ed Scolnick, Yi Zhang

Sci Adv. 2022 Mar; 8(9): eabm1077. Published online 2022 Mar 4. doi: 10.1126/sciadv.abm1077

PMCID:: PMC8896793

Abstract Article PDF–2.2M

Select item 83338719.

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice

Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao

Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931

PMCID:: PMC8333871

Abstract Article PDF–1.4M

Select item 810749810.

Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1

Xiaoyue Deng, Toshiro Iwagawa, Masaya Fukushima, Yutaka Suzuki, Sumiko Watanabe

Invest Ophthalmol Vis Sci. 2021 May; 62(6): 1. Published online 2021 May 3. doi: 10.1167/iovs.62.6.1

PMCID:: PMC8107498

Abstract Article PDF–10M

Select item 787383711.

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

Franziska Greulich, Michael Wierer, Aikaterini Mechtidou, Omar Gonzalez-Garcia, N. Henriette Uhlenhaut

Cell Rep. 2021 Feb 9; 34(6): 108742. Published online 2021 Feb 9. doi: 10.1016/j.celrep.2021.108742

PMCID:: PMC7873837

Abstract Article

Select item 701034812.

Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice

Jun Mukai, Enrico Cannavò, Gregg W. Crabtree, Ziyi Sun, Anastasia Diamantopoulou, Pratibha Thakur, Chia-Yuan Chang, Yifei Cai, Stavros Lomvardas, Atsushi Takata, Bin Xu, Joseph A. Gogos

Neuron. Author manuscript; available in PMC 2020 Nov 6.

Published in final edited form as: Neuron. 2019 Nov 6; 104(3): 471–487.e12. Published online 2019 Oct 9. doi: 10.1016/j.neuron.2019.09.014

PMCID:: PMC7010348

Abstract Article PDF–2.0M

Select item 686415413.

De Novo and Inherited SETD1A Variants in Early-onset Epilepsy

Xiuya Yu, Lin Yang, Jin Li, Wanxing Li, Dongzhi Li, Ran Wang, Kai Wu, Wenhao Chen, Yi Zhang, Zilong Qiu, Wenhao Zhou

Neurosci Bull. 2019 Dec; 35(6): 1045–1057. Published online 2019 Jun 13. doi: 10.1007/s12264-019-00400-w

PMCID:: PMC6864154

Abstract Article PDF–2.2M

Select item 645951014.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 605244515.

A non-catalytic function of SETD1A regulates Cyclin-K and the DNA damage response

Takayuki Hoshii, Paolo Cifani, Zhaohui Feng, Chun-Hao Huang, Richard Koche, Chun-Wei Chen, Christopher D. Delaney, Scott W. Lowe, Alex Kentsis, Scott A. Armstrong

Cell. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Cell. 2018 Feb 22; 172(5): 1007–1021.e17. doi: 10.1016/j.cell.2018.01.032

PMCID:: PMC6052445

Abstract Article PDF–2.3M

Select item 603006416.

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Kun-Yong Kim, Yoshiaki Tanaka, Juan Su, Bilal Cakir, Yangfei Xiang, Benjamin Patterson, Junjun Ding, Yong-Wook Jung, Ji-Hyun Kim, Eriona Hysolli, Haelim Lee, Rana Dajani, Jonghwan Kim, Mei Zhong, Jeong-Heon Lee, David Skalnik, Jeong Mook Lim, Gareth J. Sullivan, Jianlong Wang, In-Hyun Park

Nat Commun. 2018; 9: 2583. Published online 2018 Jul 3. doi: 10.1038/s41467-018-04818-0

PMCID:: PMC6030064

Abstract Article PDF–3.3M

Select item 566667217.

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation

Christie C. Sze, Kaixiang Cao, Clayton K. Collings, Stacy A. Marshall, Emily J. Rendleman, Patrick A. Ozark, Fei Xavier Chen, Marc A. Morgan, Lu Wang, Ali Shilatifard

Genes Dev. 2017 Sep 1; 31(17): 1732–1737. doi: 10.1101/gad.303768.117

PMCID:: PMC5666672

Abstract Article PDF–4.7M

Select item 543589118.

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

Kaixiang Cao, Clayton K. Collings, Stacy A. Marshall, Marc A. Morgan, Emily J. Rendleman, Lu Wang, Christie C. Sze, Tianjiao Sun, Elizabeth T. Bartom, Ali Shilatifard

Genes Dev. 2017 Apr 15; 31(8): 787–801. doi: 10.1101/gad.294744.116

PMCID:: PMC5435891

Abstract Article PDF–603K

Select item 529782319.

MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

Ya-Ling Yang, Feng-Sheng Wang, Sung-Chou Li, Mao-Meng Tiao, Ying-Hsien Huang

Int J Mol Sci. 2017 Jan; 18(1): 192. Published online 2017 Jan 18. doi: 10.3390/ijms18010192

PMCID:: PMC5297823

Abstract Article PDF–7.4M

Select item 500972420.

Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation

Ying Li, Vincent P. Schulz, Changwang Deng, Guangyao Li, Yong Shen, Betsabeh K. Tusi, Gina Ma, Jared Stees, Yi Qiu, Laurie A. Steiner, Lei Zhou, Keji Zhao, Jörg Bungert, Patrick G. Gallagher, Suming Huang

Nucleic Acids Res. 2016 Sep 6; 44(15): 7173–7188. Published online 2016 May 3. doi: 10.1093/nar/gkw327

PMCID:: PMC5009724

Abstract Article PDF–6.6M

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