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Select item 112522701.

ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis

Jiahui Du, Yili Liu, Jinrui Sun, Enhui Yao, Jingyi Xu, Xiaolin Wu, Ling Xu, Mingliang Zhou, Guangzheng Yang, Xinquan Jiang

Nat Commun. 2024; 15: 5994. Published online 2024 Jul 17. doi: 10.1038/s41467-024-50225-z

PMCID:: PMC11252270

Abstract Article PDF–9.9M

Select item 109421082.

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations

Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera

Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435

PMCID:: PMC10942108

Abstract Article PDF–9.8M

Select item 106326773.

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis

Vikas Madan, Pavithra Shyamsunder, Pushkar Dakle, Teoh Weoi Woon, Lin Han, Zeya Cao, Hazimah Binte Mohd Nordin, Shi Jizhong, Yu Shuizhou, Md Zakir Hossain, H. Phillip Koeffler

Blood Adv. 2023 Nov 14; 7(21): 6553–6566. Published online 2023 Aug 25. doi: 10.1182/bloodadvances.2023009946

PMCID:: PMC10632677

Abstract Article PDF–1.1M

Select item 104042864.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 102815645.

Canonical BAF complex activity shapes the enhancer landscape that licenses CD8⁺ T cell effector and memory fates

Bryan McDonald, Brent Y. Chick, Nasiha S. Ahmed, Mannix Burns, Shixin Ma, Eduardo Casillas, Dan Chen, Thomas H. Mann, Carolyn O’ Connor, Nasun Hah, Diana C. Hargreaves, Susan M. Kaech

Immunity. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Immunity. 2023 Jun 13; 56(6): 1303–1319.e5. doi: 10.1016/j.immuni.2023.05.005

PMCID:: PMC10281564

Abstract Article PDF–3.0M

Select item 102767706.

Arid1a regulates bladder urothelium formation and maintenance

Chunming Guo, Yingsheng Zhang, Ruirong Tan, Zonghao Tang, Christa M. Lam, Xing Ye, Zhong Wang, Xue Li

Dev Biol. Author manuscript; available in PMC 2023 Jun 18.

Published in final edited form as: Dev Biol. 2022 May; 485: 61–69. Published online 2022 Mar 10. doi: 10.1016/j.ydbio.2022.02.008

PMCID:: PMC10276770

Abstract Article PDF–2.6M

Select item 102127167.

Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain

Yuanyuan Wang, Libo Su, Wenwen Wang, Jinyue Zhao, Yanyan Wang, Sihan Li, Yan Liu, Renjie Chai, Xin Li, Zhaoqian Teng, Changmei Liu, Baoyang Hu, Fen Ji, Jianwei Jiao

Cell Prolif. 2023 May; 56(5): e13447. Published online 2023 Mar 13. doi: 10.1111/cpr.13447

PMCID:: PMC10212716

Abstract Article PDF–4.7M

Select item 100858648.

Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

Wei Zhou, Heng Liu, Zhe Yuan, Joseph Zundell, Martina Towers, Jianhuang Lin, Simona Lombardi, Hao Nie, Brennah Murphy, Tyler Yang, Chen Wang, Liping Liao, Aaron R. Goldman, Toshitha Kannan, Andrew V. Kossenkov, Ronny Drapkin, Luis J. Montaner, Daniel T. Claiborne, Nan Zhang, Shuai Wu, Rugang Zhang

Cancer Cell. Author manuscript; available in PMC 2024 Apr 10.

Published in final edited form as: Cancer Cell. 2023 Apr 10; 41(4): 740–756.e10. Published online 2023 Mar 23. doi: 10.1016/j.ccell.2023.03.002

PMCID:: PMC10085864

Abstract Article PDF–3.6M

Select item 98409369.

ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance

Tzu-Lei Kuo, Kuang-Hung Cheng, Li-Tzong Chen, Wen-Chun Hung

iScience. 2023 Jan 20; 26(1): 105881. Published online 2022 Dec 27. doi: 10.1016/j.isci.2022.105881

PMCID:: PMC9840936

Abstract Article PDF–4.2M

Select item 980859910.

Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

Bing Guo, Scott C. Friedland, William Alexander, Jacquelyn A. Myers, Wenjia Wang, Michael R. O’Dell, Michael Getman, Christa L. Whitney-Miller, Diana Agostini-Vulaj, Aaron R. Huber, Stephano S. Mello, Paula M. Vertino, Hartmut K. Land, Laurie A. Steiner, Aram F. Hezel

Cell Rep. Author manuscript; available in PMC 2023 Jan 3.

Published in final edited form as: Cell Rep. 2022 Aug 30; 40(9): 111253. doi: 10.1016/j.celrep.2022.111253

PMCID:: PMC9808599

Abstract Article PDF–3.3M

Select item 963715811.

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis

Pengfei Guo, Nam Hoang, Joseph Sanchez, Elaine H. Zhang, Keshari Rajawasam, Kristiana Trinidad, Hong Sun, Hui Zhang

Nat Commun. 2022; 13: 6696. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34348-9

PMCID:: PMC9637158

Abstract Article PDF–3.3M

Select item 962824912.

Abnormal microglial polarization induced by Arid1a deletion leads to neuronal differentiation deficits

Maolei Gong, Ruoxi Shi, Yijun Liu, Jinpeng Ke, Xiao Liu, Hong‐Zhen Du, Chang‐Mei Liu

Cell Prolif. 2022 Nov; 55(11): e13314. Published online 2022 Jul 19. doi: 10.1111/cpr.13314

PMCID:: PMC9628249

Abstract Article PDF–7.6M

Select item 962303613.

cBAF complex components and MYC cooperate early in CD8⁺ T cell fate

Ao Guo, Hongling Huang, Zhexin Zhu, Mark J. Chen, Hao Shi, Sujing Yuan, Piyush Sharma, Jon P. Connelly, Swantje Liedmann, Yogesh Dhungana, Zhenrui Li, Dalia Haydar, Mao Yang, Helen Beere, Jason T Yustein, Christopher DeRenzo, Shondra M. Pruett-Miller, Jeremy Chase Crawford, Giedre Krenciute, Charles W.M. Roberts, Hongbo Chi, Douglas R. Green

Nature. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Nature. 2022 Jul; 607(7917): 135–141. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04849-0

PMCID:: PMC9623036

Abstract Article PDF–6.1M

Select item 945110314.

GLS1 is a Protective Factor in Patients with Ovarian Clear Cell Carcinoma and its Expression Does Not Correlate with ARID1A-mutated Tumors

Valentino Clemente, Asumi Hoshino, Mihir Shetty, Andrew Nelson, Britt K. Erickson, Ruth Baker, Nathan Rubin, Mahmoud Khalifa, S. John Weroha, Emil Lou, Martina Bazzaro

Cancer Res Commun. 2022 Aug; 2(8): 784–794. Published online 2022 Aug 10. doi: 10.1158/2767-9764.CRC-22-0122

PMCID:: PMC9451103

Abstract Article PDF–10M

Select item 918130115.

Endometrial Epithelial ARID1A Is Required for Uterine Immune Homeostasis during Early Pregnancy

Ryan M. Marquardt, Soo Hyun Ahn, Jake J. Reske, Ronald L. Chandler, Margaret G. Petroff, Tae Hoon Kim, Jae-Wook Jeong

Int J Mol Sci. 2022 Jun; 23(11): 6067. Published online 2022 May 28. doi: 10.3390/ijms23116067

PMCID:: PMC9181301

Abstract Article PDF–3.5M

Select item 916876216.

ARID1A‐deficient cells require HDAC6 for progression of endometrial carcinoma

Cristina Megino‐Luque, Pol Sisó, Natalia Mota‐Martorell, Raúl Navaridas, Inés de la Rosa, Izaskun Urdanibia, Manel Albertí‐Valls, Maria Santacana, Miquel Pinyol, Núria Bonifaci, Anna Macià, David Llobet‐Navas, Sònia Gatius, Xavier Matias‐Guiu, Núria Eritja

Mol Oncol. 2022 Jun; 16(11): 2235–2259. Published online 2022 Mar 2. doi: 10.1002/1878-0261.13193

PMCID:: PMC9168762

Abstract Article PDF–13M

Select item 872335317.

Targeting the IRE1α/XBP1 endoplasmic reticulum stress response pathway in ARID1A-mutant ovarian cancers

Joseph A. Zundell, Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov, Qin Liu, Joel Cassel, Chih-Chi Andrew Hu, Shuai Wu, Rugang Zhang

Cancer Res. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Cancer Res. 2021 Oct 15; 81(20): 5325–5335. Published online 2021 Sep 21. doi: 10.1158/0008-5472.CAN-21-1545

PMCID:: PMC8723353

Abstract Article PDF–2.0M

Select item 857870418.

Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

Seraina Blümli, Nicola Wiechens, Meng-Ying Wu, Vijender Singh, Marek Gierlinski, Gabriele Schweikert, Nick Gilbert, Catherine Naughton, Ramasubramanian Sundaramoorthy, Joby Varghese, Robert Gourlay, Renata Soares, David Clark, Tom Owen-Hughes

Cell Rep. 2021 Nov 2; 37(5): 109943. Published online 2021 Nov 2. doi: 10.1016/j.celrep.2021.109943

PMCID:: PMC8578704

Abstract Article

Select item 856060619.

Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development

Xiao Liu, Shang‐Kun Dai, Pei‐Pei Liu, Chang‐Mei Liu

Cell Prolif. 2021 Nov; 54(11): e13124. Published online 2021 Sep 25. doi: 10.1111/cpr.13124

PMCID:: PMC8560606

Abstract Article PDF–2.6M

Select item 854203820.

ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis

Xue-Ying Shang, Yi Shi, Dan-Dan He, Lan Wang, Qing Luo, Chuan-Huai Deng, Yu-Lan Qu, Na Wang, Ze-Guang Han

Cell Death Dis. 2021 Nov; 12(11): 990. Published online 2021 Oct 23. doi: 10.1038/s41419-021-04291-6

PMCID:: PMC8542038

Abstract Article PDF–5.1M

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