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Select item 110834431.

Divergent and Compensatory Effects of BMP2 and BMP4 on the VSMC Phenotype and BMP4’s Role in Thoracic Aortic Aneurysm Development

Daniel Klessinger, Argen Mamazhakypov, Sophie Glaeser, Ramona Emig, Remi Peyronnet, Lena Meier, Kora Proelss, Katia Marenne, Christian Smolka, Sebastian Grundmann, Franziska Pankratz, Philipp R. Esser, Martin Moser, Qian Zhou, Jennifer S. Esser

Cells. 2024 May; 13(9): 735. Published online 2024 Apr 24. doi: 10.3390/cells13090735

PMCID:: PMC11083443

Abstract Article PDF–6.2M

Select item 110787592.

Control of neuronal excitation–inhibition balance by BMP–SMAD1 signalling

Zeynep Okur, Nadia Schlauri, Vassilis Bitsikas, Myrto Panopoulou, Raul Ortiz, Michaela Schwaiger, Kajari Karmakar, Dietmar Schreiner, Peter Scheiffele

Nature. 2024; 629(8011): 402–409. Published online 2024 Apr 17. doi: 10.1038/s41586-024-07317-z

PMCID:: PMC11078759

Abstract Article PDF–13M

Select item 109954783.

Synthetic biology‐based bacterial extracellular vesicles displaying BMP‐2 and CXCR4 to ameliorate osteoporosis

Han Liu, Peiran Song, Hao Zhang, Fengjin Zhou, Ning Ji, Mingkai Wang, Guangyin Zhou, Ruina Han, Xinru Liu, Weizong Weng, Haoqi Tan, Sicheng Wang, Lei Zheng, Yingying Jing, Jiacan Su

J Extracell Vesicles. 2024 Apr; 13(4): e12429. Published online 2024 Apr 4. doi: 10.1002/jev2.12429

PMCID:: PMC10995478

Abstract Article PDF–3.0M

Select item 106629724.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 105473005.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 103229166.

Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

Adriana Ibarra Urizar, Michala Prause, Lars Roed Ingerslev, Matthew Wortham, Yinghui Sui, Maike Sander, Kristine Williams, Romain Barrès, Martin R. Larsen, Gitte Lund Christensen, Nils Billestrup

Cell Death Dis. 2023 Jul; 14(7): 399. Published online 2023 Jul 5. doi: 10.1038/s41419-023-05906-w

PMCID:: PMC10322916

Abstract Article PDF–2.9M

Select item 103109297.

β-Catenin regulates endocardial cushion growth by suppressing p21

Huahua Liu, Pengfei Lu, Shan He, Yuru Luo, Yuan Fang, Sonia Benkaci, Bingruo Wu, Yidong Wang, Bin Zhou

Life Sci Alliance. 2023 Sep; 6(9): e202302163. Published online 2023 Jun 29. doi: 10.26508/lsa.202302163

PMCID:: PMC10310929

Abstract Article PDF–4.2M

Select item 102855498.

Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

Vijay K. Sirohi, Theresa I. Medrano, Athilakshmi Kannan, Indrani C. Bagchi, Paul S. Cooke

iScience. 2023 Jul 21; 26(7): 107028. Published online 2023 Jun 8. doi: 10.1016/j.isci.2023.107028

PMCID:: PMC10285549

Abstract Article PDF–5.7M

Select item 102817519.

SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2

Andrés Hernández-García, Katherine E Pendleton, Sangbae Kim, Yumei Li, Bum J Kim, Hitisha P Zaveri, Valerie K Jordan, Aliska M Berry, M Cecilia Ljungberg, Rui Chen, Rainer B Lanz, Daryl A Scott

Hum Mol Genet. 2023 Jul 1; 32(13): 2152–2161. Published online 2023 Mar 31. doi: 10.1093/hmg/ddad050

PMCID:: PMC10281751

Abstract Article PDF–1.6M

Select item 1025951410.

Dysfunction of programmed embryo senescence is linked to genetic developmental defects

Cristina de Lope, Rebeca García-Lucena, Marta Magariños, Yolanda León, Nuria Casa-Rodríguez, Nuria Contreras, Carmen Escudero-Iriarte, Isabel Varela-Nieto, Pascal Maire, Ignacio Palmero

Development. 2023 May 1; 150(9): dev200903. Published online 2023 May 3. doi: 10.1242/dev.200903

PMCID:: PMC10259514

Abstract Article

Select item 1017971811.

BMP-2 Genome-Edited Human MSCs Protect against Cartilage Degeneration via Suppression of IL-34 in Collagen-Induced Arthritis

Dong-Sik Chae, Seongho Han, Min-Kyung Lee, Sung-Whan Kim

Int J Mol Sci. 2023 May; 24(9): 8223. Published online 2023 May 4. doi: 10.3390/ijms24098223

PMCID:: PMC10179718

Abstract Article PDF–2.9M

Select item 1007300912.

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse

Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L. Galea, Nicholas D. E. Greene, Andrew J. Copp

Dis Model Mech. 2023 Mar 1; 16(3): dmm049858. Published online 2023 Mar 14. doi: 10.1242/dmm.049858

PMCID:: PMC10073009

Abstract Article

Select item 1006076413.

Inhibition of BMP2 and BMP4 Represses Barrett’s Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models

Ana C.P. Correia, Danielle Straub, Matthew Read, Sanne J.M. Hoefnagel, Salvador Romero-Pinedo, Ana C. Abadía-Molina, Nicholas J. Clemons, Kenneth Wang, Silvia Calpe, Wayne Phillips, Kausilia K. Krishnadath

Cell Mol Gastroenterol Hepatol. 2023; 15(5): 1199–1217. Published online 2023 Jan 25. doi: 10.1016/j.jcmgh.2023.01.003

PMCID:: PMC10060764

Abstract Article PDF–11M

Select item 983364514.

Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4

Gaetano D’Amato, Ragini Phansalkar, Jeffrey A. Naftaly, Xiaochen Fan, Zhainib A. Amir, Pamela E. Rios Coronado, Dale O. Cowley, Kelsey E. Quinn, Bikram Sharma, Kathleen M. Caron, Alessandra Vigilante, Kristy Red-Horse

Dev Cell. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: Dev Cell. 2022 Nov 21; 57(22): 2517–2532.e6. Published online 2022 Nov 7. doi: 10.1016/j.devcel.2022.10.007

PMCID:: PMC9833645

Abstract Article PDF–3.0M

Select item 976767515.

Bone morphogenetic protein 2- and estradiol-17β-induced changes in ovarian transcriptome during primordial follicle formation

Prabuddha Chakraborty, Rebecca L Anderson, Shyamal K Roy

Biol Reprod. 2022 Sep; 107(3): 800–812. Published online 2022 May 25. doi: 10.1093/biolre/ioac111

PMCID:: PMC9767675

Abstract Article PDF–2.7M

Select item 972857816.

BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation

Bing Li, Wenbin An, Hua Wang, Timour Baslan, Shoron Mowla, Aishwarya Krishnan, Wenbin Xiao, Richard P. Koche, Ying Liu, Sheng F. Cai, Zhijian Xiao, Andriy Derkach, Ilaria Iacobucci, Charles G. Mullighan, Kristian Helin, Scott W. Lowe, Ross L. Levine, Raajit K. Rampal

Blood. 2022 Jun 23; 139(25): 3630–3646. Published online 2022 Apr 18. doi: 10.1182/blood.2021014465

PMCID:: PMC9728578

Abstract Article

Select item 968184317.

Angiopoietin-like 2 is essential to aortic valve development in mice

Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani, Maya Mamarbachi, Frédéric Lesage, Samuel Mathieu, Jean-Claude Tardif, Patrick Mathieu, Marie Kmita, Éric Thorin

Commun Biol. 2022; 5: 1277. Published online 2022 Nov 21. doi: 10.1038/s42003-022-04243-6

PMCID:: PMC9681843

Abstract Article PDF–13M

Select item 938289518.

Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2

Shuyi Mai, Xiaoxuan Zhu, Esther Yi Ching Wan, Shengyu Wu, Jesslyn Nagalin Yonathan, Jun Wang, Ying Li, Jessica Yuen Wuen Ma, Bing Zuo, Dennis Yan-yin Tse, Pui-Chi Lo, Xin Wang, Kui Ming Chan, David M. Wu, Wenjun Xiong

Development. 2022 Jul 15; 149(14): dev200633. Published online 2022 Jul 14. doi: 10.1242/dev.200633

PMCID:: PMC9382895

Abstract Article

Select item 910554419.

Loss of Smad4 in the Scleraxis Cell Lineage Results in Postnatal Joint Contracture

Saundra Schlesinger, Seongkyung Seo, Brian Pryce, Sara F. Tufa, Douglas R. Keene, Alice H. Huang, Ronen Schweitzer

Dev Biol. Author manuscript; available in PMC 2022 May 13.

Published in final edited form as: Dev Biol. 2021 Feb; 470: 108–120. Published online 2020 Nov 25. doi: 10.1016/j.ydbio.2020.11.006

PMCID:: PMC9105544

Abstract Article PDF–2.4M

Select item 904911920.

BMP/SMAD1/5 Signaling in the Endometrial Epithelium Is Essential for Receptivity and Early Pregnancy

Suni Tang, Dominique I Cope, Yasmin M Vasquez, Diana Monsivais

Endocrinology. 2022 May; 163(5): bqac043. Published online 2022 Apr 6. doi: 10.1210/endocr/bqac043

PMCID:: PMC9049119

Abstract Article

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