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Items: 1 to 20 of 94

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis
Shuai Zhang, Yu Sun, Qi Xiao, Mengying Niu, Xudong Pan, Xiaoyan Zhu
Mol Neurobiol. 2023; 60(5): 2572–2586. Published online 2023 Jan 23. doi: 10.1007/s12035-023-03214-0
PMCID:
PMC10039837
AbstractArticlePDF–2.7M
3.
Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism
Hyuk Nam Kwon, Kristen Kurtzeborn, Vladislav Iaroshenko, Xing Jin, Abigail Loh, Nathalie Escande-Beillard, Bruno Reversade, Sunghyouk Park, Satu Kuure
Development. 2022 Oct 1; 149(19): dev200986. Published online 2022 Oct 3. doi: 10.1242/dev.200986
PMCID:
PMC9641663
AbstractArticle
4.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
5.
Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway
Jung-Min Kim, Yeon-Suk Yang, Jaehyoung Hong, Sachin Chaugule, Hyonho Chun, Marjolein CH van der Meulen, Ren Xu, Matthew B Greenblatt, Jae-hyuck Shim
eLife. 2022; 11: e78069. Published online 2022 Aug 17. doi: 10.7554/eLife.78069
PMCID:
PMC9417416
AbstractArticlePDF–5.4M
6.
Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney
Kristen Kurtzeborn, Hyuk Nam Kwon, Vladislav Iaroshenko, Imrul Faisal, Martin Ambrož, Xing Jin, Talha Qureshi, Jussi Kupari, Anneliis Ihermann-Hella, Juho Väänänen, Henna Tyynismaa, Iva Boušová, Sunghyouk Park, Satu Kuure
BMC Biol. 2022; 20: 112. Published online 2022 May 13. doi: 10.1186/s12915-022-01309-z
PMCID:
PMC9102746
AbstractArticlePDF–2.6M
7.
Phase transition specified by a binary code patterns the vertebrate eye cup
Revathi Balasubramanian, Xuanyu Min, Peter M. J. Quinn, Quentin Lo Giudice, Chenqi Tao, Karina Polanco, Neoklis Makrides, John Peregrin, Michael Bouaziz, Yingyu Mao, Qian Wang, Bruna L. da Costa, Diego Buenaventura, Fen Wang, Liang Ma, Stephen H. Tsang, Pierre J. Fabre, Xin Zhang
Sci Adv. 2021 Nov; 7(46): eabj9846. Published online 2021 Nov 10. doi: 10.1126/sciadv.abj9846
PMCID:
PMC8580326
AbstractArticlePDF–3.8M
8.
Mek1 and Mek2 Functional Redundancy in Erythropoiesis
Laurent Beuret, Simon-Pierre Fortier-Beaulieu, Vincent Rondeau, Sophie Roy, Nicolas Houde, Karl Balabanian, Marion Espéli, Jean Charron
Front Cell Dev Biol. 2021; 9: 639022. Published online 2021 Jul 27. doi: 10.3389/fcell.2021.639022
PMCID:
PMC8353236
AbstractArticlePDF–4.3M
9.
VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9 dependent pathway
Ming Jiang, Yinshan Fang, Yu Li, Huachao Huang, Zichen Wei, Xia Gao, Hoon-Ki Sung, Jim Hu, Li Qiang, Jian Ruan, Qixuan Chen, Dianhua Jiang, Jeffrey A. Whitsett, Xingbin Ai, Jianwen Que
Dev Cell. Author manuscript; available in PMC 2022 Jun 7.
Published in final edited form as: Dev Cell. 2021 Jun 7; 56(11): 1646–1660.e5. Published online 2021 May 18. doi: 10.1016/j.devcel.2021.04.027
PMCID:
PMC8187331
AbstractArticlePDF–3.5M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer
Sanja Pajovic, Robert Siddaway, Taylor Bridge, Javal Sheth, Patricia Rakopoulos, Byungjin Kim, Scott Ryall, Sameer Agnihotri, Lauren Phillips, Man Yu, Christopher Li, Scott Milos, Palak Patel, Dilakshan Srikanthan, Annie Huang, Cynthia Hawkins
Nat Commun. 2020; 11: 6216. Published online 2020 Dec 4. doi: 10.1038/s41467-020-19972-7
PMCID:
PMC7718276
AbstractArticlePDF–2.5M
12.
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
Chiara Falcomatà, Stefanie Bärthel, Sebastian A. Widholz, Christian Schneeweis, Juan José Montero, Albulena Toska, Jonas Mir, Thorsten Kaltenbacher, Jeannine Heetmeyer, Jonathan J Swietlik, Jing-Yuan Cheng, Bianca Teodorescu, Oliver Reichert, Constantin Schmitt, Kathrin Grabichler, Andrea Coluccio, Fabio Boniolo, Christian Veltkamp, Magdalena Zukowska, Angelica Arenas Vargas, Woo Hyun Paik, Moritz Jesinghaus, Katja Steiger, Roman Maresch, Rupert Öllinger, Tim Ammon, Olga Baranov, Maria S. Robles, Julia Rechenberger, Bernhard Kuster, Felix Meissner, Maximilian Reichert, Michael Flossdorf, Roland Rad, Marc Schmidt-Supprian, Günter Schneider, Dieter Saur
Nat Cancer. Author manuscript; available in PMC 2022 Jul 31.
Published in final edited form as: Nat Cancer. 2022 Mar 1; 3(3): 318–336. Published online 2022 Jan 31. doi: 10.1038/s43018-021-00326-1
PMCID:
PMC7612546
AbstractArticlePDF–8.9M
13.
Etv transcription factors functionally diverge from their upstream FGF signaling in lens development
Ankur Garg, Abdul Hannan, Qian Wang, Neoklis Makrides, Jian Zhong, Hongge Li, Sungtae Yoon, Yingyu Mao, Xin Zhang
eLife. 2020; 9: e51915. Published online 2020 Feb 11. doi: 10.7554/eLife.51915
PMCID:
PMC7069720
AbstractArticlePDF–6.3M
14.
Molecular pathways of senescence regulate placental structure and function
Hilah Gal, Marina Lysenko, Sima Stroganov, Ezra Vadai, Sameh A Youssef, Keren Tzadikevitch‐Geffen, Ron Rotkopf, Tal Biron‐Shental, Alain de Bruin, Michal Neeman, Valery Krizhanovsky
EMBO J. 2019 Sep 16; 38(18): e100849. Published online 2019 Aug 19. doi: 10.15252/embj.2018100849
Correction in:
EMBO J. 2020 Aug 3; 39(15): e105972.
PMCID:
PMC6745498
AbstractArticlePDF–2.1M
15.
Inhibitors of the Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Pathway Clear Prion-Infected Cells from PrPSc
Elin K. Nordström, Katarina M. Luhr, Carlos Ibáñez, Krister Kristensson
J Neurosci. 2005 Sep 14; 25(37): 8451–8456. doi: 10.1523/JNEUROSCI.2349-05.2005
PMCID:
PMC6725673
AbstractArticlePDF–239K
16.
Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development
Sakiko Matsumoto, Sumiko Kiryu-Seo, Hiroshi Kiyama
J Neurosci. 2016 Apr 27; 36(17): 4744–4757. doi: 10.1523/JNEUROSCI.3811-15.2016
PMCID:
PMC6601721
AbstractArticlePDF–5.8M
17.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
18.
MEK2 negatively Regulates LPS Mediated IL-1β Production Through HIF-1α Expression
Harvinder Talwar, Mohamad Bouhamdan, Christian Bauerfeld, Jaya Talreja, Rifdat Aoidi, Nicolas Houde, Jean Charron, Lobelia Samavati
J Immunol. Author manuscript; available in PMC 2020 Mar 15.
Published in final edited form as: J Immunol. 2019 Mar 15; 202(6): 1815–1825. Published online 2019 Feb 1. doi: 10.4049/jimmunol.1801477
PMCID:
PMC6401293
AbstractArticlePDF–900K
19.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
20.
FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination
Ankur Garg, Abdul Hannan, Qian Wang, Tamica Collins, Siying Teng, Mukesh Bansal, Jian Zhong, Keli Xu, Xin Zhang
PLoS Genet. 2018 Sep; 14(9): e1007660. Published online 2018 Sep 6. doi: 10.1371/journal.pgen.1007660
PMCID:
PMC6143274
AbstractArticlePDF–2.7M

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