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Select item 113736211.

Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system

Yueheng Wu, Shaoxian Chen, Guiping Huang, Lu Zhang, Liying Zhong, Yi Feng, Pengju Wen, Juli Liu

Theranostics. 2024; 14(12): 4894–4915. Published online 2024 Aug 12. doi: 10.7150/thno.92060

PMCID:: PMC11373621

Abstract Article PDF–12M

Select item 113351882.

SGK3 deficiency in macrophages suppresses angiotensin II–induced cardiac remodeling via regulating Ndufa13–mediated mitochondrial oxidative stress

Jiayu Ren, Yilin Che, Heyu Li, Haijun Gao, Yue Wang, Ying Wang, Hongtong Su, Zhihan Li, Jing Li, Peng Qu

Cell Mol Life Sci. 2024 Dec; 81(1): 359. Published online 2024 Aug 19. doi: 10.1007/s00018-024-05395-w

PMCID:: PMC11335188

Abstract Article PDF–22M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99382164.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 97683775.

Grim-19 plays a key role in mitochondrial steroidogenic acute regulatory protein stability and ligand-binding properties in Leydig cells

Hu Qu, Ke He, Zi-hao Zou, Gang Niu, Li Lu, Bing Yao, Wen-wen Zhong, De-juan Wang, Wei Li

J Biol Chem. 2022 Dec; 298(12): 102671. Published online 2022 Nov 2. doi: 10.1016/j.jbc.2022.102671

PMCID:: PMC9768377

Abstract Article PDF–5.1M

Select item 96410286.

Grim-19 deficiency promotes decidual macrophage autophagy in recurrent spontaneous abortion

Yang Yang, Haoran Liu, Yue Zhao, Chen Geng, Lan Chao, Aijun Hao

Front Endocrinol (Lausanne) 2022; 13: 1023194. Published online 2022 Oct 25. doi: 10.3389/fendo.2022.1023194

PMCID:: PMC9641028

Abstract Article PDF–8.5M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78299878.

GRIM19 Impedes Obesity by Regulating Inflammatory White Fat Browning and Promoting Th17/Treg Balance

JooYeon Jhun, Jin Seok Woo, Seung Hoon Lee, Jeong-Hee Jeong, KyungAh Jung, Wonhee Hur, Seon-Yeong Lee, Jae Yoon Ryu, Young-Mee Moon, Yoon Ju Jung, Kyo Young Song, Kiyuk Chang, Seung Kew Yoon, Sung-Hwan Park, Mi-La Cho

Cells. 2021 Jan; 10(1): 162. Published online 2021 Jan 15. doi: 10.3390/cells10010162

PMCID:: PMC7829987

Abstract Article PDF–3.9M

Select item 62980409.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 605672010.

Assembly of mammalian oxidative phosphorylation complexes I–V and supercomplexes

Alba Signes, Erika Fernandez-Vizarra

Essays Biochem. 2018 Jul 20; 62(3): 255–270. Published online 2018 Jul 20. doi: 10.1042/EBC20170098

PMCID:: PMC6056720

Abstract Article PDF–1.5M

Select item 579902311.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 579538812.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

Select item 569253213.

Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3

Hengxun Hu, Jinliang Nan, Yong Sun, Dan Zhu, Changchen Xiao, Yaping Wang, Lianlian Zhu, Yue Wu, Jing Zhao, Rongrong Wu, Jinghai Chen, Hong Yu, Xinyang Hu, Wei Zhu, Jian’an Wang

Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11908–11913. Published online 2017 Oct 20. doi: 10.1073/pnas.1704723114

PMCID:: PMC5692532

Abstract Article PDF–1.4M

Select item 538122614.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 532103215.

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

Devin K. Schweppe, Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Shane E. Kruse, Rudy Stuppard, David J. Marcinek, Gerald S. Shadel, Rong Tian, James E. Bruce

Proc Natl Acad Sci U S A. 2017 Feb 14; 114(7): 1732–1737. Published online 2017 Jan 27. doi: 10.1073/pnas.1617220114

PMCID:: PMC5321032

Abstract Article PDF–1.1M

Select item 493893316.

GRIM19 ameliorates acute graft-versus-host disease (GVHD) by modulating Th17 and Treg cell balance through down-regulation of STAT3 and NF-AT activation

Min-Jung Park, Seung Hoon Lee, Sung-Hee Lee, Eun-Kyung Kim, Eun Jung Lee, Young-Mee Moon, Mi- La Cho

J Transl Med. 2016; 14: 206. Published online 2016 Jul 8. doi: 10.1186/s12967-016-0963-0

PMCID:: PMC4938933

Abstract Article PDF–8.5M

Select item 436324417.

Downregulation of gene expression and activity of GRIM-19 affects mouse oocyte viability, maturation, embryo development and implantation

Lan Chao, Xiao Wang, Yang Yang, Wenjuan Cui, Jing Xu, Honglei Chen, Aijun Hao, Xiaohui Deng

J Assist Reprod Genet. 2015 Mar; 32(3): 461–470. Published online 2015 Jan 6. doi: 10.1007/s10815-014-0413-y

PMCID:: PMC4363244

Abstract Article PDF–2.9M

Select item 407349418.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 383146819.

Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice

Sudhakar Kalakonda, Shreeram C. Nallar, Sausan Jaber, Susan K. Keay, Ellen Rorke, Raghava Munivenkatappa, Daniel J. Lindner, Gary M. Fiskum, Dhananjaya V. Kalvakolanu

Proc Natl Acad Sci U S A. 2013 Nov 5; 110(45): E4213–E4222. Published online 2013 Oct 21. doi: 10.1073/pnas.1303760110

PMCID:: PMC3831468

Abstract Article PDF–1.5M

Select item 359783020.

Tumor-derived Mutations in the Gene Associated with Retinoid Interferon-induced Mortality (GRIM-19) Disrupt Its Anti-signal Transducer and Activator of Transcription 3 (STAT3) Activity and Promote Oncogenesis

Shreeram C. Nallar, Sudhakar Kalakonda, Daniel J. Lindner, Robert R. Lorenz, Eric Lamarre, Xiao Weihua, Dhananjaya V. Kalvakolanu

J Biol Chem. 2013 Mar 15; 288(11): 7930–7941. Published online 2013 Feb 5. doi: 10.1074/jbc.M112.440610

PMCID:: PMC3597830

Abstract Article PDF–2.0M

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