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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine
Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova
Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452
PMCID:
PMC10253002
AbstractArticlePDF–2.4M
3.
Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl
Mol Metab. 2019 Nov; 29: 24–39. Published online 2019 Aug 13. doi: 10.1016/j.molmet.2019.08.007
PMCID:
PMC6728766
AbstractArticlePDF–3.3M
4.
Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction
Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II
Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076
PMCID:
PMC5467389
AbstractArticlePDF–3.2M
5.
Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
Angela J Churchill, Giselle Dominguez Gutiérrez, Ruth A Singer, David S Lorberbaum, Kevin A Fischer, Lori Sussel
eLife. 2017; 6: e20010. Published online 2017 Jan 10. doi: 10.7554/eLife.20010
PMCID:
PMC5224921
AbstractArticlePDF–1.9M
6.
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity
Jose Luis Muñoz-Bravo, Alvaro Flores-Martínez, Griselda Herrero-Martin, Sapna Puri, Makoto Mark Taketo, Anabel Rojas, Matthias Hebrok, David A. Cano
PLoS One. 2016; 11(10): e0164714. Published online 2016 Oct 13. doi: 10.1371/journal.pone.0164714
PMCID:
PMC5063371
AbstractArticlePDF–5.0M
7.
β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development
Ahmed M. Abdellatif, Hisashi Oishi, Takahiro Itagaki, Yunshin Jung, Hossam H. Shawki, Yukari Okita, Yoshikazu Hasegawa, Hiroyuki Suzuki, Salah E. El-Morsy, Mesbah A. El-Sayed, Mahmoud B. Shoaib, Fumihiro Sugiyama, Satoru Takahashi
PLoS One. 2016; 11(2): e0150010. Published online 2016 Feb 22. doi: 10.1371/journal.pone.0150010
PMCID:
PMC4763111
AbstractArticlePDF–14M
8.
Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells
Julie Piccand, Perrine Strasser, David J. Hodson, Aline Meunier, Tao Ye, Céline Keime, Marie-Christine Birling, Guy A. Rutter, Gérard Gradwohl
Cell Rep. 2014 Dec 24; 9(6): 2219–2232. Published online 2014 Dec 11. doi: 10.1016/j.celrep.2014.11.033
PMCID:
PMC4542305
AbstractArticlePDF–4.1M
9.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
10.
Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man
Sarah E. Flanagan, Elisa De Franco, Hana Lango Allen, Michele Zerah, Majedah M. Abdul-Rasoul, Julie A. Edge, Helen Stewart, Elham Alamiri, Khalid Hussain, Sam Wallis, Liat de Vries, Oscar Rubio-Cabezas, Jayne A.L. Houghton, Emma L. Edghill, Ann-Marie Patch, Sian Ellard, Andrew T. Hattersley
Cell Metab. 2014 Jan 7; 19(1): 146–154. doi: 10.1016/j.cmet.2013.11.021
PMCID:
PMC3887257
AbstractArticlePDF–622K
11.
Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice
Sapna Puri, Alejandro García-Núñez, Matthias Hebrok, David A. Cano
PLoS One. 2013; 8(8): e72213. Published online 2013 Aug 20. doi: 10.1371/journal.pone.0072213
PMCID:
PMC3748057
AbstractArticlePDF–1.7M
12.
Pancreas-specific Cre driver lines and considerations for their prudent use
Mark A. Magnuson, Anna B. Osipovich
Cell Metab. Author manuscript; available in PMC 2014 Jul 2.
Published in final edited form as: Cell Metab. 2013 Jul 2; 18(1): 9–20. doi: 10.1016/j.cmet.2013.06.011
PMCID:
PMC3732107
AbstractArticlePDF–717K
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
Transcriptional Regulatory Factor X6 (Rfx6) Increases Gastric Inhibitory Polypeptide (GIP) Expression in Enteroendocrine K-cells and Is Involved in GIP Hypersecretion in High Fat Diet-induced Obesity
Kazuyo Suzuki, Norio Harada, Shunsuke Yamane, Yasuhiko Nakamura, Kazuki Sasaki, Daniela Nasteska, Erina Joo, Kimitaka Shibue, Takanari Harada, Akihiro Hamasaki, Kentaro Toyoda, Kazuaki Nagashima, Nobuya Inagaki
J Biol Chem. 2013 Jan 18; 288(3): 1929–1938. Published online 2012 Nov 28. doi: 10.1074/jbc.M112.423137
PMCID:
PMC3548501
AbstractArticlePDF–2.4M
15.
Convergence of the Insulin and Serotonin Programs in the Pancreatic β-Cell
Yasuharu Ohta, Yasuhiro Kosaka, Nina Kishimoto, Juehu Wang, Stuart B. Smith, Gerard Honig, Hail Kim, Rosa M. Gasa, Nicole Neubauer, Angela Liou, Laurence H. Tecott, Evan S. Deneris, Michael S. German
Diabetes. 2011 Dec; 60(12): 3208–3216. Published online 2011 Nov 13. doi: 10.2337/db10-1192
PMCID:
PMC3219954
AbstractArticlePDF–1.8M
16.
G Protein-Coupled Receptor Signaling and Sphingosine-1-Phosphate Play a Phylogenetically Conserved Role in Endocrine Pancreas Morphogenesis
Ioannis Serafimidis, Scott Heximer, Dimitris Beis, Anthony Gavalas
Mol Cell Biol. 2011 Nov; 31(22): 4442–4453. doi: 10.1128/MCB.05702-11
PMCID:
PMC3209247
AbstractArticlePDF–1.9M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Rfx6 Directs Islet Formation and Insulin Production in Mice and Humans
Stuart B. Smith, Hui-Qi Qu, Nadine Taleb, Nina Kishimoto, David W. Scheel, Yang Lu, Ann-Marie Patch, Rosemary Grabs, Juehu Wang, Francis C. Lynn, Takeshi Miyatsuka, John Mitchell, Rina Seerke, Julie Désir, Serge Vanden Eijnden, Marc Abramowicz, Nadine Kacet, Jacques Weill, Marie-Éve Renard, Mattia Gentile, Inger Hansen, Ken Dewar, Andrew T. Hattersley, Rennian Wang, Maria E. Wilson, Jeffrey D. Johnson, Constantin Polychronakos, Michael S. German
Nature. Author manuscript; available in PMC 2010 Aug 11.
Published in final edited form as: Nature. 2010 Feb 11; 463(7282): 775–780. doi: 10.1038/nature08748
PMCID:
PMC2896718
AbstractArticlePDF–933K

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