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Items: 1 to 20 of 54

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Knockdown of SLC39A14 inhibits glioma progression by promoting erastin-induced ferroptosis SLC39A14 knockdown inhibits glioma progression
Yunwen Zhang, Xinghai Wu, Jiyong Zhu, Ruibin Lu, Yian Ouyang
BMC Cancer. 2023; 23: 1120. Published online 2023 Nov 17. doi: 10.1186/s12885-023-11637-0
PMCID:
PMC10655456
AbstractArticlePDF–9.7M
3.
Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation
Qingli Liu, Supak Jenkitkasemwong, Tamanna Afrin Prami, Shannon Morgan McCabe, Ningning Zhao, Shintaro Hojyo, Toshiyuki Fukada, Mitchell D. Knutson
J Biol Chem. 2023 Aug; 299(8): 105078. Published online 2023 Jul 21. doi: 10.1016/j.jbc.2023.105078
PMCID:
PMC10457451
AbstractArticlePDF–1.0M
4.
Enterocyte-specific deletion of metal transporter Zip14 (Slc39a14) alters intestinal homeostasis through epigenetic mechanisms
Felix R. Jimenez-Rondan, Courtney H. Ruggiero, Kelley Lobean McKinley, Jin Koh, John F. Roberts, Eric W. Triplett, Robert J. Cousins
Am J Physiol Gastrointest Liver Physiol. 2023 Mar 1; 324(3): G159–G176. Published online 2022 Dec 20. doi: 10.1152/ajpgi.00244.2022
PMCID:
PMC9925170
AbstractArticle
5.
Long Noncoding RNA, MicroRNA, Zn Transporter Zip14 (Slc39a14) and Inflammation in Mice
Felix R. Jimenez-Rondan, Courtney H. Ruggiero, Robert J. Cousins
Nutrients. 2022 Dec; 14(23): 5114. Published online 2022 Dec 1. doi: 10.3390/nu14235114
PMCID:
PMC9740689
AbstractArticlePDF–5.6M
6.
Behavioral and neurochemical studies of inherited manganese-induced dystonia-parkinsonism in Slc39a14-knockout mice
Alexander N. Rodichkin, Melissa K. Edler, Jennifer L. McGlothan, Tomás R. Guilarte
Neurobiol Dis. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Neurobiol Dis. 2021 Oct; 158: 105467. Published online 2021 Aug 4. doi: 10.1016/j.nbd.2021.105467
PMCID:
PMC8448284
AbstractArticlePDF–1.8M
7.
Restriction of Manganese Intake Prevents the Onset of Brain Manganese Overload in Zip14−/− Mice
Yuze Wu, Guojun Wei, Ningning Zhao
Int J Mol Sci. 2021 Jul; 22(13): 6773. Published online 2021 Jun 24. doi: 10.3390/ijms22136773
PMCID:
PMC8268934
AbstractArticlePDF–2.5M
8.
Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14
Milankumar Prajapati, Heather L. Conboy, Shintaro Hojyo, Toshiyuki Fukada, Bogdan Budnik, Thomas B. Bartnikas
J Biol Chem. 2021 Jul; 297(1): 100835. Published online 2021 May 26. doi: 10.1016/j.jbc.2021.100835
PMCID:
PMC8214222
AbstractArticlePDF–5.2M
9.
Aberrant Zip14 expression in muscle is associated with cachexia in a Bard1‐deficient mouse model of breast cancer metastasis
Ahmad Rushdi Shakri, Timothy James Zhong, Wanchao Ma, Courtney Coker, Rohaan Hegde, Hanna Scholze, Vanessa Chin, Matthias Szabolcs, Hanina Hibshoosh, Kurenai Tanji, Richard Baer, Anup Kumar Biswas, Swarnali Acharyya
Cancer Med. 2020 Sep; 9(18): 6766–6775. Published online 2020 Jul 30. doi: 10.1002/cam4.3242
PMCID:
PMC7520359
AbstractArticlePDF–895K
10.
Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis
Yingying Yu, Li Jiang, Hao Wang, Zhe Shen, Qi Cheng, Pan Zhang, Jiaming Wang, Qian Wu, Xuexian Fang, Lingyan Duan, Shufen Wang, Kai Wang, Peng An, Tuo Shao, Raymond T. Chung, Shusen Zheng, Junxia Min, Fudi Wang
Blood. 2020 Aug 6; 136(6): 726–739. Prepublished online 2020 May 6. doi: 10.1182/blood.2019002907
PMCID:
PMC7414596
AbstractArticle
11.
Intestine-specific deletion of metal transporter Zip14 (Slc39a14) causes brain manganese overload and locomotor defects of manganism
Tolunay B. Aydemir, Trista L. Thorn, Courtney H. Ruggiero, Marjory Pompilus, Marcelo Febo, Robert J. Cousins
Am J Physiol Gastrointest Liver Physiol. 2020 Apr 1; 318(4): G673–G681. Published online 2020 Jan 31. doi: 10.1152/ajpgi.00301.2019
Correction in:
Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1; 320(4): G557.
PMCID:
PMC7191460
AbstractArticle
12.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis
Ivo Florin Scheiber, Yuze Wu, Shannon Elizabeth Morgan, Ningning Zhao
J Biol Chem. 2019 Jun 7; 294(23): 9147–9160. Published online 2019 Apr 26. doi: 10.1074/jbc.RA119.008762
PMCID:
PMC6556583
AbstractArticlePDF–2.7M
13.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
14.
Metastatic cancers promote cachexia through altered zinc homeostasis in skeletal muscle
Gang Wang, Anup K. Biswas, Wanchao Ma, Manoj Kandpal, Courtney Coker, Paul M. Grandgenett, Michael A. Hollingsworth, Rinku Jain, Kurenai Tanji, Sara Lόpez-Pintado, Alain Borczuk, Doreen Hebert, Supak Jenkitkasemwong, Shintaro Hojyo, Ramana Davuluri, Mitchell D. Knutson, Toshiyuki Fukada, Swarnali Acharyya
Nat Med. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nat Med. 2018 Jun; 24(6): 770–781. Published online 2018 Jun 6. doi: 10.1038/s41591-018-0054-2
PMCID:
PMC6015555
AbstractArticlePDF–1.3M
15.
Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis
Gretl Hendrickx, Vere M. Borra, Ellen Steenackers, Timur A. Yorgan, Christophe Hermans, Eveline Boudin, Jérôme J. Waterval, Ineke D. C. Jansen, Tolunay Beker Aydemir, Niels Kamerling, Geert J. Behets, Christine Plumeyer, Patrick C. D’Haese, Björn Busse, Vincent Everts, Martin Lammens, Geert Mortier, Robert J. Cousins, Thorsten Schinke, Robert J. Stokroos, Johannes J. Manni, Wim Van Hul
PLoS Genet. 2018 Apr; 14(4): e1007321. Published online 2018 Apr 5. doi: 10.1371/journal.pgen.1007321
PMCID:
PMC5903675
AbstractArticlePDF–19M
16.
Disruption of the mouse Slc39a14 gene encoding zinc transporter ZIP14 is associated with decreased bone mass, likely caused by enhanced bone resorption
Sun Sasaki, Manami Tsukamoto, Masaki Saito, Shintaro Hojyo, Toshiyuki Fukada, Masamichi Takami, Tatsuya Furuichi
FEBS Open Bio. 2018 Apr; 8(4): 655–663. Published online 2018 Feb 26. doi: 10.1002/2211-5463.12399
PMCID:
PMC5881542
AbstractArticlePDF–408K
17.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
18.
SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice
Supak Jenkitkasemwong, Adenike Akinyode, Elizabeth Paulus, Ralf Weiskirchen, Shintaro Hojyo, Toshiyuki Fukada, Genesys Giraldo, Jessica Schrier, Armin Garcia, Christopher Janus, Benoit Giasson, Mitchell D. Knutson
Proc Natl Acad Sci U S A. 2018 Feb 20; 115(8): E1769–E1778. Published online 2018 Feb 7. doi: 10.1073/pnas.1720739115
Correction in:
Proc Natl Acad Sci U S A. 2018 May 15; 115(20): E4730.
PMCID:
PMC5828629
AbstractArticlePDF–1.2M
19.
Hypothyroidism induced by loss of the manganese efflux transporter SLC30A10 may be explained by reduced thyroxine production
Chunyi Liu, Steven Hutchens, Thomas Jursa, William Shawlot, Elena V. Polishchuk, Roman S. Polishchuk, Beth K. Dray, Andrea C. Gore, Michael Aschner, Donald R. Smith, Somshuvra Mukhopadhyay
J Biol Chem. 2017 Oct 6; 292(40): 16605–16615. Published online 2017 Aug 31. doi: 10.1074/jbc.M117.804989
PMCID:
PMC5633123
AbstractArticlePDF–2.0M
20.
Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress
Min-Hyun Kim, Tolunay B. Aydemir, Jinhee Kim, Robert J. Cousins
Proc Natl Acad Sci U S A. 2017 Jul 18; 114(29): E5805–E5814. Published online 2017 Jul 3. doi: 10.1073/pnas.1704012114
PMCID:
PMC5530682
AbstractArticlePDF–1.7M

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