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Select item 107775721.

Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice

Xue Bai, Bing Wang, Yiduo Cui, Siqi Tian, Yi Zhang, Linhao You, Yan-Zhong Chang, Guofen Gao

J Neuroinflammation. 2024; 21: 15. Published online 2024 Jan 9. doi: 10.1186/s12974-023-03008-0

PMCID:: PMC10777572

Abstract Article PDF–8.2M

Select item 105322492.

A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice

Sheridan L. Helman, Sarah J. Wilkins, Jennifer C. J. Chan, Gunter Hartel, Daniel F. Wallace, Gregory J. Anderson, David M. Frazer

Int J Mol Sci. 2023 Sep; 24(18): 14379. Published online 2023 Sep 21. doi: 10.3390/ijms241814379

PMCID:: PMC10532249

Abstract Article PDF–2.0M

Select item 104618413.

Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation

Kazuyoshi Ohta, Masahiko Ito, Takeshi Chida, Kenji Nakashima, Satoshi Sakai, Yumi Kanegae, Hideya Kawasaki, Takuya Aoshima, Shuji Takabayashi, Hirotaka Takahashi, Kazuhito Kawata, Ikuo Shoji, Tatsuya Sawasaki, Takafumi Suda, Tetsuro Suzuki

PLoS Pathog. 2023 Aug; 19(8): e1011591. Published online 2023 Aug 16. doi: 10.1371/journal.ppat.1011591

PMCID:: PMC10461841

Abstract Article PDF–2.6M

Select item 104068284.

Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis

Jean-Christophe Deschemin, Céline Ransy, Frédéric Bouillaud, Soonkyu Chung, Bruno Galy, Carole Peyssonnaux, Sophie Vaulont

Sci Rep. 2023; 13: 12794. Published online 2023 Aug 7. doi: 10.1038/s41598-023-39305-0

PMCID:: PMC10406828

Abstract Article PDF–7.0M

Select item 103994465.

Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells

Kevin R. Zhang, Connor S. R. Jankowski, Rayna Marshall, Rohini Nair, Néstor Más Gómez, Ahab Alnemri, Yingrui Liu, Elizabeth Erler, Julia Ferrante, Ying Song, Brent A. Bell, Bailey H. Baumann, Jacob Sterling, Brandon Anderson, Sierra Foshe, Jennifer Roof, Hossein Fazelinia, Lynn A. Spruce, Jen-Zen Chuang, Ching-Hwa Sung, Anuradha Dhingra, Kathleen Boesze-Battaglia, Venkata R. M. Chavali, Joshua D. Rabinowitz, Claire H. Mitchell, Joshua L. Dunaief

Dis Model Mech. 2023 Jul 1; 16(7): dmm050066. Published online 2023 Jul 25. doi: 10.1242/dmm.050066

PMCID:: PMC10399446

Abstract Article

Select item 103568206.

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation

Guillaume Courbon, Jane Joy Thomas, Marta Martinez-Calle, Xueyan Wang, Jadeah Spindler, John Von Drasek, Bridget Hunt-Tobey, Rupal Mehta, Tamara Isakova, Wenhan Chang, John W. M. Creemers, Peng Ji, Aline Martin, Valentin David

Blood. 2023 Jul 6; 142(1): 106–118. Published online 2023 Apr 16. doi: 10.1182/blood.2022018475

PMCID:: PMC10356820

Abstract Article

Select item 103547157.

Low ceruloplasmin levels exacerbate retinal degeneration in a hereditary hemochromatosis model

Brandon D. Anderson, Timothy Lee, Brent Bell, Ying Song, Joshua L. Dunaief

Dis Model Mech. 2023 Jul 1; 16(7): dmm050226. Published online 2023 Jul 13. doi: 10.1242/dmm.050226

PMCID:: PMC10354715

Abstract Article

Select item 98649028.

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice

Edouard Charlebois, Yupeng Li, Victoria Wagner, Kostas Pantopoulos, Martin Olivier

Int J Mol Sci. 2023 Jan; 24(2): 1669. Published online 2023 Jan 14. doi: 10.3390/ijms24021669

PMCID:: PMC9864902

Abstract Article PDF–3.3M

Select item 96327919.

A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin

Airie Kim, Eileen Fung, Sona G. Parikh, Erika V. Valore, Victoria Gabayan, Elizabeta Nemeth, Tomas Ganz

Blood. 2014 Feb 20; 123(8): 1129–1136. Prepublished online 2013 Dec 19. doi: 10.1182/blood-2013-08-521419

PMCID:: PMC9632791

Abstract Article

Select item 946266810.

In iron-deficient mouse pregnancies, erythroferrone contributes to iron mobilization for embryo erythropoiesis

Veena Sangkhae, Vivian Yu, Richard Coffey, Kimberly O. O’Brien, Tomas Ganz, Elizabeta Nemeth

Am J Hematol. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Am J Hematol. 2022 Oct; 97(10): 1348–1358. Published online 2022 Aug 16. doi: 10.1002/ajh.26680

PMCID:: PMC9462668

Abstract Article PDF–1.9M

Select item 934346311.

Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells

Linhao You, Pan-Pan Yu, Tianyu Dong, Wenhuan Guo, Shiyang Chang, Bingjie Zheng, Yunzhe Ci, Fudi Wang, Peng Yu, Guofen Gao, Yan-Zhong Chang

Cell Death Dis. 2022 Aug; 13(8): 667. Published online 2022 Aug 1. doi: 10.1038/s41419-022-05043-w

PMCID:: PMC9343463

Abstract Article PDF–5.5M

Select item 883574312.

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury

Laura E. Diepeveen, Gaby Stegemann, Erwin T. Wiegerinck, Rian Roelofs, Myrthe Naber, Olivier Lóreal, Bart Smeets, Frank Thévenod, Dorine W. Swinkels, Rachel P. L. van Swelm

Int J Mol Sci. 2022 Feb; 23(3): 1352. Published online 2022 Jan 25. doi: 10.3390/ijms23031352

PMCID:: PMC8835743

Abstract Article PDF–2.2M

Select item 875208713.

Aging is associated with increased brain iron through cortex-derived hepcidin expression

Tatsuya Sato, Jason Solomon Shapiro, Hsiang-Chun Chang, Richard A Miller, Hossein Ardehali

eLife. 2022; 11: e73456. Published online 2022 Jan 11. doi: 10.7554/eLife.73456

PMCID:: PMC8752087

Abstract Article PDF–926K

Select item 837046414.

Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice

Caroline A. Enns, Shall Jue, An-Sheng Zhang

Blood. 2021 Aug 12; 138(6): 486–499. Prepublished online 2021 Apr 6. doi: 10.1182/blood.2020009485

PMCID:: PMC8370464

Abstract Article

Select item 835746915.

Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice

Ya-Shuo Zhao, Miao Tan, Ji-Xian Song, Ji-Ren An, Xin-Yue Yang, Wen-Ya Li, Ya-Jing Guo, En-Sheng Ji

Oxid Med Cell Longev. 2021; 2021: 8520967. Published online 2021 Aug 4. doi: 10.1155/2021/8520967

PMCID:: PMC8357469

Abstract Article PDF–3.9M

Select item 824201116.

Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth

Nat Commun. 2021; 12: 4026. Published online 2021 Jun 29. doi: 10.1038/s41467-021-24333-z

PMCID:: PMC8242011

Abstract Article PDF–5.4M

Select item 815704017.

Oral Administration of Ginger-Derived Lipid Nanoparticles and Dmt1 siRNA Potentiates the Effect of Dietary Iron Restriction and Mitigates Pre-Existing Iron Overload in Hamp KO Mice

Xiaoyu Wang, Mingzhen Zhang, Regina R. Woloshun, Yang Yu, Jennifer K. Lee, Shireen R. L. Flores, Didier Merlin, James F. Collins

Nutrients. 2021 May; 13(5): 1686. Published online 2021 May 15. doi: 10.3390/nu13051686

PMCID:: PMC8157040

Abstract Article PDF–2.3M

Select item 810908118.

Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

Hui Zhang, Aifei Wang, Guangsi Shen, Xiao Wang, Gongwen Liu, Fan Yang, Bin Chen, Mingyong Wang, Youjia Xu

Aging (Albany NY) 2021 Apr 30; 13(8): 11296–11314. Published online 2021 Apr 4. doi: 10.18632/aging.202817

PMCID:: PMC8109081

Abstract Article PDF–2.2M

Select item 783375719.

Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin−ferroportin axis

Qifeng Deng, Sidi Yang, Lanqing Sun, Kedi Dong, Yuanyuan Li, Shuyan Wu, Rui Huang

Gut Microbes. 2021; 13(1): 1849996. Published online 2021 Jan 21. doi: 10.1080/19490976.2020.1849996

PMCID:: PMC7833757

Abstract Article PDF–4.1M

Select item 780548420.

Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine COPD model

Elizabeth Perez, Jonathan R. Baker, Silvana Di Giandomenico, Pouneh Kermani, Jacqueline Parker, Kihwan Kim, Jianjun Yang, Peter J. Barnes, Sophie Vaulont, Joseph M. Scandura, Louise E. Donnelly, Heather Stout-Delgado, Suzanne M. Cloonan

J Immunol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: J Immunol. 2020 Nov 1; 205(9): 2489–2498. Published online 2020 Sep 21. doi: 10.4049/jimmunol.1901284

PMCID:: PMC7805484

Abstract Article PDF–1.3M

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