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Select item 92098111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 64694042.

Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of Saccharomyces cerevisiae

Ednalise Santiago-Cartagena, Sahily González-Crespo, Vladimir Vélez, Nelson Martínez, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Zoran Minic, Pearl Akamine, Inoushka Mejías, Luis M. Pérez, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina

G3 (Bethesda) 2019 Apr; 9(4): 1085–1102. Published online 2019 Feb 7. doi: 10.1534/g3.118.200985

PMCID:: PMC6469404

Abstract Article PDF–1.8M

Select item 60941143.

Elesclomol restores mitochondrial function in genetic models of copper deficiency

Shivatheja Soma, Andrew J. Latimer, Haarin Chun, Alison C. Vicary, Shrishiv A. Timbalia, Aren Boulet, Jennifer J. Rahn, Sherine S. L. Chan, Scot C. Leary, Byung-Eun Kim, Jonathan D. Gitlin, Vishal M. Gohil

Proc Natl Acad Sci U S A. 2018 Aug 7; 115(32): 8161–8166. Published online 2018 Jul 23. doi: 10.1073/pnas.1806296115

PMCID:: PMC6094114

Abstract Article PDF–963K

Select item 59225284.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

Select item 57653595.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 57538736.

Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes

Adriana Espinosa-Cantú, Diana Ascencio, Selene Herrera-Basurto, Jiewei Xu, Assen Roguev, Nevan J. Krogan, Alexander DeLuna

Genetics. 2018 Jan; 208(1): 419–431. Published online 2017 Nov 10. doi: 10.1534/genetics.117.300377

PMCID:: PMC5753873

Abstract Article PDF–1.5M

Select item 56618857.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 56002548.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 55551839.

Endoplasmic reticulum–mitochondria junction is required for iron homeostasis

Yong Xue, Stefan Schmollinger, Narsis Attar, Oscar A. Campos, Maria Vogelauer, Michael F. Carey, Sabeeha S. Merchant, Siavash K. Kurdistani

J Biol Chem. 2017 Aug 11; 292(32): 13197–13204. Published online 2017 Jun 21. doi: 10.1074/jbc.M117.784249

PMCID:: PMC5555183

Abstract Article PDF–496K

Select item 505508310.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 494088111.

Transcriptomic response of yeast cells to ATX1 deletion under different copper levels

Ayca Cankorur-Cetinkaya, Serpil Eraslan, Betul Kirdar

BMC Genomics. 2016; 17: 489. Published online 2016 Jul 11. doi: 10.1186/s12864-016-2771-6

PMCID:: PMC4940881

Abstract Article PDF–1.2M

Select item 421474612.

Malfunctioning of the Iron–Sulfur Cluster Assembly Machinery in Saccharomyces cerevisiae Produces Oxidative Stress via an Iron-Dependent Mechanism, Causing Dysfunction in Respiratory Complexes

Mauricio Gomez, Rocío V. Pérez-Gallardo, Luis A. Sánchez, Alma L. Díaz-Pérez, Christian Cortés-Rojo, Victor Meza Carmen, Alfredo Saavedra-Molina, Javier Lara-Romero, Sergio Jiménez-Sandoval, Francisco Rodríguez, José S. Rodríguez-Zavala, Jesús Campos-García

PLoS One. 2014; 9(10): e111585. Published online 2014 Oct 30. doi: 10.1371/journal.pone.0111585

PMCID:: PMC4214746

Abstract Article PDF–2.5M

Select item 383549213.

Mapping the functional yeast ABC transporter interactome

Jamie Snider, Asad Hanif, Mid Eum Lee, Ke Jin, Analyn R. Yu, Chris Graham, Matthew Chuk, Dunja Damjanovic, Marta Wierzbicka, Priscilla Tang, Dina Balderes, Victoria Wong, Matthew Jessulat, Katelyn D. Darowski, Bryan-Joseph San Luis, Igor Shevelev, Stephen L Sturley, Charles Boone, Jack F. Greenblatt, Zhaolei Zhang, Christian M. Paumi, Mohan Babu, Hay-Oak Park, Susan Michaelis, Igor Stagljar

Nat Chem Biol. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Nat Chem Biol. 2013 Sep; 9(9): 565–572. Published online 2013 Jul 7. doi: 10.1038/nchembio.1293

PMCID:: PMC3835492

Abstract Article PDF–1.2M

Select item 353328614.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo A. Sukhai, Swayam Prabha, Rose Hurren, Angela C. Rutledge, Anna Y. Lee, Shrivani Sriskanthadevan, Hong Sun, Xiaoming Wang, Marko Skrtic, Ayesh Seneviratne, Maria Cusimano, Bozhena Jhas, Marcela Gronda, Neil MacLean, Eunice E. Cho, Paul A. Spagnuolo, Sumaiya Sharmeen, Marinella Gebbia, Malene Urbanus, Kolja Eppert, Dilan Dissanayake, Alexia Jonet, Alexandra Dassonville-Klimpt, Xiaoming Li, Alessandro Datti, Pamela S. Ohashi, Jeff Wrana, Ian Rogers, Pascal Sonnet, William Y. Ellis, Seth J. Corey, Connie Eaves, Mark D. Minden, Jean C.Y. Wang, John E. Dick, Corey Nislow, Guri Giaever, Aaron D. Schimmer

J Clin Invest. 2013 Jan 2; 123(1): 315–328. Published online 2012 Dec 3. doi: 10.1172/JCI64180

PMCID:: PMC3533286

Abstract Article PDF–2.1M

Select item 328593315.

La-motif–dependent mRNA association with Slf1 promotes copper detoxification in yeast

Luca Schenk, Dominik M. Meinel, Katja Strässer, André P. Gerber

RNA. 2012 Mar; 18(3): 449–461. doi: 10.1261/rna.028506.111

PMCID:: PMC3285933

Abstract Article PDF–812K

Select item 320904916.

Curcumin Inhibits Growth of Saccharomyces cerevisiae through Iron Chelation

Steven Minear, Allyson F. O'Donnell, Anna Ballew, Guri Giaever, Corey Nislow, Tim Stearns, Martha S. Cyert

Eukaryot Cell. 2011 Nov; 10(11): 1574–1581. doi: 10.1128/EC.05163-11

PMCID:: PMC3209049

Abstract Article PDF–1017K

Select item 308421317.

The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

Peter C. Stirling, Michelle S. Bloom, Tejomayee Solanki-Patil, Stephanie Smith, Payal Sipahimalani, Zhijian Li, Megan Kofoed, Shay Ben-Aroya, Kyungjae Myung, Philip Hieter

PLoS Genet. 2011 Apr; 7(4): e1002057. Published online 2011 Apr 28. doi: 10.1371/journal.pgen.1002057

PMCID:: PMC3084213

Abstract Article PDF–710K

Select item 278735318.

Purification of Nuclear Poly(A)-binding Protein Nab2 Reveals Association with the Yeast Transcriptome and a Messenger Ribonucleoprotein Core Structure

Julien Batisse, Claire Batisse, Aidan Budd, Bettina Böttcher, Ed Hurt

J Biol Chem. 2009 Dec 11; 284(50): 34911–34917. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.062034

PMCID:: PMC2787353

Abstract Article PDF–3.8M

Select item 244714819.

Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109

Jeffrey Fillingham, Judith Recht, Andrea C. Silva, Bernhard Suter, Andrew Emili, Igor Stagljar, Nevan J. Krogan, C. David Allis, Michael-Christopher Keogh, Jack F. Greenblatt

Mol Cell Biol. 2008 Jul; 28(13): 4342–4353. Published online 2008 May 5. doi: 10.1128/MCB.00182-08

PMCID:: PMC2447148

Abstract Article PDF–1.1M

Select item 177089820.

Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies

Brian Haarer, Susan Viggiano, Mathew A. Hibbs, Olga G. Troyanskaya, David C. Amberg

Genes Dev. 2007 Jan 15; 21(2): 148–159. doi: 10.1101/gad.1477507

PMCID:: PMC1770898

Abstract Article PDF–798K

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