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Select item 109416551.

Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes

Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi

J Cell Sci. 2024 Feb 15; 137(4): jcs261625. Published online 2024 Feb 28. doi: 10.1242/jcs.261625

PMCID:: PMC10941655

Abstract Article

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102922103.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 92098114.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 84210715.

A precisely adjustable, variation-suppressed eukaryotic transcriptional controller to enable genetic discovery

Asli Azizoglu, Roger Brent, Fabian Rudolf

eLife. 2021; 10: e69549. Published online 2021 Aug 3. doi: 10.7554/eLife.69549

PMCID:: PMC8421071

Abstract Article PDF–2.4M

Select item 78794826.

Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes

Yeonji Chang, Gyubum Lim, Won-Ki Huh

J Cell Biol. 2021 Apr 5; 220(4): e201912060. Published online 2021 Feb 10. doi: 10.1083/jcb.201912060

PMCID:: PMC7879482

Abstract Article PDF–5.9M

Select item 77187517.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 75074028.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.9M

Select item 74709489.

Rph1 coordinates transcription of ribosomal protein genes and ribosomal RNAs to control cell growth under nutrient stress conditions

Wen-Jie Shu, Runfa Chen, Zhao-Hong Yin, Feng Li, Heng Zhang, Hai-Ning Du

Nucleic Acids Res. 2020 Sep 4; 48(15): 8360–8373. Published online 2020 Jul 3. doi: 10.1093/nar/gkaa558

PMCID:: PMC7470948

Abstract Article PDF–6.1M

Select item 735779010.

Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiae

Koji Kasahara, Risa Nakayama, Yuh Shiwa, Yu Kanesaki, Taichiro Ishige, Hirofumi Yoshikawa, Tetsuro Kokubo

PLoS Genet. 2020 Jun; 16(6): e1008865. Published online 2020 Jun 30. doi: 10.1371/journal.pgen.1008865

PMCID:: PMC7357790

Abstract Article PDF–3.5M

Select item 727317711.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 709155212.

Reactive Carbonyls Induce TOR- and Carbohydrate-Dependent Hormetic Response in Yeast

Halyna Semchyshyn

ScientificWorldJournal. 2020; 2020: 4275194. Published online 2020 Mar 12. doi: 10.1155/2020/4275194

PMCID:: PMC7091552

Abstract Article PDF–466K

Select item 706580513.

Multi-kinase control of environmental stress responsive transcription

Kieran Mace, Joanna Krakowiak, Hana El-Samad, David Pincus

PLoS One. 2020; 15(3): e0230246. Published online 2020 Mar 11. doi: 10.1371/journal.pone.0230246

PMCID:: PMC7065805

Abstract Article PDF–4.4M

Select item 672468414.

Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2

Maria Nieves Martinez Marshall, Anita Emmerstorfer-Augustin, Kristin L. Leskoske, Lydia H. Zhang, Biyun Li, Jeremy Thorner

Mol Biol Cell. 2019 Jun 1; 30(12): 1555–1574. doi: 10.1091/mbc.E18-10-0682

Correction in:: Mol Biol Cell. 2019 Dec 1; 30(25): 3074.

Correction in:: Mol Biol Cell. 2022 Oct 1; 33(12): cor4.

PMCID:: PMC6724684

Abstract Article PDF–3.1M

Select item 669718115.

Ubiquitin regulates TORC1 in yeast Saccharomyces cerevisiae

Kejin Hu, Shuguang Guo, Gonghong Yan, Wenjie Yuan, Yin Zheng, Yu Jiang

Mol Microbiol. Author manuscript; available in PMC 2019 Aug 15.

Published in final edited form as: Mol Microbiol. 2016 Apr; 100(2): 303–314. Published online 2016 Mar 10. doi: 10.1111/mmi.13319

PMCID:: PMC6697181

Abstract Article PDF–2.0M

Select item 666009616.

Genetic variants of TORC1 signaling pathway affect nitrogen consumption in Saccharomyces cerevisiae during alcoholic fermentation

Jennifer Molinet, Francisco A. Cubillos, Francisco Salinas, Gianni Liti, Claudio Martínez

PLoS One. 2019; 14(7): e0220515. Published online 2019 Jul 26. doi: 10.1371/journal.pone.0220515

PMCID:: PMC6660096

Abstract Article PDF–2.6M

Select item 657951817.

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

Vasileios Kargas, Pablo Castro-Hartmann, Norberto Escudero-Urquijo, Kyle Dent, Christine Hilcenko, Carolin Sailer, Gertrude Zisser, Maria J Marques-Carvalho, Simone Pellegrino, Leszek Wawiórka, Stefan MV Freund, Jane L Wagstaff, Antonina Andreeva, Alexandre Faille, Edwin Chen, Florian Stengel, Helmut Bergler, Alan John Warren

eLife. 2019; 8: e44904. Published online 2019 May 22. doi: 10.7554/eLife.44904

PMCID:: PMC6579518

Abstract Article PDF–7.9M

Select item 649953118.

Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast

Yukari Yabuki, Atsuko Ikeda, Misako Araki, Kentaro Kajiwara, Keiko Mizuta, Kouichi Funato

Genetics. 2019 May; 212(1): 175–186. Published online 2019 Mar 1. doi: 10.1534/genetics.118.301874

PMCID:: PMC6499531

Abstract Article PDF–1.8M

Select item 644530119.

Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales

Jing Li, Ignacio Vázquez-García, Karl Persson, Asier González, Jia-Xing Yue, Benjamin Barré, Michael N Hall, Anthony Long, Jonas Warringer, Ville Mustonen, Gianni Liti

Mol Biol Evol. 2019 Apr; 36(4): 691–708. Published online 2019 Jan 17. doi: 10.1093/molbev/msz006