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Select item 110146571.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 108865302.

Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth

Fatima Wazin, Frank J. Lovicu

Cells. 2024 Feb; 13(4): 290. Published online 2024 Feb 6. doi: 10.3390/cells13040290

PMCID:: PMC10886530

Abstract Article PDF–14M

Select item 103756773.

Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development

Huijuan Dai, Wenting Xu, Lulu Wang, Xiao Li, Xiaonan Sheng, Lei Zhu, Ye Li, Xinrui Dong, Weihang Zhou, Chenyu Han, Yan Mao, Linli Yao

Breast Cancer Res. 2023; 25: 90. Published online 2023 Jul 28. doi: 10.1186/s13058-023-01683-8

PMCID:: PMC10375677

Abstract Article PDF–5.2M

Select item 102682404.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 99820405.

Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13

Michael A. Schumacher, Cambrian Y. Liu, Kay Katada, Megan H. Thai, Jonathan J. Hsieh, Britany J. Hansten, Amanda Waddell, Michael J. Rosen, Mark R. Frey

Cell Mol Gastroenterol Hepatol. 2023; 15(4): 971–984. Published online 2022 Nov 19. doi: 10.1016/j.jcmgh.2022.11.004

PMCID:: PMC9982040

Abstract Article PDF–3.8M

Select item 95472976.

Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching

Wei Wei, Xiaofang Tang, Ning Jiang, Chao Ni, Hua He, Shenfei Sun, Meng Yu, Chuyue Yu, Mengdi Qiu, Dong Yan, Zhaocai Zhou, Yuanlin Song, Hanmin Liu, Bing Zhao, Xinhua Lin

J Biol Chem. 2022 Oct; 298(10): 102490. Published online 2022 Sep 14. doi: 10.1016/j.jbc.2022.102490

PMCID:: PMC9547297

Abstract Article PDF–6.1M

Select item 94707067.

A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes

Gisela Altés, Marta Vaquero, Sara Cuesta, Carlos Anerillas, Anna Macià, Carme Espinet, Joan Ribera, Saverio Bellusci, Ophir D. Klein, Andree Yeramian, Xavi Dolcet, Joaquim Egea, Mario Encinas

Cell Mol Life Sci. 2022; 79(10): 514. Published online 2022 Sep 13. doi: 10.1007/s00018-022-04546-1

PMCID:: PMC9470706

Abstract Article PDF–4.6M

Select item 93810988.

Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression

Rachana Patel, Catriona A. Ford, Lisa Rodgers, Linda K. Rushworth, Janis Fleming, Ernest Mui, Tong Zhang, David Watson, Victoria Lynch, Gillian Mackay, David Sumpton, Owen J. Sansom, Johan Vande Voorde, Hing Y. Leung

Cancer Res. 2022 Jul 18; 82(14): 2565–2575. Published online 2022 Jun 8. doi: 10.1158/0008-5472.CAN-21-1301

PMCID:: PMC9381098

Abstract Article PDF–1.4M

Select item 91815419.

Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway

Guangying Yang, Shan Lu, Jia Jiang, Jun Weng, Xiaomei Zeng

Int J Mol Sci. 2022 Jun; 23(11): 6014. Published online 2022 May 27. doi: 10.3390/ijms23116014

PMCID:: PMC9181541

Abstract Article PDF–4.4M

Select item 916859910.

Activation of PI3K/p110α in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation

Haiting Dai, Mingli Zhu, Wenya Li, Guohui Si, Yiming Xing

Front Cell Dev Biol. 2022; 10: 880206. Published online 2022 May 23. doi: 10.3389/fcell.2022.880206

PMCID:: PMC9168599

Abstract Article PDF–4.4M

Select item 899508711.

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac

Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson

Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131

PMCID:: PMC8995087

Abstract Article

Select item 893546412.

Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog

M. Seppala, B. Thivichon-Prince, G.M. Xavier, N. Shaffie, I. Sangani, A.A. Birjandi, J. Rooney, J.N.S. Lau, R. Dhaliwal, O. Rossi, M.A. Riaz, D. Stonehouse-Smith, Y. Wang, S.N. Papageorgiou, L. Viriot, M.T. Cobourne

J Dent Res. 2022 Apr; 101(4): 473–482. Published online 2021 Nov 19. doi: 10.1177/00220345211049403

PMCID:: PMC8935464

Abstract Article PDF–4.4M

Select item 861731113.

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

William E. Tidyman, Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen

Dis Model Mech. 2022 Feb 1; 15(2): dmm049166. Published online 2021 Nov 19. doi: 10.1242/dmm.049166

PMCID:: PMC8617311

Abstract Article

Select item 858032614.

Phase transition specified by a binary code patterns the vertebrate eye cup

Revathi Balasubramanian, Xuanyu Min, Peter M. J. Quinn, Quentin Lo Giudice, Chenqi Tao, Karina Polanco, Neoklis Makrides, John Peregrin, Michael Bouaziz, Yingyu Mao, Qian Wang, Bruna L. da Costa, Diego Buenaventura, Fen Wang, Liang Ma, Stephen H. Tsang, Pierre J. Fabre, Xin Zhang

Sci Adv. 2021 Nov; 7(46): eabj9846. Published online 2021 Nov 10. doi: 10.1126/sciadv.abj9846

PMCID:: PMC8580326

Abstract Article PDF–3.8M

Select item 831323915.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 817138116.

Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

Nobuyuki Kawamura, Katsuyoshi Takaoka, Hiroshi Hamada, Anna-Katerina Hadjantonakis, Ge-Hong Sun-Wada, Yoh Wada

Cell Rep. Author manuscript; available in PMC 2021 Jun 2.

Published in final edited form as: Cell Rep. 2020 Jun 9; 31(10): 107733. doi: 10.1016/j.celrep.2020.107733

PMCID:: PMC8171381

Abstract Article PDF–1.3M

Select item 797186517.

Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases

Anand Sripada, Kapil Sirohi, Lidia Michalec, Lei Guo, Jerome T. McKay, Sangya Yadav, Mukesh Verma, James Good, Donald Rollins, Magdalena M. Gorska, Rafeul Alam

PLoS Biol. 2021 Mar; 19(3): e3001063. Published online 2021 Mar 8. doi: 10.1371/journal.pbio.3001063

PMCID:: PMC7971865

Abstract Article PDF–4.9M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 786491619.

Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33

Michael A. Schumacher, Jonathan J. Hsieh, Cambrian Y. Liu, Keren L. Appel, Amanda Waddell, Dana Almohazey, Kay Katada, Jessica K. Bernard, Edie B. Bucar, Safina Gadeock, Kathryn M. Maselli, M. Kay Washington, Tracy C. Grikscheit, David Warburton, Michael J. Rosen, Mark R. Frey

Nat Commun. 2021; 12: 836. Published online 2021 Feb 5. doi: 10.1038/s41467-021-21113-7

PMCID:: PMC7864916

Abstract Article PDF–5.3M

Select item 781571220.

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy

A. Hörnblad, S. Bastide, K. Langenfeld, F. Langa, F. Spitz

Nat Commun. 2021; 12: 439. Published online 2021 Jan 19. doi: 10.1038/s41467-020-20714-y

PMCID:: PMC7815712

Abstract Article PDF–3.4M

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