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Select item 109727191.

Neural Wiskott-Aldrich syndrome protein (N-WASP) promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2

HYUNG SUN KIM, YUN SUN LEE, SEUNG MYUNG DONG, HYO JUNG KIM, DA EUN LEE, HYEON WOONG KANG, MYEONG JIN KIM, JOON SEONG PARK

Oncol Res. 2024; 32(4): 615–624. Published online 2024 Mar 20. doi: 10.32604/or.2024.044029

PMCID:: PMC10972719

Abstract Article PDF–8.5M

Select item 107157342.

N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters

Anshuman Bhanja, Margaret K Seeley-Fallen, Michelle Lazzaro, Arpita Upadhyaya, Wenxia Song

eLife. 2023; 12: RP87833. Published online 2023 Dec 12. doi: 10.7554/eLife.87833

PMCID:: PMC10715734

Abstract Article PDF–15M

Select item 105265183.

Conditional Knockout of N-WASP Enhanced the Formation of Keratinizing Squamous Cell Carcinoma Induced by KRas^G12D

Pazhanichamy Kalailingam, Apoorva Verma, Ying Hui Lee, Thirumaran Thanabalu

Cancers (Basel) 2023 Sep; 15(18): 4455. Published online 2023 Sep 7. doi: 10.3390/cancers15184455

PMCID:: PMC10526518

Abstract Article PDF–3.9M

Select item 103078524.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99536715.

nWASP Inhibition Increases Wound Healing via TrKb/PLCγ Signalling

Bethan A. Frugtniet, Fiona Ruge, Andrew J. Sanders, Sioned Owen, Keith G. Harding, Wen G. Jiang, Tracey A. Martin

Biomolecules. 2023 Feb; 13(2): 379. Published online 2023 Feb 17. doi: 10.3390/biom13020379

PMCID:: PMC9953671

Abstract Article PDF–6.0M

Select item 90156996.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 81746507.

Neuronal Wiskott-Aldrich syndrome protein regulates Pseudomonas aeruginosa-induced lung vascular permeability through the modulation of actin cytoskeletal dynamics

Pulin Che, Brant M. Wagener, Xueke Zhao, Angela P. Brandon, Cilina A. Evans, Guo-Qiang Cai, Rui Zhao, Zhi-Xiang Xu, Xiaosi Han, Jean-Francois Pittet, Qiang Ding

FASEB J. Author manuscript; available in PMC 2021 Jun 3.

Published in final edited form as: FASEB J. 2020 Feb; 34(2): 3305–3317. Published online 2020 Jan 9. doi: 10.1096/fj.201902915R

PMCID:: PMC8174650

Abstract Article PDF–1.7M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74071999.

The WAVE Regulatory Complex Is Required to Balance Protrusion and Adhesion in Migration

Jamie A. Whitelaw, Karthic Swaminathan, Frieda Kage, Laura M. Machesky

Cells. 2020 Jul; 9(7): 1635. Published online 2020 Jul 7. doi: 10.3390/cells9071635

PMCID:: PMC7407199

Abstract Article PDF–6.7M

Select item 740627410.

N-Wasp Regulates Oligodendrocyte Myelination

Christina Katanov, Nurit Novak, Anya Vainshtein, Ofra Golani, Jeffery L. Dupree, Elior Peles

J Neurosci. 2020 Aug 5; 40(32): 6103–6111. doi: 10.1523/JNEUROSCI.0912-20.2020

Correction in:: J Neurosci. 2024 May 1; 44(18): e0612242024.

PMCID:: PMC7406274

Abstract Article PDF–4.7M

Select item 725952011.

Loss of Wasl improves pancreatic cancer outcome

Ana Hidalgo-Sastre, Judit Desztics, Zahra Dantes, Katharina Schulte, Hilal Kabadayi Ensarioglu, Blessing Bassey-Archibong, Rupert Öllinger, Thomas Engleiter, Lyndsay Rayner, Henrik Einwächter, Juliet M. Daniel, Ali Sameer Abdulghani Altaee, Katia Steiger, Marina Lesina, Roland Rad, Maximilian Reichert, Guido von Figura, Jens T. Siveke, Roland M. Schmid, Clara Lubeseder-Martellato

JCI Insight. 2020 May 21; 5(10): e127275. Published online 2020 May 21. doi: 10.1172/jci.insight.127275

PMCID:: PMC7259520

Abstract Article PDF–62M

Select item 697852512.

WASP family proteins regulate the mobility of the B cell receptor during signaling activation

Ivan Rey-Suarez, Brittany A. Wheatley, Peter Koo, Anshuman Bhanja, Zhou Shu, Simon Mochrie, Wenxia Song, Hari Shroff, Arpita Upadhyaya

Nat Commun. 2020; 11: 439. Published online 2020 Jan 23. doi: 10.1038/s41467-020-14335-8

PMCID:: PMC6978525

Abstract Article PDF–3.2M

Select item 667526113.

WAVE1 Is Required for Oligodendrocyte Morphogenesis and Normal CNS Myelination

Hyun-Ju Kim, Allitia B. DiBernardo, Jacob A. Sloane, Matthew N. Rasband, David Solomon, Bela Kosaras, Seung P. Kwak, Timothy K. Vartanian

J Neurosci. 2006 May 24; 26(21): 5849–5859. doi: 10.1523/JNEUROSCI.4921-05.2006

PMCID:: PMC6675261

Abstract Article PDF–1.8M

Select item 605726914.

A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits

Leonardo Almeida-Souza, Rene A.W. Frank, Javier García-Nafría, Adeline Colussi, Nushan Gunawardana, Christopher M. Johnson, Minmin Yu, Gillian Howard, Byron Andrews, Yvonne Vallis, Harvey T. McMahon

Cell. 2018 Jul 12; 174(2): 325–337.e14. doi: 10.1016/j.cell.2018.05.020

PMCID:: PMC6057269

Abstract Article

Select item 603301215.

Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis

Hayley T Morris, Loic Fort, Heather J Spence, Rachana Patel, David F Vincent, James H Park, Scott B Snapper, Francis A Carey, Owen J Sansom, Laura M Machesky

J Pathol. 2018 Jul; 245(3): 337–348. Published online 2018 May 28. doi: 10.1002/path.5086

PMCID:: PMC6033012

Abstract Article PDF–2.9M

Select item 589736316.

Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

Hui Li, Qi Yao, Alberto Garcia Mariscal, Xudong Wu, Justus Hülse, Esben Pedersen, Kristian Helin, Ari Waisman, Caroline Vinkel, Simon Francis Thomsen, Alexandra Avgustinova, Salvador Aznar Benitah, Paola Lovato, Hanne Norsgaard, Mette Sidsel Mortensen, Lone Veng, Björn Rozell, Cord Brakebusch

Nat Commun. 2018; 9: 1420. Published online 2018 Apr 12. doi: 10.1038/s41467-018-03704-z

PMCID:: PMC5897363

Abstract Article PDF–5.6M

Select item 554474317.

Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

Pazhanichamy Kalailingam, Hui Bing Tan, Neeraj Jain, Ming Keat Sng, Jeremy Soon Kiat Chan, Nguan Soon Tan, Thirumaran Thanabalu

Sci Rep. 2017; 7: 7311. Published online 2017 Aug 4. doi: 10.1038/s41598-017-07125-8

PMCID:: PMC5544743

Abstract Article PDF–11M

Select item 523382418.

Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions

Clara Lubeseder-Martellato, Katharina Alexandrow, Ana Hidalgo-Sastre, Irina Heid, Sophie Luise Boos, Thomas Briel, Roland M. Schmid, Jens T. Siveke

EBioMedicine. 2017 Feb; 15: 90–99. Published online 2016 Dec 24. doi: 10.1016/j.ebiom.2016.12.013

PMCID:: PMC5233824

Abstract Article PDF–2.4M

Select item 513356019.

Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure

Neeraj Jain, Pazhanichamy Kalailingam, Kai Wei Tan, Hui Bing Tan, Ming Keat Sng, Jeremy Soon Kiat Chan, Nguan Soon Tan, Thirumaran Thanabalu

Sci Rep. 2016; 6: 38109. Published online 2016 Dec 2. doi: 10.1038/srep38109

PMCID:: PMC5133560

Abstract Article PDF–2.0M

Select item 490429020.

Neuronal Wiskott–Aldrich syndrome protein regulates TGF-β1–mediated lung vascular permeability

Brant M. Wagener, Meng Hu, Anni Zheng, Xueke Zhao, Pulin Che, Angela Brandon, Naseem Anjum, Scott Snapper, Judy Creighton, Jun-Lin Guan, Qimei Han, Guo-Qiang Cai, Xiaosi Han, Jean-Francois Pittet, Qiang Ding

FASEB J. 2016 Jul; 30(7): 2557–2569. Published online 2016 Mar 29. doi: 10.1096/fj.201600102R

PMCID:: PMC4904290

Abstract Article

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