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Select item 104642771.

PIWIL2 restrains the progression of thyroid cancer via interaction with miR-146a-3p

Xiaoxiao Lu, Qingyun Zhu, Hong Du, Mingjun Gu, Xiangqi Li

BMC Endocr Disord. 2023; 23: 184. Published online 2023 Aug 29. doi: 10.1186/s12902-023-01416-0

Correction in:: BMC Endocr Disord. 2024; 24: 255.

PMCID:: PMC10464277

Abstract Article PDF–7.3M

Select item 99003422.

Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus

Caterina Gasperini, Kiril Tuntevski, Silvia Beatini, Roberta Pelizzoli, Amanda Lo Van, Damiano Mangoni, Rosa M Cossu, Giovanni Pascarella, Paolo Bianchini, Pascal Bielefeld, Margherita Scarpato, Meritxell Pons‐Espinal, Remo Sanges, Alberto Diaspro, Carlos P Fitzsimons, Piero Carninci, Stefano Gustincich, Davide De Pietri Tonelli

EMBO Rep. 2023 Feb; 24(2): e53801. Published online 2022 Dec 6. doi: 10.15252/embr.202153801

PMCID:: PMC9900342

Abstract Article PDF–3.3M

Select item 92789863.

EED is required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad

Matthew G. Lowe, Ming-Ren Yen, Fei-man Hsu, Linzi Hosohama, Zhongxun Hu, Tsotne Chitiashvili, Timothy Hunt, Isaac Gorgy, Matthew Bernard, Sissy Wamaitha, Pao-Yang Chen, Amander T. Clark

Dev Cell. Author manuscript; available in PMC 2023 Jun 20.

Published in final edited form as: Dev Cell. 2022 Jun 20; 57(12): 1482–1495.e5. Published online 2022 Jun 8. doi: 10.1016/j.devcel.2022.05.012

PMCID:: PMC9278986

Abstract Article PDF–1.6M

Select item 86743284.

SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline

Toshiaki Ito, Atsuki Osada, Masami Ohta, Kana Yokota, Akira Nishiyama, Yuichi Niikura, Tomohiko Tamura, Yoichi Sekita, Tohru Kimura

Sci Rep. 2021; 11: 24074. Published online 2021 Dec 15. doi: 10.1038/s41598-021-03538-8

PMCID:: PMC8674328

Abstract Article PDF–5.3M

Select item 85169555.

MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells

Kanako Kojima-Kita, Satomi Kuramochi-Miyagawa, Manabu Nakayama, Haruhiko Miyata, Steven E. Jacobsen, Masahito Ikawa, Haruhiko Koseki, Toru Nakano

Sci Rep. 2021; 11: 20472. Published online 2021 Oct 14. doi: 10.1038/s41598-021-98940-7

PMCID:: PMC8516955

Abstract Article PDF–2.3M

Select item 82017646.

The Rhox gene cluster suppresses germline LINE1 transposition

Kun Tan, Matthew E. Kim, Hye-Won Song, David Skarbrevik, Eric Babajanian, Tracy A. Bedrosian, Fred H. Gage, Miles F. Wilkinson

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2024785118. Published online 2021 Jun 3. doi: 10.1073/pnas.2024785118

PMCID:: PMC8201764

Abstract Article PDF–2.0M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76122478.

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation

Ansgar Zoch, Tania Auchynnikava, Rebecca V. Berrens, Yuka Kabayama, Theresa Schöpp, Madeleine Heep, Lina Vasiliauskaitė, Yuvia A. Pérez-Rico, Atlanta G. Cook, Alena Shkumatava, Juri Rappsilber, Robin C. Allshire, Dónal O’Carroll

Nature. Author manuscript; available in PMC 2022 Jan 21.

Published in final edited form as: Nature. 2020 Aug 1; 584(7822): 635–639. Published online 2020 Jul 16. doi: 10.1038/s41586-020-2557-5

PMCID:: PMC7612247

Abstract Article PDF–5.7M

Select item 75482809.

PIWIL-2 and piRNAs are regularly expressed in epithelia of the skin and their expression is related to differentiation

Johannes Pammer, Heidi Rossiter, Martin Bilban, Leopold Eckhart, Maria Buchberger, Laura Monschein, Michael Mildner

Arch Dermatol Res. 2020; 312(10): 705–714. Published online 2020 Mar 12. doi: 10.1007/s00403-020-02052-7

PMCID:: PMC7548280

Abstract Article PDF–1.1M

Select item 726314110.

TEX15 associates with MILI and silences transposable elements in male germ cells

Fang Yang, Yemin Lan, Radha Raman Pandey, David Homolka, Shelley L. Berger, Ramesh S. Pillai, Marisa S. Bartolomei, P. Jeremy Wang

Genes Dev. 2020 Jun 1; 34(11-12): 745–750. doi: 10.1101/gad.335489.119

PMCID:: PMC7263141

Abstract Article PDF–3.1M

Select item 696519311.

Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity

Marla E. Tharp, Safia Malki, Alex Bortvin

Nat Commun. 2020; 11: 330. Published online 2020 Jan 16. doi: 10.1038/s41467-019-14055-8

PMCID:: PMC6965193

Abstract Article PDF–2.7M

Select item 694438212.

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Eliska Taborska, Josef Pasulka, Radek Malik, Filip Horvat, Irena Jenickova, Zoe Jelić Matošević, Petr Svoboda

PLoS Genet. 2019 Dec; 15(12): e1008261. Published online 2019 Dec 20. doi: 10.1371/journal.pgen.1008261

PMCID:: PMC6944382

Abstract Article PDF–2.6M

Select item 642012913.

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

Marcos Morgan, Yuka Kabayama, Christian Much, Ivayla Ivanova, Monica Di Giacomo, Tatsiana Auchynnikava, Jack Michael Monahan, Dimitrios Michael Vitsios, Lina Vasiliauskaitė, Stefano Comazzetto, Juri Rappsilber, Robin Campbell Allshire, Bo Torben Porse, Anton James Enright, Dónal O’Carroll

Cell Res. 2019 Mar; 29(3): 221–232. Published online 2019 Jan 7. doi: 10.1038/s41422-018-0128-1

PMCID:: PMC6420129

Abstract Article PDF–2.9M

Select item 641193814.

Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis

Deqiang Ding, Jiali Liu, Kunzhe Dong, Ashley F Melnick, Keith E Latham, Chen Chen

Nucleic Acids Res. 2019 Mar 18; 47(5): 2594–2608. Published online 2018 Dec 22. doi: 10.1093/nar/gky1281

PMCID:: PMC6411938

Abstract Article PDF–12M

Select item 613092015.

A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals

Ildar Gainetdinov, Cansu Colpan, Amena Arif, Katharine Cecchini, Phillip D. Zamore

Mol Cell. Author manuscript; available in PMC 2019 Sep 6.

Published in final edited form as: Mol Cell. 2018 Sep 6; 71(5): 775–790.e5. doi: 10.1016/j.molcel.2018.08.007

PMCID:: PMC6130920

Abstract Article PDF–1.1M

Select item 589860916.

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

Lina Vasilauskaite, Dimitrios Vitsios, Rebecca Berrens, Claudia Carrieri, Wolf Reik, Anton J Enright, Dónal O’Carroll

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Apr 13.

Published in final edited form as: Nat Struct Mol Biol. 2017 Jul; 24(7): 604–606. Published online 2017 May 22. doi: 10.1038/nsmb.3413

PMCID:: PMC5898609

Abstract Article PDF–906K

Select item 589140017.

Mouse GTSF1 is an essential factor for secondary piRNA biogenesis

Takuji Yoshimura, Toshiaki Watanabe, Satomi Kuramochi‐Miyagawa, Noriaki Takemoto, Yusuke Shiromoto, Akihiko Kudo, Masami Kanai‐Azuma, Fumi Tashiro, Satsuki Miyazaki, Ami Katanaya, Shinichiro Chuma, Jun‐ichi Miyazaki

EMBO Rep. 2018 Apr; 19(4): e42054. Published online 2018 Feb 7. doi: 10.15252/embr.201642054

PMCID:: PMC5891400

Abstract Article PDF–1.8M

Select item 558963018.

Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

Yilu Lu, Xulei Zheng, Wei Hu, Shasha Bian, Zhiwei Zhang, Dachang Tao, Yunqiang Liu, Yongxin Ma

Oncotarget. 2017 Aug 15; 8(33): 54913–54924. Published online 2017 Jul 4. doi: 10.18632/oncotarget.18973

PMCID:: PMC5589630

Abstract Article PDF–3.9M

Select item 548118619.

Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function

Joanna M. Wenda, David Homolka, Zhaolin Yang, Pietro Spinelli, Ravi Sachidanandam, Radha Raman Pandey, Ramesh S. Pillai

Dev Cell. 2017 Jun 19; 41(6): 623–637.e9. doi: 10.1016/j.devcel.2017.05.021

PMCID:: PMC5481186

Abstract Article

Select item 546099920.

A transit-amplifying population underpins the efficient regenerative capacity of the testis

Claudia Carrieri, Stefano Comazzetto, Amit Grover, Marcos Morgan, Andreas Buness, Claus Nerlov, Dónal O’Carroll

J Exp Med. 2017 Jun 5; 214(6): 1631–1641. doi: 10.1084/jem.20161371

PMCID:: PMC5460999

Abstract Article PDF–1.6M

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