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Select item 111927191.

MiR-503-5p alleviates peripheral neuropathy-induced neuropathic pain in T2DM mice by regulating SEPT9 to inhibit astrocyte activation

Yuqing Guo, Jingyang Zeng, Yuanzhao Zhuang, Changcheng Jiang, Wenqin Xie

Sci Rep. 2024; 14: 14361. Published online 2024 Jun 21. doi: 10.1038/s41598-024-65096-z

PMCID:: PMC11192719

Abstract Article PDF–6.7M

Select item 104990202.

Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals

Benjamin T. Jones, Jaeil Han, He Zhang, Robert E. Hammer, Bret M. Evers, Dinesh Rakheja, Asha Acharya, Joshua T. Mendell

Genes Dev. 2023 Jul 1; 37(13-14): 661–674. doi: 10.1101/gad.350906.123

PMCID:: PMC10499020

Abstract Article PDF–6.2M

Select item 101914413.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 100195704.

A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions

Rujin Huang, Jinyang Liu, Xi Chen, Ying Zhi, Shuangyuan Ding, Jia Ming, Yulin Li, Yangming Wang, Jie Na

Protein Cell. 2023 Feb; 14(2): 153–157. Published online 2022 May 28. doi: 10.1093/procel/pwac019

PMCID:: PMC10019570

Article PDF–3.5M

Select item 96755755.

Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury

Ting-Xi Yu, Sudhakar Kalakonda, Xiangzheng Liu, Naomi Han, Hee K. Chung, Lan Xiao, Jaladanki N. Rao, Tong-Chuan He, Jean-Pierre Raufman, Jian-Ying Wang

JCI Insight. 2022 Oct 10; 7(19): e156612. Published online 2022 Oct 10. doi: 10.1172/jci.insight.156612

PMCID:: PMC9675575

Abstract Article PDF–14M

Select item 91300016.

MicroRNA-503 Exacerbates Myocardial Ischemia/Reperfusion Injury via Inhibiting PI3K/Akt- and STAT3-Dependent Prosurvival Signaling Pathways

Yanjing He, Yin Cai, Tianhao Sun, Liangqing Zhang, Michael G. Irwin, Aimin Xu, Zhengyuan Xia

Oxid Med Cell Longev. 2022; 2022: 3449739. Published online 2022 May 17. doi: 10.1155/2022/3449739

PMCID:: PMC9130001

Abstract Article PDF–2.5M

Select item 87180887.

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

Rui Liang, Xiaopeng Shen, Fan Wang, Xin Wang, Alex DesJarlais, Anam Syed, Raymond Saba, Zhi Tan, Fang Yu, Xuan Ji, Shreesti Shrestha, Yinghong Ren, Jin Yang, Yoonjung Park, Robert J. Schwartz, Benjamin Soibam, Bradley K. McConnell, M. David Stewart, Ashok Kumar, Yu Liu

J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 2174–2186. Published online 2021 Oct 26. doi: 10.1002/jcsm.12827

PMCID:: PMC8718088

Abstract Article PDF–9.5M

Select item 86471488.

miR‐424/503 modulates Wnt/β‐catenin signaling in the mammary epithelium by targeting LRP6

Erin A Nekritz, Ruth Rodriguez‐Barrueco, Koon‐Kiu Yan, Meredith L Davis, Rachel L Werner, Laura Devis‐Jauregui, Partha Mukhopadhyay, Jiyang Yu, David Llobet‐Navas, Jose Silva

EMBO Rep. 2021 Dec 6; 22(12): e53201. Published online 2021 Oct 11. doi: 10.15252/embr.202153201

PMCID:: PMC8647148

Abstract Article PDF–1.4M

Select item 75821389.

miR-322/-503 rescues myoblast defects in myotonic dystrophy type 1 cell model by targeting CUG repeats

Xiaopeng Shen, Feng Xu, Meng Li, Shen Wu, Jingyi Zhang, Ao Wang, Lei Xu, Yu Liu, Guoping Zhu

Cell Death Dis. 2020 Oct; 11(10): 891. Published online 2020 Oct 22. doi: 10.1038/s41419-020-03112-6

PMCID:: PMC7582138

Abstract Article PDF–3.4M

Select item 691874210.

Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs

Matthew R. George, Qiming Duan, Abigail Nagle, Irfan S. Kathiriya, Yu Huang, Kavitha Rao, Saptarsi M. Haldar, Benoit G. Bruneau

Development. 2019 Dec 1; 146(23): dev185314. Published online 2019 Dec 9. doi: 10.1242/dev.185314

PMCID:: PMC6918742

Abstract Article

Select item 545141211.

A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis

Aram Lee, Irinna Papangeli, Youngsook Park, Ha-neul Jeong, Jihea Choi, Hyesoo Kang, Ha-neul Jo, Jongmin Kim, Hyung J. Chun

Sci Rep. 2017; 7: 2528. Published online 2017 May 31. doi: 10.1038/s41598-017-02852-4

PMCID:: PMC5451412

Abstract Article PDF–5.7M

Select item 539305112.

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

Ruth Rodriguez-Barrueco, Erin A. Nekritz, François Bertucci, Jiyang Yu, Felix Sanchez-Garcia, Tizita Z. Zeleke, Andrej Gorbatenko, Daniel Birnbaum, Elena Ezhkova, Carlos Cordon-Cardo, Pascal Finetti, David Llobet-Navas, Jose M. Silva

Genes Dev. 2017 Mar 15; 31(6): 553–566. doi: 10.1101/gad.292318.116

PMCID:: PMC5393051

Abstract Article PDF–1.7M

Select item 500328113.

miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification

Xiaopeng Shen, Benjamin Soibam, Ashley Benham, Xueping Xu, Mani Chopra, Xiaoping Peng, Wei Yu, Wenjing Bao, Rui Liang, Alon Azares, Peijun Liu, Preethi H. Gunaratne, Mark Mercola, Austin J. Cooney, Robert J. Schwartz, Yu Liu

Proc Natl Acad Sci U S A. 2016 Aug 23; 113(34): 9551–9556. Published online 2016 Aug 10. doi: 10.1073/pnas.1608256113

PMCID:: PMC5003281

Abstract Article PDF–1.1M

Select item 475946414.

MicroRNA‐503 promotes angiotensin II‐induced cardiac fibrosis by targeting Apelin‐13

Yuhong Zhou, Lin Deng, Dandan Zhao, Lanlan Chen, Zhen Yao, Xiaowei Guo, Xue Liu, Lifang Lv, Bing Leng, Wei Xu, Guofen Qiao, Hongli Shan

J Cell Mol Med. 2016 Mar; 20(3): 495–505. Published online 2016 Jan 12. doi: 10.1111/jcmm.12754

PMCID:: PMC4759464

Abstract Article PDF–669K

Select item 468213515.

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response

Ananya Gupta, Muhammad Mosaraf Hossain, Danielle E. Read, Claudio Hetz, Afshin Samali, Sanjeev Gupta

Sci Rep. 2015; 5: 18304. Published online 2015 Dec 17. doi: 10.1038/srep18304

PMCID:: PMC4682135

Abstract Article PDF–2.1M

Select item 447938116.

Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression

Irene Forno, Stefano Ferrero, Maria Veronica Russo, Giacomo Gazzano, Sara Giangiobbe, Emanuele Montanari, Alberto Del Nero, Bernardo Rocco, Giancarlo Albo, Lucia R. Languino, Dario C. Altieri, Valentina Vaira, Silvano Bosari

PLoS One. 2015; 10(6): e0130060. Published online 2015 Jun 24. doi: 10.1371/journal.pone.0130060

PMCID:: PMC4479381

Abstract Article PDF–7.0M

Select item 401548817.

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland

David Llobet-Navas, Ruth Rodríguez-Barrueco, Verónica Castro, Alejandro P. Ugalde, Pavel Sumazin, Damian Jacob-Sendler, Berna Demircan, Mireia Castillo-Martín, Preeti Putcha, Netonia Marshall, Patricia Villagrasa, Joseph Chan, Félix Sanchez-Garcia, Dana Pe’er, Raul Rabadán, Antonio Iavarone, Carlos Cordón-Cardó, Andrea Califano, Carlos López-Otín, Elena Ezhkova, Jose M. Silva

Genes Dev. 2014 Apr 1; 28(7): 765–782. doi: 10.1101/gad.237404.114

PMCID:: PMC4015488

Abstract Article PDF–3.2M

Select item 362041518.

A Common MicroRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ with Normal Umbrella Cells

Angela Y. Jia, Mireia Castillo-Martin, Josep Domingo-Domenech, Dennis M. Bonal, Marta Sánchez-Carbayo, Jose M. Silva, Carlos Cordon-Cardo

Am J Pathol. 2013 Apr; 182(4): 1171–1179. doi: 10.1016/j.ajpath.2013.01.006

PMCID:: PMC3620415

Abstract Article PDF–1.2M

Select item 324203219.

A resource of vectors and ES cells for targeted deletion of microRNAs in mice

Haydn M. Prosser, Hiroko Koike-Yusa, James D. Cooper, Frances C. Law, Allan Bradley

Nat Biotechnol. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Nat Biotechnol. 2011 Aug 7; 29(9): 840–845. Published online 2011 Aug 7. doi: 10.1038/nbt.1929

PMCID:: PMC3242032

Abstract Article PDF–2.6M

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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