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Items: 1 to 20 of 230

1.
Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis
Carlos G. Ardanaz, Aida de la Cruz, Paras S. Minhas, Nira Hernández-Martín, Miguel Ángel Pozo, M. Pilar Valdecantos, Ángela M. Valverde, Palmira Villa-Valverde, Marcos Elizalde-Horcada, Elena Puerta, María J. Ramírez, Jorge E. Ortega, Ainhoa Urbiola, Cristina Ederra, Mikel Ariz, Carlos Ortiz-de-Solórzano, Joaquín Fernández-Irigoyen, Enrique Santamaría, Gerard Karsenty, Jens C. Brüning, Maite Solas
Sci Adv. 2024 Oct 18; 10(42): eadp1115. Published online 2024 Oct 18. doi: 10.1126/sciadv.adp1115
PMCID:
PMC11488540
AbstractArticlePDF–1.7M
2.
Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis
Stephen Huang, Casie Reed, Melissa Ilsley, Graham Magor, Michael Tallack, Michael Landsberg, Helen Mitchell, Kevin Gillinder, Andrew Perkins
Nat Commun. 2024; 15: 7019. Published online 2024 Aug 15. doi: 10.1038/s41467-024-50579-4
PMCID:
PMC11327367
AbstractArticlePDF–4.2M
3.
GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism
Kanako Yuki, Mario Vallon, Jie Ding, Cara C. Rada, Alan T. Tang, José G. Vilches-Moure, Aaron K. McCormick, Maria F. Henao Echeverri, Samira Alwahabi, Barbara M. Braunger, Süleyman Ergün, Mark L. Kahn, Calvin J. Kuo
Development. 2024 Jun 1; 151(11): dev202794. Published online 2024 Jun 17. doi: 10.1242/dev.202794
PMCID:
PMC11213517
AbstractArticle
4.
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models
Hoa T.T. Ha, SiYi Liu, Xuan T.A. Nguyen, Linh K. Vo, Nancy C.P. Leong, Dat T. Nguyen, Shivaranjani Balamurugan, Pei Yen Lim, YaJun Wu, Eunju Seong, Toan Q. Nguyen, Jeongah Oh, Markus R. Wenk, Amaury Cazenave-Gassiot, Zuhal Yapici, Wei-Yi Ong, Margit Burmeister, Long N. Nguyen
JCI Insight. 2024 Apr 22; 9(8): e175462. Published online 2024 Mar 7. doi: 10.1172/jci.insight.175462
PMCID:
PMC11141868
AbstractArticlePDF–2.8M
5.
Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance
Jessie E Buth, Catherine E Dyevich, Alexandra Rubin, Chengbing Wang, Lei Gao, Tessa Marks, Michael RM Harrison, Jennifer H Kong, M Elizabeth Ross, Bennett G Novitch, Caroline Alayne Pearson
EMBO Rep. 2024 May; 25(5): 2202–2219. Published online 2024 Apr 10. doi: 10.1038/s44319-024-00131-8
PMCID:
PMC11094073
AbstractArticlePDF–13M
6.
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis
Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina
J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787
PMCID:
PMC11014657
AbstractArticlePDF–16M
7.
SMARCA4 Loss and Mutated β-Catenin Induce Proliferative Lesions in the Murine Embryonic Cerebellum
Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Michael Spohn, Ulrich Schüller
J Neurosci. 2024 Apr 10; 44(15): e1605232024. Prepublished online 2024 Feb 21. doi: 10.1523/JNEUROSCI.1605-23.2024
PMCID:
PMC11007475
AbstractArticlePDF–26M
8.
Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8+ T cell memory development
Stefania D’Aria, Céline Maquet, Shuang Li, Suveera Dhup, Anouk Lepez, Arnaud Kohler, Vincent F. Van Hée, Rajesh K. Dadhich, Marine Frenière, Fabienne Andris, Ivan Nemazanyy, Pierre Sonveaux, Bénédicte Machiels, Laurent Gillet, Michel Y. Braun
Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13): e2306763121. Published online 2024 Mar 18. doi: 10.1073/pnas.2306763121
PMCID:
PMC10990098
AbstractArticlePDF–4.6M
9.
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin
Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan
EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y
PMCID:
PMC10987662
AbstractArticlePDF–12M
10.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
11.
GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing
Dong-Min Yu, Jiawei Zhao, Eunice E. Lee, Dohun Kim, Ruchika Mahapatra, Elysha K. Rose, Zhiwei Zhou, Calvin Hosler, Abdullah El Kurdi, Jun-Yong Choe, E. Dale Abel, Gerta Hoxhaj, Kenneth D. Westover, Raymond J. Cho, Jeffrey B. Cheng, Richard C. Wang
J Clin Invest. 2023 Nov 1; 133(21): e170706. Published online 2023 Nov 1. doi: 10.1172/JCI170706
PMCID:
PMC10617774
AbstractArticlePDF–11M
12.
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Maria Rodriguez-Zabala, Ramprasad Ramakrishnan, Katrin Reinbach, Somadri Ghosh, Leal Oburoglu, Antoni Falqués-Costa, Kishan Bellamkonda, Mats Ehinger, Pablo Peña-Martínez, Noelia Puente-Moncada, Henrik Lilljebjörn, Jörg Cammenga, Cornelis Jan Pronk, Vladimir Lazarevic, Thoas Fioretos, Anna K. Hagström-Andersson, Niels-Bjarne Woods, Marcus Järås
Blood Adv. 2023 Sep 26; 7(18): 5382–5395. Published online 2023 Jul 30. doi: 10.1182/bloodadvances.2023009967
PMCID:
PMC10509671
AbstractArticlePDF–1.4M
13.
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis
Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver
Nat Commun. 2023; 14: 4129. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39672-2
PMCID:
PMC10349100
AbstractArticlePDF–7.7M
14.
miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1
Yinchu Zhan, Chenlin Chen, Zhiqiang Wu, Feng Zhou, Xinping Yu
PeerJ. 2023; 11: e15612. Published online 2023 Jun 30. doi: 10.7717/peerj.15612
PMCID:
PMC10317017
AbstractArticlePDF–13M
15.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
16.
Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice
Jacob J. Aiello, Maislin C. Bogart, Wai-Ting Chan, Nicholas C. Holoman, Timothy D. Trobenter, Chloe E. Relf, Dana M. Kleinman, Darryl C. De Vivo, Ivy S. Samuels
Am J Pathol. 2023 Jul; 193(7): 927–938. doi: 10.1016/j.ajpath.2023.04.003
PMCID:
PMC10294444
AbstractArticlePDF–2.9M
17.
GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc
Shira N. Johnston, Elizabeth S. Silagi, Vedavathi Madhu, Duc H. Nguyen, Irving M. Shapiro, Makarand V. Risbud
JCI Insight. 2023 Apr 24; 8(8): e164883. Published online 2023 Apr 24. doi: 10.1172/jci.insight.164883
PMCID:
PMC10243741
AbstractArticlePDF–17M
18.
Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome
Naeimeh Tayebi, Brian Leon‐Ricardo, Kevin McCall, Elvisa Mehinovic, Kristin Engelstad, Vincent Huynh, Tychele N. Turner, Judy Weisenberg, Liu L. Thio, Paul Hruz, Robin S. B. Williams, Darryl C. De Vivo, Vincent Petit, Gabe Haller, Christina A. Gurnett
Ann Clin Transl Neurol. 2023 May; 10(5): 787–801. Published online 2023 Mar 31. doi: 10.1002/acn3.51767
PMCID:
PMC10187726
AbstractArticlePDF–1.1M
19.
Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice
Charles J. Kim, Chanpreet Singh, Christine Lee, Kevin DiMagno, Madison O'Donnell, Marina Kaczmarek, Arhum Ahmed, Jessica Salvo‐Schaich, Alexis Perez, William Letsou, Maria‐Alicia Carrillo Sepulveda, Raddy L. Ramos, Michael Hadjiargyrou
Physiol Rep. 2023 May; 11(9): e15674. Published online 2023 May 11. doi: 10.14814/phy2.15674
PMCID:
PMC10175242
AbstractArticlePDF–5.3M
20.
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Henrike Janssen, Florian Kahles, Dan Liu, Jeffrey Downey, Laura Koekkoek, Vladimir Roudko, Darwin D’Souza, Cameron S. McAlpine, Lennard Halle, Wolfram C. Poller, Christopher T. Chan, Shun He, John E. Mindur, Mate Kiss, Sumnima Singh, Atsushi Anzai, Yoshiko Iwamoto, Rainer H. Kohler, Kashish Chetal, Ruslan I. Sadreyev, Ralph Weissleder, Seunghee Kim-Schulze, Miriam Merad, Matthias Nahrendorf, Filip K. Swirski
Immunity. Author manuscript; available in PMC 2024 Apr 11.
Published in final edited form as: Immunity. 2023 Apr 11; 56(4): 783–796.e7. Published online 2023 Feb 23. doi: 10.1016/j.immuni.2023.01.024
PMCID:
PMC10101885
AbstractArticlePDF–2.5M

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