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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 101469002.

ZFP750 affects the cutaneous barrier through regulating lipid metabolism

Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino

Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423

PMCID:: PMC10146900

Abstract Article PDF–2.3M

Select item 88033373.

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

Lisa M. Godsel, Quinn R. Roth-Carter, Jennifer L. Koetsier, Lam C. Tsoi, Amber L. Huffine, Joshua A. Broussard, Gillian N. Fitz, Sarah M. Lloyd, Junghun Kweon, Hope E. Burks, Marihan Hegazy, Saki Amagai, Paul W. Harms, Xianying Xing, Joseph Kirma, Jodi L. Johnson, Gloria Urciuoli, Lynn T. Doglio, William R. Swindell, Rajeshwar Awatramani, Eli Sprecher, Xiaomin Bao, Eran Cohen-Barak, Caterina Missero, Johann E. Gudjonsson, Kathleen J. Green

J Clin Invest. 2022 Feb 1; 132(3): e144363. Published online 2022 Feb 1. doi: 10.1172/JCI144363

PMCID:: PMC8803337

Abstract Article PDF–3.6M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 62768355.

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice

Sandra C P De Castro, Peter Gustavsson, Abigail R Marshall, William M Gordon, Gabriel Galea, Evanthia Nikolopoulou, Dawn Savery, Ana Rolo, Philip Stanier, Bogi Andersen, Andrew J Copp, Nicholas D E Greene

Hum Mol Genet. 2018 Dec 15; 27(24): 4218–4230. Published online 2018 Sep 4. doi: 10.1093/hmg/ddy313

PMCID:: PMC6276835

Abstract Article PDF–25M

Select item 59433186.

Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis

Hideki Tatsukawa, Risa Otsu, Yuji Tani, Ryosuke Wakita, Kiyotaka Hitomi

Sci Rep. 2018; 8: 7306. Published online 2018 May 9. doi: 10.1038/s41598-018-25674-4

PMCID:: PMC5943318

Abstract Article PDF–8.6M

Select item 58627717.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 51779488.

ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways

Cristina Wolf , Yawen Qian, Matthew A. Brooke, David P. Kelsell, Claus-Werner Franzke

Sci Rep. 2016; 6: 39780. Published online 2016 Dec 22. doi: 10.1038/srep39780

Correction in:: Sci Rep. 2017; 7: 41343.

PMCID:: PMC5177948

Abstract Article PDF–1.9M

Select item 49560529.

Activation of Molecular Signatures for Antimicrobial and Innate Defense Responses in Skin with Transglutaminase 1 Deficiency

Takashi Haneda, Yasutomo Imai, Ryosuke Uchiyama, Orie Jitsukawa, Kiyofumi Yamanishi

PLoS One. 2016; 11(7): e0159673. Published online 2016 Jul 21. doi: 10.1371/journal.pone.0159673

PMCID:: PMC4956052

Abstract Article PDF–2.2M

Select item 493131910.

IL-13 from intraepithelial lymphocytes regulates tissue homeostasis and protects against carcinogenesis in the skin

Tim Dalessandri, Greg Crawford, Mark Hayes, Rocio Castro Seoane, Jessica Strid

Nat Commun. 2016; 7: 12080. Published online 2016 Jun 30. doi: 10.1038/ncomms12080

PMCID:: PMC4931319

Abstract Article PDF–854K

Select item 431955911.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 380857612.

Variations in Both TG1 and TG2 Isozyme-specific In Situ Activities and Protein Expressions during Mouse Embryonic Development

Miho Itoh, Hideki Tatsukawa, Lee Eun-Seo, Kiyofumi Yamanishi, Soichi Kojima, Kiyotaka Hitomi

J Histochem Cytochem. 2013 Nov; 61(11): 793–801. doi: 10.1369/0022155413501676

PMCID:: PMC3808576

Abstract Article PDF–1.2M

Select item 344481613.

Transglutaminase Inhibition Protects against Oxidative Stress-Induced Neuronal Death Downstream of Pathological ERK Activation

Manuela Basso, Jill Berlin, Li Xia, Sama F. Sleiman, Brendan Ko, Renee Haskew-Layton, Eunhee Kim, Marc A. Antonyak, Richard A. Cerione, Siiri E. Iismaa, Dianna Willis, Sunghee Cho, Rajiv R. Ratan

J Neurosci. 2012 May 9; 32(19): 6561–6569. doi: 10.1523/JNEUROSCI.3353-11.2012

Correction in:: J Neurosci. 2012 Aug 8; 32(32): 11157.

PMCID:: PMC3444816

Abstract Article PDF–1.3M

Select item 333079514.

Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2

Kyle B. Johnson, Humphrey Petersen-Jones, Janice M. Thompson, Kiyotaka Hitomi, Miho Itoh, Erik N. T. P. Bakker, Gail V. W. Johnson, Gozde Colak, Stephanie W. Watts

Am J Physiol Heart Circ Physiol. 2012 Apr 1; 302(7): H1355–H1366. Published online 2012 Feb 3. doi: 10.1152/ajpheart.00918.2011

PMCID:: PMC3330795

Abstract Article

Select item 320113215.

In Situ Detection of Active Transglutaminases for Keratinocyte Type (TGase 1) and Tissue Type (TGase 2) Using Fluorescence-Labeled Highly Reactive Substrate Peptides

Miho Itoh, Tadafumi Kawamoto, Hideki Tatsukawa, Soichi Kojima, Kiyofumi Yamanishi, Kiyotaka Hitomi

J Histochem Cytochem. 2011 Feb; 59(2): 180–187. doi: 10.1369/jhc.2010.957225

PMCID:: PMC3201132

Abstract Article PDF–460K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 275472218.

Dual Role of COUP-TF-Interacting Protein 2 in Epidermal Homeostasis and Permeability Barrier Formation

Olga Golonzhka, Xiaobo Liang, Nadia Messaddeq, Jean-Marc Bornert, Adam L. Campbell, Daniel Metzger, Pierre Chambon, Gitali Ganguli-Indra, Mark Leid, Arup K. Indra

J Invest Dermatol. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: J Invest Dermatol. 2009 Jun; 129(6): 1459–1470. Published online 2008 Dec 18. doi: 10.1038/jid.2008.392

PMCID:: PMC2754722

Abstract Article PDF–4.2M

Select item 263194619.

Transglutaminase-1 Regulates Renal Epithelial Cell Proliferation through Activation of Stat-3

Zhu Zhang, Jingping Xing, Li Ma, Rujun Gong, Y. Eugene Chin, Shougang Zhuang

J Biol Chem. 2009 Jan 30; 284(5): 3345–3353. doi: 10.1074/jbc.M808396200

PMCID:: PMC2631946

Abstract Article PDF–623K

Select item 255704020.

AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis

Xuan Wang, H. Amalia Pasolli, Trevor Williams, Elaine Fuchs

J Cell Biol. 2008 Oct 6; 183(1): 37–48. doi: 10.1083/jcb.200804030

PMCID:: PMC2557040

Abstract Article PDF–4.7M

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