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Select item 104935881.

Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2

Satoru Torii, Satoko Arakawa, Shigeto Sato, Kei‐ichi Ishikawa, Daisuke Taniguchi, Hajime Tajima Sakurai, Shinya Honda, Yuuichi Hiraoka, Masaya Ono, Wado Akamatsu, Nobutaka Hattori, Shigeomi Shimizu

EMBO Mol Med. 2023 Sep; 15(9): e17451. Published online 2023 Aug 14. doi: 10.15252/emmm.202317451

PMCID:: PMC10493588

Abstract Article PDF–13M

Select item 104650012.

In vivo recording of suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in circadian pacesetting

Yusuke Tsuno, Yubo Peng, Shin-ichi Horike, Mohan Wang, Ayako Matsui, Kanato Yamagata, Mizuki Sugiyama, Takahiro J. Nakamura, Takiko Daikoku, Takashi Maejima, Michihiro Mieda

PLoS Biol. 2023 Aug; 21(8): e3002281. Published online 2023 Aug 29. doi: 10.1371/journal.pbio.3002281

PMCID:: PMC10465001

Abstract Article PDF–5.5M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 80179604.

GABA from vasopressin neurons regulates the time at which suprachiasmatic nucleus molecular clocks enable circadian behavior

Takashi Maejima, Yusuke Tsuno, Shota Miyazaki, Yousuke Tsuneoka, Emi Hasegawa, Md Tarikul Islam, Ryosuke Enoki, Takahiro J. Nakamura, Michihiro Mieda

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2010168118. Published online 2021 Feb 1. doi: 10.1073/pnas.2010168118

PMCID:: PMC8017960

Abstract Article PDF–5.3M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77146936.

CK1δ over-expressing mice display ADHD-like behaviors, frontostriatal neuronal abnormalities and altered expressions of ADHD-candidate genes

Mingming Zhou, Jodi Gresack, Jia Cheng, Kunihiro Uryu, Lars Brichta, Paul Greengard, Marc Flajolet

Mol Psychiatry. 2020; 25(12): 3322–3336. Published online 2018 Oct 19. doi: 10.1038/s41380-018-0233-z

PMCID:: PMC7714693

Abstract Article PDF–2.6M

Select item 72950337.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 72451258.

Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch

Shusaku Masuda, Rajesh Narasimamurthy, Hikari Yoshitane, Jae Kyoung Kim, Yoshitaka Fukada, David M. Virshup

Proc Natl Acad Sci U S A. 2020 May 19; 117(20): 10888–10896. Published online 2020 Apr 30. doi: 10.1073/pnas.2000266117

PMCID:: PMC7245125

Abstract Article PDF–1.4M

Select item 72251299.

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk

SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens

Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369

PMCID:: PMC7225129

Abstract Article

Select item 700734310.

Auto-kinase activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms

Gaili Guo, Kankan Wang, Shan-Shan Hu, Tian Tian, Peng Liu, Tetsuya Mori, Peng Chen, Carl Hirschie Johnson, Ximing Qin

J Biol Rhythms. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: J Biol Rhythms. 2019 Oct; 34(5): 482–496. Published online 2019 Aug 8. doi: 10.1177/0748730419865406

PMCID:: PMC7007343

Abstract Article PDF–1.7M

Select item 672542211.

Physiological Role for Casein Kinase 1 in Glutamatergic Synaptic Transmission

Karima Chergui, Per Svenningsson, Paul Greengard

J Neurosci. 2005 Jul 13; 25(28): 6601–6609. doi: 10.1523/JNEUROSCI.1082-05.2005

PMCID:: PMC6725422

Abstract Article PDF–679K

Select item 600337912.

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

Rajesh Narasimamurthy, Sabrina R. Hunt, Yining Lu, Jean-Michel Fustin, Hitoshi Okamura, Carrie L. Partch, Daniel B. Forger, Jae Kyoung Kim, David M. Virshup

Proc Natl Acad Sci U S A. 2018 Jun 5; 115(23): 5986–5991. Published online 2018 May 21. doi: 10.1073/pnas.1721076115

PMCID:: PMC6003379

Abstract Article PDF–1.0M

Select item 600337313.

Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock

Jean-Michel Fustin, Rika Kojima, Kakeru Itoh, Hsin-Yi Chang, Shiqi Ye, Bowen Zhuang, Asami Oji, Shingo Gibo, Rajesh Narasimamurthy, David Virshup, Gen Kurosawa, Masao Doi, Ichiro Manabe, Yasushi Ishihama, Masahito Ikawa, Hitoshi Okamura

Proc Natl Acad Sci U S A. 2018 Jun 5; 115(23): 5980–5985. Published online 2018 May 21. doi: 10.1073/pnas.1721371115

Correction in:: Proc Natl Acad Sci U S A. 2018 Jul 3; 115(27): E6386.

PMCID:: PMC6003373

Abstract Article PDF–1.2M

Select item 587798914.

Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes

Vincent van der Vinne, Steven J. Swoap, Thomas J. Vajtay, David R. Weaver

Proc Natl Acad Sci U S A. 2018 Mar 6; 115(10): E2437–E2446. Published online 2018 Feb 20. doi: 10.1073/pnas.1712324115

PMCID:: PMC5877989

Abstract Article PDF–2.3M

Select item 577725815.

Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions

Kyung Ho Lee, Jeong-Ah Hwang, Sun-Ok Kim, Jung Hee Kim, Sang Chul Shin, Eunice EunKyeong Kim, Kyung S. Lee, Kunsoo Rhee, Byeong Hwa Jeon, Jeong Kyu Bang, Hyunjoo Cha-Molstad, Nak-Kyun Soung, Jae-Hyuk Jang, Sung-Kyun Ko, Hee Gu Lee, Jong Seog Ahn, Yong Tae Kwon, Bo Yeon Kim

J Biol Chem. 2018 Jan 19; 293(3): 847–862. Published online 2017 Nov 30. doi: 10.1074/jbc.M117.802587

PMCID:: PMC5777258

Abstract Article PDF–4.4M

Select item 571740316.

Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development

Wei Yang, Lisa Garrett, Di Feng, Gene Elliott, Xilin Liu, Ni Wang, Yu Ming Wong, Nga Ting Choi, Yingzi Yang, Bo Gao

Cell Res. 2017 Dec; 27(12): 1466–1484. Published online 2017 Oct 20. doi: 10.1038/cr.2017.127

PMCID:: PMC5717403

Abstract Article PDF–12M

Select item 568788617.

ESRP1 mutations cause hearing loss due to defects in alternative splicing that disrupt cochlear development

Alex M. Rohacek, Thomas W. Bebee, Richard K. Tilton, Caleb M. Radens, Chris McDermott-Roe, Natoya Peart, Maninder Kaur, Michael Zaykaner, Benjamin Cieply, Kiran Musunuru, Yoseph Barash, John A. Germiller, Ian D. Krantz, Russ P. Carstens, Douglas J. Epstein

Dev Cell. Author manuscript; available in PMC 2018 Nov 6.

Published in final edited form as: Dev Cell. 2017 Nov 6; 43(3): 318–331.e5. Published online 2017 Oct 26. doi: 10.1016/j.devcel.2017.09.026

PMCID:: PMC5687886

Abstract Article PDF–2.4M

Select item 565674718.

USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination

Laura Novellasdemunt, Valentina Foglizzo, Laura Cuadrado, Pedro Antas, Anna Kucharska, Vesela Encheva, Ambrosius P. Snijders, Vivian S.W. Li

Cell Rep. 2017 Oct 17; 21(3): 612–627. Published online 2017 Oct 17. doi: 10.1016/j.celrep.2017.09.072

PMCID:: PMC5656747

Abstract Article PDF–5.1M

Select item 564190419.

Casein kinase 1‐epsilon or 1‐delta required for Wnt‐mediated intestinal stem cell maintenance

Yael Morgenstern, Upasana Das Adhikari, Muneef Ayyash, Ela Elyada, Beáta Tóth, Andreas Moor, Shalev Itzkovitz, Yinon Ben‐Neriah

EMBO J. 2017 Oct 16; 36(20): 3046–3061. Published online 2017 Sep 28. doi: 10.15252/embj.201696253

PMCID:: PMC5641904

Abstract Article PDF–2.1M

Select item 526848120.

Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1

Yoshimi Endo Greer, Bo Gao, Yingzi Yang, Andre Nussenzweig, Jeffrey S. Rubin

PLoS One. 2017; 12(1): e0170903. Published online 2017 Jan 26. doi: 10.1371/journal.pone.0170903

PMCID:: PMC5268481

Abstract Article PDF–2.4M

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