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Items: 1 to 20 of 44

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Nr6a1 controls Hox expression dynamics and is a master regulator of vertebrate trunk development
Yi-Cheng Chang, Jan Manent, Jan Schroeder, Siew Fen Lisa Wong, Gabriel M. Hauswirth, Natalia A. Shylo, Emma L. Moore, Annita Achilleos, Victoria Garside, Jose M. Polo, Paul Trainor, Edwina McGlinn
Nat Commun. 2022; 13: 7766. Published online 2022 Dec 15. doi: 10.1038/s41467-022-35303-4
PMCID:
PMC9755267
AbstractArticlePDF–2.9M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
Suppression of Oct4 by Germ Cell Nuclear Factor Restricts Pluripotency and Promotes Neural Stem Cell Development in the Early Neural Lineage
Wado Akamatsu, Brian DeVeale, Hideyuki Okano, Austin J Cooney, Derek van der Kooy
J Neurosci. 2009 Feb 18; 29(7): 2113–2124. doi: 10.1523/JNEUROSCI.4527-08.2009
PMCID:
PMC6666351
AbstractArticlePDF–18M
5.
USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta
Evangelia Koutelou, Li Wang, Andria C. Schibler, Hsueh-Ping Chao, Xianghong Kuang, Kevin Lin, Yue Lu, Jianjun Shen, Collene R. Jeter, Andrew Salinger, Marenda Wilson, Yi Chun Chen, Boyko S. Atanassov, Dean G. Tang, Sharon Y. R. Dent
Development. 2019 Feb 15; 146(4): dev174037. Published online 2019 Feb 22. doi: 10.1242/dev.174037
PMCID:
PMC6398448
AbstractArticle
6.
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay
Nat Commun. 2018; 9: 5321. Published online 2018 Dec 14. doi: 10.1038/s41467-018-07786-7
PMCID:
PMC6294001
AbstractArticlePDF–859K
7.
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF) and Liver Receptor Homolog-1 (LRH-1)
Emily R. Weikum, Micheal L. Tuntland, Michael N. Murphy, Eric A. Ortlund
J Mol Biol. Author manuscript; available in PMC 2017 Dec 4.
Published in final edited form as: J Mol Biol. 2016 Dec 4; 428(24 Pt B): 4981–4992. Published online 2016 Oct 27. doi: 10.1016/j.jmb.2016.10.025
PMCID:
PMC5362318
AbstractArticlePDF–1.6M
8.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
9.
Abnormal Labyrinthine Zone in the Hectd1-null Placenta
Anjali A. Sarkar, Julia A. Sabatino, Kelsey F. Sugrue, Irene E. Zohn
Placenta. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Placenta. 2016 Feb; 38: 16–23. Published online 2015 Dec 13. doi: 10.1016/j.placenta.2015.12.002
PMCID:
PMC4768308
AbstractArticlePDF–3.6M
10.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
11.
Germ Cell Nuclear Factor Regulates Gametogenesis in Developing Gonads
Davood Sabour, Xueping Xu, Arthur C. K. Chung, Damien Le Menuet, Kinarm Ko, Natalia Tapia, Marcos J. Araúzo-Bravo, Luca Gentile, Boris Greber, Karin Hübner, Vittorio Sebastiano, Guangming Wu, Hans R. Schöler, Austin J. Cooney
PLoS One. 2014; 9(8): e103985. Published online 2014 Aug 20. doi: 10.1371/journal.pone.0103985
PMCID:
PMC4139263
AbstractArticlePDF–1.9M
12.
GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ES cell differentiation
Hongran Wang, Xiaohong Wang, Trevor K. Archer, Thomas P. Zwaka, Austin J. Cooney
Stem Cells. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Stem Cells. 2014 Jun; 32(6): 1527–1537. doi: 10.1002/stem.1689
PMCID:
PMC4091926
AbstractArticlePDF–1.9M
13.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
14.
A chronological expression profile of gene activity during embryonic mouse brain development
P. Goggolidou, S. Soneji, N. Powles-Glover, D. Williams, S. Sethi, D. Baban, M. M. Simon, I. Ragoussis, D. P. Norris
Mamm Genome. 2013; 24(11): 459–472. Published online 2013 Nov 19. doi: 10.1007/s00335-013-9486-7
PMCID:
PMC3843766
AbstractArticlePDF–624K
15.
The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells
Leah M. Okumura, Bluma J. Lesch, David C. Page
PLoS One. 2013; 8(6): e66062. Published online 2013 Jun 7. doi: 10.1371/journal.pone.0066062
PMCID:
PMC3676325
AbstractArticlePDF–7.1M
16.
Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts
Allan M. Gurtan, Arvind Ravi, Peter B. Rahl, Andrew D. Bosson, Courtney K. JnBaptiste, Arjun Bhutkar, Charles A. Whittaker, Richard A. Young, Phillip A. Sharp
Genes Dev. 2013 Apr 15; 27(8): 941–954. doi: 10.1101/gad.215376.113
PMCID:
PMC3650230
AbstractArticlePDF–1.9M
17.
Dicer Deficiency Reveals MicroRNAs Predicted to Control Gene Expression in the Developing Adrenal Cortex
Kenneth T. Krill, Katherine Gurdziel, Joanne H. Heaton, Derek P. Simon, Gary D. Hammer
Mol Endocrinol. 2013 May; 27(5): 754–768. Published online 2013 Mar 21. doi: 10.1210/me.2012-1331
PMCID:
PMC3634112
AbstractArticle
18.
The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice
Judith Reichmann, James P. Reddington, Diana Best, David Read, Rupert Öllinger, Richard R. Meehan, Ian R. Adams
Hum Mol Genet. 2013 May 1; 22(9): 1791–1806. Published online 2013 Jan 30. doi: 10.1093/hmg/ddt029
PMCID:
PMC3613164
AbstractArticlePDF–1.4M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Differential Recruitment of Methyl CpG-Binding Domain Factors and DNA Methyltransferases by the Orphan Receptor Germ Cell Nuclear Factor Initiates the Repression and Silencing of Oct4
Peili Gu, Xueping Xu, Damien Le Menuet, Arthur C-K Chung, Austin J Cooney
Stem Cells. 2011 Jul; 29(7): 1041–1051. Published online 2011 May 23. doi: 10.1002/stem.652
PMCID:
PMC3468724
AbstractArticlePDF–2.7M

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