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Select item 112024561.

Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin’s Protective Mechanisms in Experimental Bronchopulmonary Dysplasia

Subarna Palit, Amrit Kumar Shrestha, Shyam Thapa, Sandra L. Grimm, Cristian Coarfa, Fabian Theis, Lukas M. Simon, Binoy Shivanna

Genes (Basel) 2024 Jun; 15(6): 806. Published online 2024 Jun 19. doi: 10.3390/genes15060806

PMCID:: PMC11202456

Abstract Article PDF–4.5M

Select item 106243512.

Adrenomedullin has a pivotal role in trophoblast differentiation: A promising nanotechnology-based therapeutic target for early-onset preeclampsia

Qingqing Zhang, Cheuk-Lun Lee, Tingyu Yang, Jianlin Li, Qunxiong Zeng, Xiaofeng Liu, Zhongzhen Liu, Degong Ruan, Zhuoxuan Li, Anita S. Y. Kan, Ka-Wang Cheung, Annisa S. L. Mak, Vivian W. Y. Ng, Huashan Zhao, Xiujun Fan, Yong-Gang Duan, Liuying Zhong, Min Chen, Meirong Du, Raymond H. W. Li, Pengtao Liu, Ernest H. Y. Ng, William S. B. Yeung, Ya Gao, Yuanqing Yao, Philip C. N. Chiu

Sci Adv. 2023 Nov 3; 9(44): eadi4777. Published online 2023 Nov 3. doi: 10.1126/sciadv.adi4777

PMCID:: PMC10624351

Abstract Article PDF–3.2M

Select item 97948243.

Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng, Abha Bais, Haoting He, Cassandra Rios, Shan Jiang, Juan Xu, Cindy Chang, Dennis Kostka, Guang Li

Nat Commun. 2022; 13: 7960. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35691-7

PMCID:: PMC9794824

Abstract Article PDF–17M

Select item 96659024.

Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth

Akiko Nakayama, Kenneth Anthony Roquid, András Iring, Boris Strilic, Stefan Günther, Min Chen, Lee S. Weinstein, Stefan Offermanns

J Exp Med. 2023 Jan 2; 220(1): e20211628. Published online 2022 Nov 14. doi: 10.1084/jem.20211628

PMCID:: PMC9665902

Abstract Article PDF–8.1M

Select item 89950875.

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac

Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson

Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131

PMCID:: PMC8995087

Abstract Article

Select item 86474316.

Adrenomedullin Deficiency Potentiates Lipopolysaccharide-Induced Experimental Bronchopulmonary Dysplasia in Neonatal Mice

Amrit K. Shrestha, Renuka T. Menon, Chandrasekhar Yallampalli, Roberto Barrios, Binoy Shivanna

Am J Pathol. 2021 Dec; 191(12): 2080–2090. doi: 10.1016/j.ajpath.2021.09.001

PMCID:: PMC8647431

Abstract Article PDF–3.0M

Select item 85602117.

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

Siyeon Rhee, David T Paik, Johnson Y Yang, Danielle Nagelberg, Ian Williams, Lei Tian, Robert Roth, Mark Chandy, Jiyeon Ban, Nadjet Belbachir, Seokho Kim, Hao Zhang, Ragini Phansalkar, Ka Man Wong, Devin A King, Caroline Valdez, Virginia D Winn, Ashby J Morrison, Joseph C Wu, Kristy Red-Horse

Eur Heart J. 2021 Nov 1; 42(41): 4264–4276. Published online 2021 Jul 19. doi: 10.1093/eurheartj/ehab298

PMCID:: PMC8560211

Abstract Article PDF–1.8M

Select item 79502888.

Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway

Xian-Qiang Ni, Ya-Rong Zhang, Li-Xin Jia, Wei-Wei Lu, Qing Zhu, Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Xin Liu, Yan-Rong Yu, Mo-Zhi Jia, Zhong-Ping Ning, Jie Du, Chao-Shu Tang, Yong-Fen Qi

Aging (Albany NY) 2021 Feb 28; 13(4): 5164–5184. Published online 2021 Feb 1. doi: 10.18632/aging.202436

PMCID:: PMC7950288

Abstract Article PDF–2.4M

Select item 77144049.

Disturbed flow–induced G_s-mediated signaling protects against endothelial inflammation and atherosclerosis

Akiko Nakayama, Julián Albarrán-Juárez, Guozheng Liang, Kenneth Anthony Roquid, András Iring, Sarah Tonack, Min Chen, Oliver J. Müller, Lee S. Weinstein, Stefan Offermanns

JCI Insight. 2020 Dec 3; 5(23): e140485. Published online 2020 Dec 3. doi: 10.1172/jci.insight.140485

PMCID:: PMC7714404

Abstract Article PDF–42M

Select item 751566910.

Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta

Laurent Yvernogeau, Anna Klaus, Joris Maas, Ismaël Morin-Poulard, Bart Weijts, Stefan Schulte-Merker, Eugene Berezikov, Jan Philipp Junker, Catherine Robin

Blood. 2020 Aug 13; 136(7): 831–844. Prepublished online 2020 May 26. doi: 10.1182/blood.2019004446

PMCID:: PMC7515669

Abstract Article

Select item 707434311.

Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice

Renuka T. Menon, Amrit Kumar Shrestha, Corey L. Reynolds, Roberto Barrios, Kathleen M. Caron, Binoy Shivanna

Am J Pathol. 2020 Mar; 190(3): 711–722. doi: 10.1016/j.ajpath.2019.11.011

PMCID:: PMC7074343

Abstract Article PDF–3.4M

Select item 665555112.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 659723213.

Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

Andras Iring, Young-June Jin, Julián Albarrán-Juárez, Mauro Siragusa, ShengPeng Wang, Péter T. Dancs, Akiko Nakayama, Sarah Tonack, Min Chen, Carsten Künne, Anna M. Sokol, Stefan Günther, Alfredo Martínez, Ingrid Fleming, Nina Wettschureck, Johannes Graumann, Lee S. Weinstein, Stefan Offermanns

J Clin Invest. 2019 Jul 1; 129(7): 2775–2791. Published online 2019 Jun 17. doi: 10.1172/JCI123825

PMCID:: PMC6597232

Abstract Article PDF–8.8M

Select item 639844814.

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

Evangelia Koutelou, Li Wang, Andria C. Schibler, Hsueh-Ping Chao, Xianghong Kuang, Kevin Lin, Yue Lu, Jianjun Shen, Collene R. Jeter, Andrew Salinger, Marenda Wilson, Yi Chun Chen, Boyko S. Atanassov, Dean G. Tang, Sharon Y. R. Dent

Development. 2019 Feb 15; 146(4): dev174037. Published online 2019 Feb 22. doi: 10.1242/dev.174037

PMCID:: PMC6398448

Abstract Article

Select item 636246115.

Genetic loss of proadrenomedullin N-terminal 20 peptide (PAMP) in mice is compatible with survival

Brooke C. Matson, Manyu Li, Claire E. Trincot, Elizabeth S. Blakeney, Stephanie L. Pierce, Kathleen M. Caron

Peptides. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Peptides. 2019 Feb; 112: 96–100. Published online 2018 Dec 8. doi: 10.1016/j.peptides.2018.11.005

PMCID:: PMC6362461

Abstract Article PDF–491K

Select item 631806316.

Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Cx43

Claire E. Trincot, Wenjing Xu, Hua Zhang, Molly R. Kulikauskas, Thomas G. Caranasos, Brian C. Jensen, Amelie Sabine, Tatiana V. Petrova, Kathleen M. Caron

Circ Res. Author manuscript; available in PMC 2020 Jan 4.

Published in final edited form as: Circ Res. 2019 Jan 4; 124(1): 101–113. doi: 10.1161/CIRCRESAHA.118.313835

PMCID:: PMC6318063

Abstract Article PDF–1.4M

Select item 624847617.

Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium

Brooke C Matson, Stephanie L Pierce, Scott T Espenschied, Eric Holle, Imani H Sweatt, Eric S Davis, Robert Tarran, Steven L Young, Trudy A Kohout, Marcel van Duin, Kathleen M Caron

Biol Reprod. 2017 Sep; 97(3): 466–477. Published online 2017 Aug 28. doi: 10.1093/biolre/iox101

PMCID:: PMC6248476

Abstract Article PDF–7.1M

Select item 614051018.

Precursor proadrenomedullin influences cardiomyocyte survival and local inflammation related to myocardial infarction

Svenja Hinrichs, Katharina Scherschel, Saskia Krüger, Johannes Tobias Neumann, Michael Schwarzl, Isabell Yan, Svenja Warnke, Francisco M. Ojeda, Tanja Zeller, Mahir Karakas, Till Keller, Christian Meyer, Stefan Blankenberg, Dirk Westermann, Diana Lindner

Proc Natl Acad Sci U S A. 2018 Sep 11; 115(37): E8727–E8736. Published online 2018 Aug 30. doi: 10.1073/pnas.1721635115

PMCID:: PMC6140510

Abstract Article PDF–2.0M

Select item 607483319.

Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes

Shraddha Sharma, Jianming Wang, Eduardo Cortes Gomez, Robert T. Taggart, Bora E. Baysal

Hum Mol Genet. 2017 Apr 1; 26(7): 1328–1339. Published online 2017 Feb 13. doi: 10.1093/hmg/ddx041

PMCID:: PMC6074833

Abstract Article PDF–810K

Select item 602596820.

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment

Leona Matsumoto, Yasushi Hirota, Tomoko Saito-Fujita, Norihiko Takeda, Tomoki Tanaka, Takehiro Hiraoka, Shun Akaeda, Hidetoshi Fujita, Ryoko Shimizu-Hirota, Shota Igaue, Mitsunori Matsuo, Hirofumi Haraguchi, Mayuko Saito-Kanatani, Tomoyuki Fujii, Yutaka Osuga

J Clin Invest. 2018 Jul 2; 128(7): 3186–3197. Published online 2018 Jun 18. doi: 10.1172/JCI98931

PMCID:: PMC6025968

Abstract Article PDF–18M

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