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Select item 113102831.

Single‐cell sequencing combined with spatial transcriptomics reveals that the IRF7 gene in M1 macrophages inhibits the occurrence of pancreatic cancer by regulating lipid metabolism‐related mechanisms

Ting Zhan, Yanli Zou, Zheng Han, XiaoRong Tian, Mengge Chen, Jiaxi Liu, Xiulin Yang, Qingxi Zhu, Meng Liu, Wei Chen, Mingtao Chen, Xiaodong Huang, Jie Tan, Weijie Liu, Xia Tian

Clin Transl Med. 2024 Aug; 14(8): e1799. Published online 2024 Aug 8. doi: 10.1002/ctm2.1799

PMCID:: PMC11310283

Abstract Article PDF–15M

Select item 110401272.

Non-transcriptional IRF7 interacts with NF-κB to inhibit viral inflammation

Shumin Fan, Sonam Popli, Sukanya Chakravarty, Ritu Chakravarti, Saurabh Chattopadhyay

J Biol Chem. 2024 Apr; 300(4): 107200. Published online 2024 Mar 18. doi: 10.1016/j.jbc.2024.107200

PMCID:: PMC11040127

Abstract Article PDF–3.2M

Select item 104496493.

IRF7: role and regulation in immunity and autoimmunity

Wei Ma, Gang Huang, Zhi Wang, Li Wang, Qiangguo Gao

Front Immunol. 2023; 14: 1236923. Published online 2023 Aug 10. doi: 10.3389/fimmu.2023.1236923

PMCID:: PMC10449649

Abstract Article PDF–2.4M

Select item 102696004.

Enterovirus D68 VP3 Targets the Interferon Regulatory Factor 7 To Inhibit Type I Interferon Response

Jun Kang, Mengqian Huang, Jinyu Li, Keke Zhang, Cheng Zhu, Sihua Liu, Zhenwei Zhou, Tao Wang, Zhiyun Wang

Microbiol Spectr. 2023 May-Jun; 11(3): e04138-22. Published online 2023 May 1. doi: 10.1128/spectrum.04138-22

PMCID:: PMC10269600

Abstract Article PDF–3.3M

Select item 102132165.

Interferon regulatory factor 7 in inflammation, cancer and infection

Furong Qing, Zhiping Liu

Front Immunol. 2023; 14: 1190841. Published online 2023 May 12. doi: 10.3389/fimmu.2023.1190841

PMCID:: PMC10213216

Abstract Article PDF–1.8M

Select item 83637316.

Role of interferon regulatory factor 7 in corneal endothelial cells after HSV-1 infection

Fumie Ohtani, Dai Miyazaki, Yumiko Shimizu, Tomoko Haruki, Satoru Yamagami, Yoshitsugu Inoue

Sci Rep. 2021; 11: 16487. Published online 2021 Aug 13. doi: 10.1038/s41598-021-95823-9

PMCID:: PMC8363731

Abstract Article PDF–3.5M

Select item 81725667.

IKKε isoform switching governs the immune response against EV71 infection

Ya-Ling Chang, Yu-Wen Liao, Min-Hsuan Chen, Sui-Yuan Chang, Yao-Ting Huang, Bing-Ching Ho, Sung-Liang Yu

Commun Biol. 2021; 4: 663. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02187-x

PMCID:: PMC8172566

Abstract Article PDF–3.5M

Select item 80090488.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 78410099.

Overexpression of Interferon Regulatory Factor 7 (IRF7) Reduces Bone Metastasis of Prostate Cancer Cells in Mice

Yang Zhao, Wenxia Chen, Weiliang Zhu, Hui Meng, Jie Chen, Jian Zhang

Oncol Res. 2017; 25(4): 511–522. Published online 2017 Apr 14. doi: 10.3727/096504016X14756226781802

PMCID:: PMC7841009

Abstract Article PDF–44M

Select item 783439010.

Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19)

Carolina Scagnolari, Alessandra Pierangeli, Federica Frasca, Camilla Bitossi, Agnese Viscido, Giuseppe Oliveto, Mirko Scordio, Laura Mazzuti, Daniele Di Carlo, Massimo Gentile, Angelo Solimini, Giancarlo Ceccarelli, Francesco Pugliese, Claudio Maria Mastroianni, Gabriella d’Ettorre, Ombretta Turriziani, Guido Antonelli, , on behalf of Virology and Infectious Diseases COVID-19 Study Group of Sapienza University

Virus Res. 2021 Apr 2; 295: 198283. Published online 2021 Jan 5. doi: 10.1016/j.virusres.2020.198283

PMCID:: PMC7834390

Abstract Article PDF–410K

Select item 767247311.

Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization

Louise Dalskov, Ryo Narita, Line L Andersen, Nanna Jensen, Sonia Assil, Kennith H Kristensen, Jacob G Mikkelsen, Takashi Fujita, Trine H Mogensen, Søren R Paludan, Rune Hartmann

Nucleic Acids Res. 2020 Nov 18; 48(20): 11421–11433. Published online 2020 Oct 22. doi: 10.1093/nar/gkaa873

PMCID:: PMC7672473

Abstract Article PDF–3.5M

Select item 748251112.

Infection with herpes simplex type 1-based amplicon vectors results in an IRF3/7-dependent, TLR-independent activation of the innate antiviral response in primary human fibroblasts

Eliza Tsitoura, Joëlle Thomas, Delphine Cuchet, Karine Thoinet, Penelope Mavromara, Alberto L. Epstein

J Gen Virol. 2009 Sep; 90(Pt 9): 2209–2220. doi: 10.1099/vir.0.012203-0

PMCID:: PMC7482511

Abstract Article PDF–659K

Select item 746204913.

A Quantitative Genetic Interaction Map of HIV Infection

David E. Gordon, Ariane Watson, Assen Roguev, Simin Zheng, Gwendolyn M. Jang, Joshua Kane, Jiewei Xu, Jeffrey Z. Guo, Erica Stevenson, Danielle L. Swaney, Kathy Franks-Skiba, Erik Verschueren, Michael Shales, David C. Crosby, Alan D. Frankel, Alexander Marson, Ivan Marazzi, Gerard Cagney, Nevan J. Krogan

Mol Cell. Author manuscript; available in PMC 2021 Apr 16.

Published in final edited form as: Mol Cell. 2020 Apr 16; 78(2): 197–209.e7. Published online 2020 Feb 20. doi: 10.1016/j.molcel.2020.02.004

PMCID:: PMC7462049

Abstract Article PDF–2.4M

Select item 740626414.

RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism

Laura Senatus, Raquel López-Díez, Lander Egaña-Gorroño, Jianhua Liu, Jiyuan Hu, Gurdip Daffu, Qing Li, Karishma Rahman, Yuliya Vengrenyuk, Tessa J. Barrett, M. Zahidunnabi Dewan, Liang Guo, Daniela Fuller, Aloke V. Finn, Renu Virmani, Huilin Li, Richard A. Friedman, Edward A. Fisher, Ravichandran Ramasamy, Ann Marie Schmidt

JCI Insight. 2020 Jul 9; 5(13): e137289. Published online 2020 Jul 9. doi: 10.1172/jci.insight.137289

PMCID:: PMC7406264

Abstract Article PDF–37M

Select item 732206715.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 696167916.

Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathway

Daokun Yang, Xinwei Wang, Haili Gao, Baoxin Chen, Changyun Si, Shasha Wang

Cell Cycle. 2020; 19(2): 179–192. Published online 2019 Dec 19. doi: 10.1080/15384101.2019.1704512

PMCID:: PMC6961679

Abstract Article PDF–6.2M

Select item 649653017.

microRNA‐762 promotes breast cancer cell proliferation and invasion by targeting IRF7 expression

Yongping Li, Ruixue Huang, Ling Wang, Junsheng Hao, Qiong Zhang, Rui Ling, Jun Yun

Cell Prolif. 2015 Dec; 48(6): 643–649. Published online 2015 Nov 2. doi: 10.1111/cpr.12223

PMCID:: PMC6496530

Abstract Article PDF–953K

Select item 648013118.

The Eukaryotic Translation Initiation Factor 4F Complex Restricts Rotavirus Infection via Regulating the Expression of IRF1 and IRF7

Sunrui Chen, Cui Feng, Yan Fang, Xinying Zhou, Lei Xu, Wenshi Wang, Xiangdong Kong, Maikel P. Peppelenbosch, Qiuwei Pan, Yuebang Yin

Int J Mol Sci. 2019 Apr; 20(7): 1580. Published online 2019 Mar 29. doi: 10.3390/ijms20071580

PMCID:: PMC6480131

Abstract Article PDF–2.2M

Select item 647789119.

Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer

Qiang Lan, Sanam Peyvandi, Nathalie Duffey, Yu-Ting Huang, David Barras, Werner Held, François Richard, Mauro Delorenzi, Christos Sotiriou, Christine Desmedt, Girieca Lorusso, Curzio Rüegg

Oncogene. 2019; 38(15): 2814–2829. Published online 2018 Dec 13. doi: 10.1038/s41388-018-0624-2

PMCID:: PMC6477891

Abstract Article PDF–5.2M

Select item 625191420.

Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang

Nat Commun. 2018; 9: 4964. Published online 2018 Nov 23. doi: 10.1038/s41467-018-07384-7

PMCID:: PMC6251914

Abstract Article PDF–1.6M

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