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Select item 111345511.

Critical amino acid residues regulating TRPA1 Zn²⁺ response: A comparative study across species

Masaki Matsubara, Yukiko Muraki, Hiroka Suzuki, Noriyuki Hatano, Katsuhiko Muraki

J Biol Chem. 2024 Jun; 300(6): 107302. Published online 2024 Apr 18. doi: 10.1016/j.jbc.2024.107302

PMCID:: PMC11134551

Abstract Article PDF–7.8M

Select item 110740192.

NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells

Julio C. Sánchez, Alexander Alemán, Juan F. Henao, Juan C. Olaya, Barbara E. Ehrlich

J Physiol Biochem. 2024; 80(2): 451–463. Published online 2024 Apr 2. doi: 10.1007/s13105-024-01016-z

PMCID:: PMC11074019

Abstract Article PDF–2.2M

Select item 108700283.

Discovery of PRDM16‐Mediated TRPA1 Induction as the Mechanism for Low Tubulo‐Interstitial Fibrosis in Diabetic Kidney Disease

Fang Xu, Hongwei Jiang, Xiaozhou Li, Jian Pan, Huiling Li, Luxiang Wang, Pan Zhang, Junxiang Chen, Shuangfa Qiu, Yuxin Xie, Yijian Li, Dongshan Zhang, Zheng Dong

Adv Sci (Weinh) 2024 Feb; 11(7): 2306704. Published online 2023 Dec 10. doi: 10.1002/advs.202306704

PMCID:: PMC10870028

Abstract Article PDF–21M

Select item 107881644.

Canine, mouse, and human transient receptor potential ankyrin 1 (TRPA1) channels show different sensitivity to menthol or cold stimulation

Takuya YAMAGUCHI, Kunitoshi UCHIDA, Jun YAMAZAKI

J Vet Med Sci. 2023 Dec; 85(12): 1301–1309. Published online 2023 Oct 11. doi: 10.1292/jvms.23-0327

PMCID:: PMC10788164

Abstract Article PDF–2.7M

Select item 107177365.

FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels

Tomo Kita, Kunitoshi Uchida, Kenichi Kato, Yoshiro Suzuki, Makoto Tominaga, Jun Yamazaki

J Physiol Sci. 2019 Mar; 69(2): 305–316. Published online 2018 Nov 26. doi: 10.1007/s12576-018-0647-z

PMCID:: PMC10717736

Abstract Article PDF–1.4M

Select item 105727256.

Functional TRPA1 Channels Regulate CD56^dimCD16⁺ NK Cell Cytotoxicity against Tumor Cells

Fernanda Scopelliti, Valentina Dimartino, Caterina Cattani, Andrea Cavani

Int J Mol Sci. 2023 Oct; 24(19): 14736. Published online 2023 Sep 29. doi: 10.3390/ijms241914736

PMCID:: PMC10572725

Abstract Article PDF–3.1M

Select item 104717187.

Epigenetic Connections of the TRPA1 Ion Channel in Pain Transmission and Neurogenic Inflammation — a Therapeutic Perspective in Migraine?

Michal Fila, Elzbieta Pawlowska, Joanna Szczepanska, Janusz Blasiak

Mol Neurobiol. 2023; 60(10): 5578–5591. Published online 2023 Jun 16. doi: 10.1007/s12035-023-03428-2

PMCID:: PMC10471718

Abstract Article PDF–1.3M

Select item 104431998.

TRPA1 rare variants in chronic neuropathic and nociplastic pain patients

Margherita Marchi, Erika Salvi, Mirna Andelic, Elkadia Mehmeti, Ilaria D'Amato, Daniele Cazzato, Federica Chiappori, Raffaella Lombardi, Daniele Cartelli, Grazia Devigili, Eleonora Dalla Bella, Monique Gerrits, Rowida Almomani, Rayaz A. Malik, Milena Ślęczkowska, Anna Mazzeo, Luca Gentile, Sulayman Dib-Hajj, Stephen G. Waxman, Catharina G. Faber, Eleonora Vecchio, Marina de Tommaso, Giuseppe Lauria

Pain. 2023 Sep; 164(9): 2048–2059. Published online 2023 Apr 19. doi: 10.1097/j.pain.0000000000002905

PMCID:: PMC10443199

Abstract Article PDF–835K

Select item 103807619.

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel Mediates Acrolein Cytotoxicity in Human Lung Cancer Cells

Akihiko Sakamoto, Yusuke Terui, Kazuei Igarashi, Keiko Kashiwagi

Int J Mol Sci. 2023 Jul; 24(14): 11847. Published online 2023 Jul 24. doi: 10.3390/ijms241411847

PMCID:: PMC10380761

Abstract Article PDF–1.7M

Select item 1025390310.

Activation of TRPA1 in Bladder Suburothelial Myofibroblasts Counteracts TGF-β1-Induced Fibrotic Changes

Mengmeng Zhao, Ning Ding, Haoyu Wang, Shulu Zu, Hanwen Liu, Jiliang Wen, Jiaxin Liu, Nan Ge, Wenzhen Wang, Xiulin Zhang

Int J Mol Sci. 2023 Jun; 24(11): 9501. Published online 2023 May 30. doi: 10.3390/ijms24119501

PMCID:: PMC10253903

Abstract Article PDF–11M

Select item 1019909711.

Molecular mechanism of hyperactivation conferred by a truncation of TRPA1

Avnika Bali, Samantha P. Schaefer, Isabelle Trier, Alice L. Zhang, Lilian Kabeche, Candice E. Paulsen

Nat Commun. 2023; 14: 2867. Published online 2023 May 19. doi: 10.1038/s41467-023-38542-1

PMCID:: PMC10199097

Abstract Article PDF–3.7M

Select item 1017739912.

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as a Sensor of Oxidative Stress in Cancer Cells

Francesco Moccia, Daniela Montagna

Cells. 2023 May; 12(9): 1261. Published online 2023 Apr 26. doi: 10.3390/cells12091261

PMCID:: PMC10177399

Abstract Article PDF–1.9M

Select item 1016022213.

Upregulation of DRG protein TMEM100 facilitates dryskin-induced pruritus by enhancing TRPA1 channel function: Upregulation of TMEM100 facilitates dry skin-induced pruritus

Chao Pan, Yingfu Jiao, Dexu Kong, Haoyue Deng, Saihong Xu, Dan Tang, Wen Yin, Po Gao, Weifeng Yu, Yinghui Fan, Daxiang Wen

Acta Biochim Biophys Sin (Shanghai) 2023 Mar; 55(3): 404–416. Published online 2022 Dec 8. doi: 10.3724/abbs.2022180

PMCID:: PMC10160222

Abstract Article PDF–3.4M

Select item 996999014.

Mechanisms and Consequences of Variable TRPA1 Expression by Airway Epithelial Cells: Effects of TRPV1 Genotype and Environmental Agonists on Cellular Responses to Pollutants in Vitro and Asthma

Emmanuel Rapp, Zhenyu Lu, Lili Sun, Samantha N. Serna, Marysol Almestica-Roberts, Katherine L. Burrell, Nam D. Nguyen, Cassandra E. Deering-Rice, Christopher A. Reilly

Environ Health Perspect. 2023 Feb; 131(2): 027009. Published online 2023 Feb 27. doi: 10.1289/EHP11076

PMCID:: PMC9969990

Abstract Article PDF–1.7M

Select item 995726315.

Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review

Fulvio Celsi, Francesca Peri, Julia Cavasin, Luisa Zupin, Giorgio Cozzi, Egidio Barbi, Sergio Crovella

Genes (Basel) 2023 Feb; 14(2): 411. Published online 2023 Feb 4. doi: 10.3390/genes14020411

PMCID:: PMC9957263

Abstract Article PDF–3.4M

Select item 992490716.

TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy

Aida Marcotti, Jorge Fernández-Trillo, Alejandro González, Marta Vizcaíno-Escoto, Pablo Ros-Arlanzón, Luz Romero, José Miguel Vela, Ana Gomis, Félix Viana, Elvira de la Peña

Brain. 2023 Feb; 146(2): 475–491. Published online 2022 Jul 24. doi: 10.1093/brain/awac273