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Select item 111595101.

Enhanced SMYD3 expression is essential for the growth of breast cancer cells

Ryuji Hamamoto, Fabio Pittella Silva, Masataka Tsuge, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura, Yoichi Furukawa

Cancer Sci. 2006 Feb; 97(2): 113–118. Published online 2006 Jan 25. doi: 10.1111/j.1349-7006.2006.00146.x

PMCID:: PMC11159510

Abstract Article PDF–280K

Select item 111586912.

Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking

Haijian Wang, Yang Liu, Wen Tan, Yang Zhang, Naiqing Zhao, Yan Jiang, Chengzhao Lin, Bingtao Hao, Dan Zhao, Ji Qian, Daru Lu, Li Jin, Qingyi Wei, Dongxin Lin, Fuchu He

Cancer Sci. 2008 Apr; 99(4): 787–791. Published online 2008 Feb 21. doi: 10.1111/j.1349-7006.2008.00729.x

PMCID:: PMC11158691

Abstract Article PDF–101K

Select item 109784923.

SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation

Tatjana Sajic, Chayenne Karine Ferreira Gomes, Marie Gasser, Tiziana Caputo, Nasim Bararpour, Esther Landaluce-Iturriria, Marc Augsburger, Nadia Walter, Alexandre Hainard, Isabel C. Lopez-Mejia, Tony Fracasso, Aurélien Thomas, Federica Gilardi

Int J Obes (Lond) 2024; 48(4): 557–566. Published online 2023 Dec 26. doi: 10.1038/s41366-023-01450-x

PMCID:: PMC10978492

Abstract Article PDF–2.7M

Select item 106880754.

The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback

Lei Yu, Yi Wei, Tong Lu, Zhengqi Li, Shimin Lai, Yan Yan, Changhui Chen, Weiping Wen

Cell Commun Signal. 2023; 21: 345. Published online 2023 Nov 30. doi: 10.1186/s12964-023-01375-y

PMCID:: PMC10688075

Abstract Article PDF–4.4M

Select item 104077665.

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

Nupur Nigam, Benjamin Bernard, Samantha Sevilla, Sohyoung Kim, Mohd Saleem Dar, Daniel Tsai, Yvette Robbins, Kyunghee Burkitt, Cem Sievers, Clint T. Allen, Richard L. Bennett, Theophilus T. Tettey, Benjamin Carter, Lorenzo Rinaldi, Mark W. Lingen, Houssein Sater, Elijah F. Edmondson, Arfa Moshiri, Abbas Saeed, Hui Cheng, Xiaolin Luo, Kevin Brennan, Vishal Koparde, Chen Chen, Sudipto Das, Thorkell Andresson, Abdalla Abdelmaksoud, Madhavi Murali, Seiji Sakata, Kengo Takeuchi, Raj Chari, Yusuke Nakamura, Ravindra Uppaluri, John B. Sunwoo, Carter Van Waes, Jonathan D. Licht, Gordon L. Hager, Vassiliki Saloura

Cell Rep. Author manuscript; available in PMC 2023 Aug 8.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112823. Published online 2023 Jul 17. doi: 10.1016/j.celrep.2023.112823

PMCID:: PMC10407766

Abstract Article PDF–2.2M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102239397.

Histone lysine methyltransferase SMYD3 promotes oral squamous cell carcinoma tumorigenesis via H3K4me3-mediated HMGA2 transcription

Zongcheng Yang, Fen Liu, Zongkai Li, Nianping Liu, Xinfeng Yao, Yu Zhou, Liyu Zhang, Pan Jiang, Honghong Liu, Lingming Kong, Chuandong Lang, Xin Xu, Jihui Jia, Takahito Nakajima, Wenchao Gu, Lixin Zheng, Zhihong Zhang

Clin Epigenetics. 2023; 15: 92. Published online 2023 May 26. doi: 10.1186/s13148-023-01506-9

PMCID:: PMC10223939

Abstract Article PDF–12M

Select item 97956228.

SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells

Yang Yang, Rongfang Qiu, Siyu Zhao, Lin Shen, Bufu Tang, Qiaoyou Weng, Ziwei Xu, Liyun Zheng, Weiqian Chen, Gaofeng Shu, Yajie Wang, Zhongwei Zhao, Minjiang Chen, Jiansong Ji

BMC Biol. 2022; 20: 294. Published online 2022 Dec 27. doi: 10.1186/s12915-022-01499-6

PMCID:: PMC9795622

Abstract Article PDF–8.0M

Select item 97696989.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 969204510.

Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity

Zixuan Wang, Xiaoyun Chen, Sijia Fan, Chunchun Zhu, Hongyan Deng, Jinhua Tang, Xueyi Sun, Shuke Jia, Qian Liao, Wuhan Xiao, Xing Liu

J Biol Chem. 2022 Dec; 298(12): 102633. Published online 2022 Oct 21. doi: 10.1016/j.jbc.2022.102633

PMCID:: PMC9692045

Abstract Article PDF–6.4M

Select item 944089511.

SMYD3 promotes aerobic glycolysis in diffuse large B-cell lymphoma via H3K4me3-mediated PKM2 transcription

Tian Tian, Jiwei Li, Di Shi, Yupeng Zeng, Baohua Yu, Xiaoqiu Li, Ping Wei, Xiaoyan Zhou

Cell Death Dis. 2022 Sep; 13(9): 763. Published online 2022 Sep 3. doi: 10.1038/s41419-022-05208-7

PMCID:: PMC9440895

Abstract Article PDF–5.4M

Select item 943756312.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 934857613.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928514.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 889702215.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 884216516.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 831454717.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 830258418.

SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters

Heyun Zhang, Zhangyu Zheng, Rongqin Zhang, Yongcong Yan, Yaorong Peng, Hua Ye, Lehang Lin, Junyao Xu, Wenbin Li, Pinbo Huang

Cell Death Dis. 2021 Aug; 12(8): 731. Published online 2021 Jul 23. doi: 10.1038/s41419-021-04009-8

Correction in:: Cell Death Dis. 2021 Sep; 12(9): 793.

PMCID:: PMC8302584

Abstract Article PDF–3.1M

Select item 826793819.

Mechanism of the Conformational Change of the Protein Methyltransferase SMYD3: A Molecular Dynamics Simulation Study

Jixue Sun, Zibin Li, Na Yang

Int J Mol Sci. 2021 Jul; 22(13): 7185. Published online 2021 Jul 2. doi: 10.3390/ijms22137185

PMCID:: PMC8267938

Abstract Article PDF–3.5M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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