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Items: 1 to 20 of 83

1.
Identification of endothelial and mesenchymal FOXF1 enhancers involved in alveolar capillary dysplasia
Guolun Wang, Bingqiang Wen, Minzhe Guo, Enhong Li, Yufang Zhang, Jeffrey A. Whitsett, Tanya V. Kalin, Vladimir V. Kalinichenko
Nat Commun. 2024; 15: 5233. Published online 2024 Jun 19. doi: 10.1038/s41467-024-49477-6
PMCID:
PMC11187179
AbstractArticlePDF–4.6M
2.
FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4
Fenghua Bian, Chinmayee Goda, Guolun Wang, Ying-Wei Lan, Zicheng Deng, Wen Gao, Anusha Acharya, Abid A Reza, Jose Gomez-Arroyo, Nawal Merjaneh, Xiaomeng Ren, Jermaine Goveia, Peter Carmeliet, Vladimir V Kalinichenko, Tanya V Kalin
EMBO Mol Med. 2024 May; 16(5): 1063–1090. Published online 2024 Apr 8. doi: 10.1038/s44321-024-00064-8
PMCID:
PMC11099127
AbstractArticlePDF–18M
3.
Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension
Sarasa Isobe, Ramesh V. Nair, Helen Y. Kang, Lingli Wang, Jan-Renier Moonen, Tsutomu Shinohara, Aiqin Cao, Shalina Taylor, Shoichiro Otsuki, David P. Marciano, Rebecca L. Harper, Mir S. Adil, Chongyang Zhang, Mauro Lago-Docampo, Jakob Körbelin, Jesse M. Engreitz, Michael P. Snyder, Marlene Rabinovitch
Nat Commun. 2023; 14: 7578. Published online 2023 Nov 21. doi: 10.1038/s41467-023-43039-y
PMCID:
PMC10663616
AbstractArticlePDF–5.1M
4.
GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter
Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert
Development. 2022 Aug 1; 149(15): dev200522. Published online 2022 Jul 29. doi: 10.1242/dev.200522
PMCID:
PMC10656427
AbstractArticle
5.
The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis
Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang
Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667
PMCID:
PMC10655918
AbstractArticle
6.
CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression
Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler
Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059
Correction in:
Cardiovasc Res. 2024 Jan; 120(1): 120.
PMCID:
PMC10478754
AbstractArticlePDF–21M
7.
Three-dimensional molecular architecture of mouse organogenesis
Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng
Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7
PMCID:
PMC10390492
AbstractArticlePDF–13M
8.
FOXF1 Regulates Alveolar Epithelial Morphogenesis through Transcriptional Activation of Mesenchymal WNT5A
Abid A. Reza, Fatemeh Kohram, Hasan A. Reza, Timothy R. Kalin, Paranthaman S. Kannan, William J. Zacharias, Vladimir V. Kalinichenko
Am J Respir Cell Mol Biol. 2023 Apr 1; 68(4): 430–443. Published online 2022 Dec 21. doi: 10.1165/rcmb.2022-0191OC
PMCID:
PMC10112422
AbstractArticlePDF–3.3M
9.
Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis
Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai
Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y
PMCID:
PMC9381504
AbstractArticlePDF–6.6M
10.
Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling
Guolun Wang, Bingqiang Wen, Zicheng Deng, Yufang Zhang, Olena A. Kolesnichenko, Vladimir Ustiyan, Arun Pradhan, Tanya V. Kalin, Vladimir V. Kalinichenko
Nat Commun. 2022; 13: 2080. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29746-y
PMCID:
PMC9019054
AbstractArticlePDF–6.3M
11.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
12.
GLI transcriptional repression is inert prior to Hedgehog pathway activation
Rachel K. Lex, Weiqiang Zhou, Zhicheng Ji, Kristin N. Falkenstein, Kaleigh E. Schuler, Kathryn E. Windsor, Joseph D. Kim, Hongkai Ji, Steven A. Vokes
Nat Commun. 2022; 13: 808. Published online 2022 Feb 10. doi: 10.1038/s41467-022-28485-4
PMCID:
PMC8831537
AbstractArticlePDF–3.8M
13.
Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis
Russell R. Braeuer, Natalie M. Walker, Keizo Misumi, Serina Mazzoni-Putman, Yoshiro Aoki, Ruohan Liao, Ragini Vittal, Gabriel G. Kleer, David S. Wheeler, Jonathan Z. Sexton, Carol F. Farver, Joshua D. Welch, Vibha N. Lama
J Clin Invest. 2021 Nov 1; 131(21): e147343. Published online 2021 Nov 1. doi: 10.1172/JCI147343
PMCID:
PMC8553552
AbstractArticlePDF–9.5M
14.
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient
Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida
Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6
PMCID:
PMC8528819
AbstractArticlePDF–3.6M
15.
Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development
Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang
Front Cell Dev Biol. 2021; 9: 665109. Published online 2021 Apr 8. doi: 10.3389/fcell.2021.665109
PMCID:
PMC8060495
AbstractArticlePDF–4.3M
16.
Disruption of a Hedgehog-Foxf1-Rspo2 signaling axis leads to tracheomalacia and a loss of Sox9+ tracheal chondrocytes
Talia Nasr, Andrea M. Holderbaum, Praneet Chaturvedi, Kunal Agarwal, Jessica L. Kinney, Keziah Daniels, Stephen L. Trisno, Vladimir Ustiyan, John M. Shannon, James M. Wells, Debora Sinner, Vladimir V. Kalinichenko, Aaron M. Zorn
Dis Model Mech. 2021 Feb 1; 14(2): dmm046573. Published online 2021 Feb 4. doi: 10.1242/dmm.046573
PMCID:
PMC7875488
AbstractArticle
17.
Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike, Talia Nasr, Kentaro Iwasawa, Kirsten Giesbrecht, Phillip C. Witcher, Alexandra Eicher, Lauren Haines, Yarim Lee, John M. Shannon, Mitsuru Morimoto, James M. Wells, Takanori Takebe, Aaron M. Zorn
Nat Commun. 2020; 11: 4158. Published online 2020 Aug 27. doi: 10.1038/s41467-020-17968-x
PMCID:
PMC7453027
AbstractArticlePDF–6.5M
18.
Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells
Keishi Kishimoto, Kana T. Furukawa, Agustin Luz-Madrigal, Akira Yamaoka, Chisa Matsuoka, Masanobu Habu, Cantas Alev, Aaron M. Zorn, Mitsuru Morimoto
Nat Commun. 2020; 11: 4159. Published online 2020 Aug 27. doi: 10.1038/s41467-020-17969-w
PMCID:
PMC7453000
AbstractArticlePDF–8.9M
19.
Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway
Jaroslav Fabik, Katarina Kovacova, Zbynek Kozmik, Ondrej Machon
Biol Open. 2020 Jun 15; 9(6): bio052043. Published online 2020 Jun 25. doi: 10.1242/bio.052043
PMCID:
PMC7331463
AbstractArticlePDF–30M
20.
Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans and loss of Foxf1 and Foxf2 results in gastroparesis in mice
B. Paul Herring, April M. Hoggatt, Anita Gupta, John M. Wo
Neurogastroenterol Motil. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Neurogastroenterol Motil. 2019 Mar; 31(3): e13528. Published online 2018 Dec 19. doi: 10.1111/nmo.13528
PMCID:
PMC6821388
AbstractArticlePDF–2.5M

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