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Items: 1 to 20 of 34

1.
SOX17 is a Critical Factor in Maintaining Endothelial Function in Pulmonary Hypertension by an Exosome‐Mediated Autocrine Manner
Xiaozhou Zou, Ting Liu, Zhongjie Huang, Wei Zhou, Mengnan Yuan, Hongying Zhao, Zongfu Pan, Pengcheng Chen, Yanfei Shao, Xiaoping Hu, Su Zhang, Shuilian Zheng, Yiwen Zhang, Ping Huang
Adv Sci (Weinh) 2023 May; 10(14): 2206139. Published online 2023 Mar 15. doi: 10.1002/advs.202206139
PMCID:
PMC10190640
AbstractArticlePDF–10M
2.
SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics
Shreya Sangam, Xutong Sun, Tae-Hwi Schwantes-An, Manivannan Yegambaram, Qing Lu, Yinan Shi, Todd Cook, Amanda Fisher, Andrea L. Frump, Anna Coleman, Yanan Sun, Shuxin Liang, Howard Crawford, Katie A. Lutz, Avinash D. Maun, Michael W. Pauciulo, Jason H. Karnes, Ketul R. Chaudhary, Duncan J. Stewart, Paul R. Langlais, Mohit Jain, Mona Alotaibi, Tim Lahm, Yan Jin, Haiwei Gu, Haiyang Tang, William C. Nichols, Stephen M. Black, Ankit A. Desai
Am J Respir Crit Care Med. 2023 Apr 15; 207(8): 1055–1069. Published online 2023 Mar 13. doi: 10.1164/rccm.202203-0450OC
PMCID:
PMC10112457
AbstractArticlePDF–2.9M
3.
Upregulated miR-194-5p suppresses retinal microvascular endothelial cell dysfunction and mitigates the symptoms of hypertensive retinopathy in mice by targeting SOX17 and VEGF signaling
Qianqian Wan, Heting Liu, Yuxin Xu, Qing Zhang, Liming Tao
Cell Cycle. 2023; 22(3): 331–346. Published online 2022 Oct 5. doi: 10.1080/15384101.2022.2119514
PMCID:
PMC9851258
AbstractArticlePDF–2.6M
4.
Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling
Chan Soon Park, Soo Hyun Kim, Hae Young Yang, Ju-Hee Kim, Ralph Theo Schermuly, Ye Seul Cho, Hyejeong Kang, Jae-Hyeong Park, Eunhyeong Lee, HyeonJin Park, Jee Myung Yang, Tae Wook Noh, Seung-Pyo Lee, Sun Sik Bae, Jinju Han, Young Seok Ju, Jun-Bean Park, Injune Kim
Circ Res. 2022 Oct 28; 131(10): 792–806. Published online 2022 Oct 7. doi: 10.1161/CIRCRESAHA.122.320845
PMCID:
PMC9612711
AbstractArticlePDF–8.2M
5.
SOX17 enhancer variants disrupt transcription factor binding and enhancer inactivity drives pulmonary hypertension
Rachel Walters, Eleni Vasilaki, Jurjan Aman, Chien-Nien Chen, Yukyee Wu, Olin D Liang, Ali Ashek, Olivier Dubois, Lin Zhao, Farah Sabrin, Inês Cebola, Jorge Ferrer, Nicholas W Morrell, James R Klinger, Martin R Wilkins, Lan Zhao, Christopher J Rhodes
Circulation. Author manuscript; available in PMC 2023 May 25.
Published in final edited form as: Circulation. 2023 May 23; 147(21): 1606–1621. Published online 2023 Apr 17. doi: 10.1161/CIRCULATIONAHA.122.061940
PMCID:
PMC7614572
AbstractArticlePDF–3.0M
6.
Common genetic variants in pulmonary arterial hypertension
Sue Gu, Rahul Kumar, Michael H Lee, Claudia Mickael, Brian B Graham
Lancet Respir Med. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Lancet Respir Med. 2019 Mar; 7(3): 190–191. Published online 2018 Dec 5. doi: 10.1016/S2213-2600(18)30448-X
PMCID:
PMC6768546
ArticlePDF–279K
7.
Associations among Genetic Variants and Intracranial Aneurysm in a Chinese Population
Bingyang Li, Chongyu Hu, Junyu Liu, Xin Liao, Jiayu Xun, Manqian Xiao, Junxia Yan
Yonsei Med J. 2019 Jul 1; 60(7): 651–658. Published online 2019 Jun 24. doi: 10.3349/ymj.2019.60.7.651
PMCID:
PMC6597466
AbstractArticlePDF–399K
8.
Genetic polymorphisms in Sox17 associated with intracranial aneurysm in Chinese Han people: a genotype-phenotype study
Mengqi Li, Weihan Wang, Lin Zhang, Wenqiang Xin, Yan Zhao, Linchun Huan, Jianjun Yu, Hao Zhang, Jianning Zhang, Shuyuan Yang, Degang Liang, Weidong Yang, Xinyu Yang
Neuropsychiatr Dis Treat. 2019; 15: 779–783. Published online 2019 Apr 2. doi: 10.2147/NDT.S193478
Correction in:
Neuropsychiatr Dis Treat. 2019; 15: 2291.
PMCID:
PMC6452799
AbstractArticlePDF–199K
9.
Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease
Na Zhu, Carrie L. Welch, Jiayao Wang, Philip M. Allen, Claudia Gonzaga-Jauregui, Lijiang Ma, Alejandra K. King, Usha Krishnan, Erika B. Rosenzweig, D. Dunbar Ivy, Eric D. Austin, Rizwan Hamid, Michael W. Pauciulo, Katie A. Lutz, William C. Nichols, Jeffrey G. Reid, John D. Overton, Aris Baras, Frederick E. Dewey, Yufeng Shen, Wendy K. Chung
Genome Med. 2018; 10: 56. Published online 2018 Jul 20. doi: 10.1186/s13073-018-0566-x
PMCID:
PMC6054746
AbstractArticlePDF–823K
10.
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen M. Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala Aldred, Harm J. Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gabor Kovacs, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke-Zaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell
Nat Commun. 2018; 9: 1416. Published online 2018 Apr 12. doi: 10.1038/s41467-018-03672-4
PMCID:
PMC5897357
AbstractArticlePDF–7.2M
11.
A regulatory network controls nephrocan expression and midgut patterning
Juan Hou, Wei Wei, Ranajeet S. Saund, Ping Xiang, Thomas J. Cunningham, Yuyin Yi, Olivia Alder, Daphne Y. D. Lu, Joanne G. A. Savory, Nicole A. J. Krentz, Rachel Montpetit, Rebecca Cullum, Nicole Hofs, David Lohnes, R. Keith Humphries, Yojiro Yamanaka, Gregg Duester, Yukio Saijoh, Pamela A. Hoodless
Development. 2014 Oct; 141(19): 3772–3781. doi: 10.1242/dev.108274
PMCID:
PMC4197584
AbstractArticle
12.
Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk
Tatiana Foroud, Daniel L. Koller, Dongbing Lai, Laura Sauerbeck, Craig Anderson, Nerissa Ko, Ranjan Deka, Thomas H. Mosley, Myriam Fornage, Daniel Woo, Charles J. Moomaw, Richard Hornung, John Huston, Irene Meissner, Joan E. Bailey-Wilson, Carl Langefeld, Guy Rouleau, E. Sander Connolly, Bradford B. Worrall, Dawn Kleindorfer, Matthew L. Flaherty, Sharyl Martini, Jason Mackey, Felipe De Los Rios La Rosa, Robert D. Brown, Jr, Joseph P. Broderick, the FIA Study Investigators
Stroke. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Stroke. 2012 Nov; 43(11): 2846–2852. Published online 2012 Sep 6. doi: 10.1161/STROKEAHA.112.656397
PMCID:
PMC3752852
AbstractArticlePDF–1.3M
13.
Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation
Chanchao Lorthongpanich, Daniel M. Messerschmidt, Siew Wee Chan, Wanjin Hong, Barbara B. Knowles, Davor Solter
Genes Dev. 2013 Jul 1; 27(13): 1441–1446. doi: 10.1101/gad.219618.113
PMCID:
PMC3713425
AbstractArticlePDF–732K
14.
The primitive endoderm lineage of the mouse blastocyst: Sequential transcription factor activation and regulation of differentiation by Sox17
Jérôme Artus, Anna Piliszek, Anna-Katerina Hadjantonakis
Dev Biol. Author manuscript; available in PMC 2012 Oct 1.
Published in final edited form as: Dev Biol. 2011 Feb 15; 350(2): 393–404. Published online 2010 Dec 10. doi: 10.1016/j.ydbio.2010.12.007
PMCID:
PMC3461954
AbstractArticlePDF–2.6M
15.
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements
Calista K. L. Ng, Noel X. Li, Sheena Chee, Shyam Prabhakar, Prasanna R. Kolatkar, Ralf Jauch
Nucleic Acids Res. 2012 Jun; 40(11): 4933–4941. Published online 2012 Feb 16. doi: 10.1093/nar/gks153
PMCID:
PMC3367189
AbstractArticlePDF–1.6M
16.
The Transcription Factor SOX18 Regulates the Expression of Matrix Metalloproteinase 7 and Guidance Molecules in Human Endothelial Cells
Martina Hoeth, Heide Niederleithner, Renate Hofer-Warbinek, Martin Bilban, Herbert Mayer, Ulrike Resch, Christof Lemberger, Oswald Wagner, Erhard Hofer, Peter Petzelbauer, Rainer de Martin
PLoS One. 2012; 7(1): e30982. Published online 2012 Jan 23. doi: 10.1371/journal.pone.0030982
PMCID:
PMC3264645
AbstractArticlePDF–579K
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Mutations in SOX17 are Associated with Congenital Anomalies of the Kidney and the Urinary Tract
Stefania Gimelli, Gianluca Caridi, Silvana Beri, Kyle McCracken, Renata Bocciardi, Paola Zordan, Monica Dagnino, Patrizia Fiorio, Luisa Murer, Elisa Benetti, Orsetta Zuffardi, Roberto Giorda, James M Wells, Giorgio Gimelli, Gian Marco Ghiggeri
Hum Mutat. 2010 Dec; 31(12): 1352–1359. Published online 2010 Oct 19. doi: 10.1002/humu.21378
PMCID:
PMC3056145
AbstractArticlePDF–340K
19.
Differential Gene Expression Profiling of Cultured neu-Transformed Versus Spontaneously-Transformed Rat Cholangiocytes and of Corresponding Cholangiocarcinomas
Catherine I. Dumur, Deanna J.W. Campbell, Jennifer L. DeWitt, Regina A. Oyesanya, Alphonse E. Sirica
Exp Mol Pathol. Author manuscript; available in PMC 2011 Dec 1.
Published in final edited form as: Exp Mol Pathol. 2010 Dec; 89(3): 227–235. Published online 2010 Sep 9. doi: 10.1016/j.yexmp.2010.08.007
PMCID:
PMC2981699
AbstractArticlePDF–990K
20.
Sox17 modulates Wnt3A/β-catenin-mediated transcriptional activation of the Lef-1 promoter
Xiaoming Liu, Meihui Luo, Weiliang Xie, James M. Wells, Michael J. Goodheart, John F. Engelhardt
Am J Physiol Lung Cell Mol Physiol. 2010 Nov; 299(5): L694–L710. Published online 2010 Aug 27. doi: 10.1152/ajplung.00140.2010
PMCID:
PMC2980392
AbstractArticle

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