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Select item 109285741.

Cell type‐specific regulation of m⁶A modified RNAs in the aging Drosophila brain

Alexandra E. Perlegos, China N. Byrns, Nancy M. Bonini

Aging Cell. 2024 Mar; 23(3): e14076. Published online 2024 Jan 11. doi: 10.1111/acel.14076

PMCID:: PMC10928574

Abstract Article PDF–17M

Select item 105938102.

Phase separation of BuGZ regulates gut regeneration and aging through interaction with m⁶A regulators

Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, Hao Jiang

Nat Commun. 2023; 14: 6700. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42474-1

PMCID:: PMC10593810

Abstract Article PDF–3.5M

Select item 101923613.

Indel driven rapid evolution of core nuclear pore protein gene promoters

David W. J. McQuarrie, Adam M. Read, Frannie H. S. Stephens, Alberto Civetta, Matthias Soller

Sci Rep. 2023; 13: 8035. Published online 2023 May 17. doi: 10.1038/s41598-023-34985-0

PMCID:: PMC10192361

Abstract Article PDF–2.2M

Select item 97922434.

METTL14 Regulates Intestine Cellular Senescence through m⁶A Modification of Lamin B Receptor

Zizhen Zhang, Meng Xue, Jingyu Chen, Zhuo Wang, Fangyu Ju, Jiaojiao Ni, Jiawei Sun, Haoyue Wu, Huimei Zheng, Ziwei Lou, Yawen Zhang, Xiaohang Yang, Shujie Chen, Yongmei Xi, Liangjing Wang

Oxid Med Cell Longev. 2022; 2022: 9096436. Published online 2022 Dec 19. doi: 10.1155/2022/9096436

PMCID:: PMC9792243

Abstract Article PDF–2.7M

Select item 94745455.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 88440456.

Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay

Guoqiang Zhang, Yongru Xu, Xiaona Wang, Yuanxiang Zhu, Liangliang Wang, Wenxin Zhang, Yiru Wang, Yajie Gao, Xuna Wu, Ying Cheng, Qinmiao Sun, Dahua Chen

Nat Commun. 2022; 13: 859. Published online 2022 Feb 14. doi: 10.1038/s41467-022-28547-7

PMCID:: PMC8844045

Abstract Article PDF–4.5M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 85342958.

A Candidate RNAi Screen Reveals Diverse RNA-Binding Protein Phenotypes in Drosophila Flight Muscle

Shao-Yen Kao, Elena Nikonova, Sabrina Chaabane, Albiona Sabani, Alexandra Martitz, Anja Wittner, Jakob Heemken, Tobias Straub, Maria L. Spletter

Cells. 2021 Oct; 10(10): 2505. Published online 2021 Sep 22. doi: 10.3390/cells10102505

PMCID:: PMC8534295

Abstract Article PDF–9.7M

Select item 82137279.

Hakai is required for stabilization of core components of the m⁶A mRNA methylation machinery

Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant

Nat Commun. 2021; 12: 3778. Published online 2021 Jun 18. doi: 10.1038/s41467-021-23892-5

PMCID:: PMC8213727

Abstract Article PDF–5.4M

Select item 804185110.

Role of Hakai in m⁶A modification pathway in Drosophila

Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan

Nat Commun. 2021; 12: 2159. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22424-5

PMCID:: PMC8041851

Abstract Article PDF–3.1M

Select item 795840011.

mTORC1-chaperonin CCT signaling regulates m⁶A RNA methylation to suppress autophagy

Hong-Wen Tang, Jui-Hsia Weng, Wen Xing Lee, Yanhui Hu, Lei Gu, Sungyun Cho, Gina Lee, Richard Binari, Cathleen Li, Min En Cheng, Ah-Ram Kim, Jun Xu, Zhangfei Shen, Chiwei Xu, John M. Asara, John Blenis, Norbert Perrimon

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2021945118. Published online 2021 Mar 1. doi: 10.1073/pnas.2021945118

PMCID:: PMC7958400

Abstract Article PDF–1.8M

Select item 793587312.

A neural m⁶A/Ythdf pathway is required for learning and memory in Drosophila

Lijuan Kan, Stanislav Ott, Brian Joseph, Eun Sil Park, Wei Dai, Ralph E. Kleiner, Adam Claridge-Chang, Eric C. Lai

Nat Commun. 2021; 12: 1458. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21537-1

Correction in:: Nat Commun. 2021; 12: 1743.

PMCID:: PMC7935873

Abstract Article PDF–4.4M

Select item 788305613.

Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila

Lina Worpenberg, Chiara Paolantoni, Sara Longhi, Miriam M Mulorz, Tina Lence, Hans‐Hermann Wessels, Erik Dassi, Giuseppe Aiello, F X Reymond Sutandy, Marion Scheibe, Raghu R Edupuganti, Anke Busch, Martin M Möckel, Michiel Vermeulen, Falk Butter, Julian König, Michela Notarangelo, Uwe Ohler, Christoph Dieterich, Alessandro Quattrone, Alessia Soldano, Jean‐Yves Roignant

EMBO J. 2021 Feb 15; 40(4): e104975. Published online 2021 Jan 11. doi: 10.15252/embj.2020104975

PMCID:: PMC7883056

Abstract Article PDF–2.8M

Select item 733279814.

The 18S ribosomal RNA m⁶A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

Jessica Leismann, Mariangela Spagnuolo, Mihika Pradhan, Ludivine Wacheul, Minh Anh Vu, Michael Musheev, Pablo Mier, Miguel A Andrade‐Navarro, Marc Graille, Christof Niehrs, Denis LJ Lafontaine, Jean‐Yves Roignant

EMBO Rep. 2020 Jul 3; 21(7): e49443. Published online 2020 Apr 29. doi: 10.15252/embr.201949443

PMCID:: PMC7332798

Abstract Article PDF–1.8M

Select item 590644915.

The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster

Lisa Jehrke, Fiona A. Stewart, Andrea Droste, Mathias Beller

Sci Rep. 2018; 8: 6215. Published online 2018 Apr 18. doi: 10.1038/s41598-018-24542-5

PMCID:: PMC5906449

Abstract Article PDF–4.5M

Select item 590071416.

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m⁶A machinery component Wtap/Fl(2)d

Philip Knuckles, Tina Lence, Irmgard U. Haussmann, Dominik Jacob, Nastasja Kreim, Sarah H. Carl, Irene Masiello, Tina Hares, Rodrigo Villaseñor, Daniel Hess, Miguel A. Andrade-Navarro, Marco Biggiogera, Mark Helm, Matthias Soller, Marc Bühler, Jean-Yves Roignant

Genes Dev. 2018 Mar 1; 32(5-6): 415–429. doi: 10.1101/gad.309146.117

PMCID:: PMC5900714

Abstract Article PDF–8.4M

Select item 588966117.

Xio is a component of the Drosophila sex determination pathway and RNA N⁶-methyladenosine methyltransferase complex

Jian Guo, Hong-Wen Tang, Jing Li, Norbert Perrimon, Dong Yan

Proc Natl Acad Sci U S A. 2018 Apr 3; 115(14): 3674–3679. Published online 2018 Mar 19. doi: 10.1073/pnas.1720945115

PMCID:: PMC5889661

Abstract Article PDF–1.4M

Select item 570780518.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900219.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 550088920.

The m⁶A pathway facilitates sex determination in Drosophila

Lijuan Kan, Anya V. Grozhik, Jeffrey Vedanayagam, Deepak P. Patil, Nan Pang, Kok-Seong Lim, Yi-Chun Huang, Brian Joseph, Ching-Jung Lin, Vladimir Despic, Jian Guo, Dong Yan, Shu Kondo, Wu-Min Deng, Peter C. Dedon, Samie R. Jaffrey, Eric C. Lai

Nat Commun. 2017; 8: 15737. Published online 2017 Jul 4. doi: 10.1038/ncomms15737

PMCID:: PMC5500889

Abstract Article PDF–2.9M

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