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Items: 1 to 20 of 145

1.
HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14
William J. Blakely, Joshua Hatterschide, Elizabeth A. White
mBio. 2024 Oct; 15(10): e01811-24. Published online 2024 Sep 9. doi: 10.1128/mbio.01811-24
PMCID:
PMC11481495
AbstractArticlePDF–2.8M
2.
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo
Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361
PMCID:
PMC11373599
AbstractArticlePDF–11M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
4.
Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer
Shasha Li, Lulu Wang, Jing Shi, Yi Chen, Ang Xiao, Bingyue Huo, Wenjing Tian, Shilu Zhang, Gang Yang, Wensheng Gong, Huixia Zhang
PeerJ. 2024; 12: e16752. Published online 2024 Jan 10. doi: 10.7717/peerj.16752
PMCID:
PMC10787542
AbstractArticlePDF–13M
5.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
6.
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development
Yifang Hu, Rihua Zhang, Shan Lu, Wensong Zhang, Dan Wang, Yaoqi Ge, Feng Jiang, Xiaoxuan Qin, Yun Liu
Int J Biol Sci. 2023; 19(7): 2034–2052. Published online 2023 Apr 2. doi: 10.7150/ijbs.79924
PMCID:
PMC10158029
AbstractArticlePDF–7.9M
7.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
8.
WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein
Jianping Zou, Ling Zhou, Yi Le, Zhi Fang, Min Zhong, Fengting Nie, Xianpin Wei, Xiaomei Zhang, Zhen Chen, Lingling Cai, Heng Wang, Jianping Xiong, Ziling Fang, Xiaojun Xiang
Cell Commun Signal. 2023; 21: 38. Published online 2023 Feb 17. doi: 10.1186/s12964-023-01050-2
PMCID:
PMC9938551
AbstractArticlePDF–11M
9.
Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas
Joseph G. Kern, Andrew M. Tilston-Lunel, Anthony Federico, Boting Ning, Amy Mueller, Grace B. Peppler, Eleni Stampouloglou, Nan Cheng, Randy L. Johnson, Marc E. Lenburg, Jennifer E. Beane, Stefano Monti, Xaralabos Varelas
Nat Commun. 2022; 13: 7198. Published online 2022 Nov 28. doi: 10.1038/s41467-022-34864-8
PMCID:
PMC9705439
AbstractArticlePDF–6.2M
10.
Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma
David Romano, Lucía García-Gutiérrez, Nourhan Aboud, David J Duffy, Keith T Flaherty, Dennie T Frederick, Walter Kolch, David Matallanas
Life Sci Alliance. 2022 Oct; 5(10): e202201445. Published online 2022 Aug 29. doi: 10.26508/lsa.202201445
PMCID:
PMC9434705
AbstractArticlePDF–2.0M
11.
TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein
Yongbin Lu, Yi Xiao, Jingru Yang, Hongxin Su, Xiaobin Zhang, Fei Su, Baohong Tian, Da Zhao, Xiaoling Ling, Tao Zhang
Oxid Med Cell Longev. 2022; 2022: 4374978. Published online 2022 Aug 17. doi: 10.1155/2022/4374978
PMCID:
PMC9402307
AbstractArticlePDF–3.2M
12.
Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas
Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3
PMCID:
PMC9360443
AbstractArticlePDF–5.8M
13.
LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells
Emi Fujibayashi, Satomi Mukai, Kosuke Torigata, Yumi Ando, Toshihiro Uchihashi, Masami Nozaki, Susumu Tanaka, Masato Okada, Mikihiko Kogo, Hiroshi Nojima, Norikazu Yabuta
Sci Rep. 2022; 12: 12363. Published online 2022 Jul 20. doi: 10.1038/s41598-022-16667-5
PMCID:
PMC9300623
AbstractArticlePDF–12M
14.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
15.
Oxidative stress-CBP axis modulates MOB1 acetylation and activates the Hippo signaling pathway
Jiaqi Jin, Lei Zhang, Xueying Li, Weizhi Xu, Siyuan Yang, Jiagui Song, Wenhao Zhang, Jun Zhan, Jianyuan Luo, Hongquan Zhang
Nucleic Acids Res. 2022 Apr 22; 50(7): 3817–3834. Published online 2022 Mar 29. doi: 10.1093/nar/gkac189
PMCID:
PMC9023286
AbstractArticlePDF–4.3M
16.
The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1
Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang
Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8
PMCID:
PMC9022944
AbstractArticlePDF–8.9M
17.
HTLV-1 activates YAP via NF-κB/p65 to promote oncogenesis
Tiejun Zhao, Zhilong Wang, Jinyong Fang, Wenzhao Cheng, Yiling Zhang, Jinhua Huang, Lingling Xu, Hongwei Gou, Linghui Zeng, Zhigang Jin, Masao Matsuoka
Proc Natl Acad Sci U S A. 2022 Mar 1; 119(9): e2115316119. Published online 2022 Feb 24. doi: 10.1073/pnas.2115316119
PMCID:
PMC8892356
AbstractArticlePDF–1.4M
18.
The E3 ubiquitin ligase, FBXW5, promotes the migration and invasion of gastric cancer through the dysregulation of the Hippo pathway
Yangyang Yao, Zhen Liu, Shanshan Huang, Chunye Huang, Yuan Cao, Li Li, Hui Guo, Fenfen Liu, Shipeng Huang, Quan Liao, Xin He, Jun Chen, Junhe Li, Xiaojun Xiang, Jianping Xiong, Jun Deng
Cell Death Discov. 2022; 8: 79. Published online 2022 Feb 24. doi: 10.1038/s41420-022-00868-y
PMCID:
PMC8873275
AbstractArticlePDF–4.6M
19.
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway
Yu Zeng, Qin Xu, Nan Xu
Bioengineered. 2021; 12(1): 7964–7974. Published online 2021 Oct 8. doi: 10.1080/21655979.2021.1984005
PMCID:
PMC8806957
AbstractArticlePDF–1.8M
20.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M

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