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Items: 1 to 20 of 25

1.
Mrgprb2-mediated mast cell activation exacerbates Modic changes by regulating immune niches
Zhongyin Ji, Jie Li, Siyue Tao, Hui Li, Xiangxi Kong, Bao Huang, Zhenhua Feng, Xiaoan Wei, Zeyu Zheng, Jian Chen, Binhui Chen, Junhui Liu, Fengdong Zhao
Exp Mol Med. 2024 May; 56(5): 1178–1192. Published online 2024 May 1. doi: 10.1038/s12276-024-01230-1
PMCID:
PMC11148035
AbstractArticlePDF–9.9M
2.
PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice
Hyeonwi Son, Yan Zhang, John Shannonhouse, Ruben Gomez, Yu Shin Kim
J Headache Pain. 2024; 25(1): 87. Published online 2024 May 28. doi: 10.1186/s10194-024-01786-3
PMCID:
PMC11131290
AbstractArticlePDF–6.9M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
New insight into prurigo nodularis: Proadrenomedullin N‐terminal 20 peptide mediates mouse mast cell activation via Mrgprb2
Yixin Shao, Zijing Xiao, Yinghong Jin, Yiqi Zhu, Yanyun Shen, Taiyu Jin, Hui Tang, Duoqin Wang
Skin Res Technol. 2024 Feb; 30(2): e13588. Published online 2024 Jan 29. doi: 10.1111/srt.13588
PMCID:
PMC10823405
AbstractArticlePDF–2.1M
5.
Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2
Ghazl Al Hamwi, Vigneshwaran Namasivayam, Beatriz Büschbell, Robin Gedschold, Stefan Golz, Christa E. Müller
Commun Biol. 2024; 7: 52. Published online 2024 Jan 6. doi: 10.1038/s42003-023-05739-5
PMCID:
PMC10771525
AbstractArticlePDF–3.0M
6.
PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain
Sami Sbei, Taylor Moncrief, Nathachit Limjunyawong, Yaping Zeng, Dustin P. Green
Sci Rep. 2023; 13: 12302. Published online 2023 Jul 29. doi: 10.1038/s41598-023-39571-y
Correction in:
Sci Rep. 2023; 13: 13298.
PMCID:
PMC10387048
AbstractArticlePDF–2.8M
7.
Colitis aggravated by Mrgprb2 knockout is associated with altered immune response, intestinal barrier function and gut microbiota
Ming Shao, Jingwen Liu, Hesheng Luo
Exp Physiol. 2023 Jan; 108(1): 63–75. Published online 2022 Nov 28. doi: 10.1113/EP090635
PMCID:
PMC10103767
AbstractArticlePDF–6.7M
8.
GRK2 differentially regulates FcεRI and MRGPRB2-mediated responses in mast cells
Monica Thapaliya, Hydar Ali
Front Immunol. 2023; 14: 1155777. Published online 2023 Mar 29. doi: 10.3389/fimmu.2023.1155777
PMCID:
PMC10090543
AbstractArticlePDF–4.7M
9.
Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by β-Arrestin 2
Saptarshi Roy, Ibrahim Alkanfari, Shaswati Chaki, Hydar Ali
J Invest Dermatol. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: J Invest Dermatol. 2022 Nov; 142(11): 2988–2997.e3. Published online 2022 May 26. doi: 10.1016/j.jid.2022.05.005
PMCID:
PMC9634617
AbstractArticlePDF–1.7M
10.
P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice
Kazuki Yoshida, Shota Tanihara, Yuki Miyashita, Kosuke Obayashi, Masa-aki Ito, Kimiko Yamamoto, Toshiyashu Imai, Isao Matsuoka
Sci Rep. 2022; 12: 18613. Published online 2022 Nov 3. doi: 10.1038/s41598-022-21667-6
PMCID:
PMC9633816
AbstractArticlePDF–1.5M
11.
GRK2 inhibitors, paroxetine and CCG258747, attenuate IgE-mediated anaphylaxis but activate mast cells via MRGPRX2 and MRGPRB2
Monica Thapaliya, Aetas Amponnawarat, John J. G. Tesmer, Hydar Ali
Front Immunol. 2022; 13: 1032497. Published online 2022 Oct 6. doi: 10.3389/fimmu.2022.1032497
PMCID:
PMC9583242
AbstractArticlePDF–3.2M
12.
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis
Shiqun Zhang, Tara N. Edwards, Virendra K. Chaudhri, Jianing Wu, Jonathan A. Cohen, Toshiro Hirai, Natalie Rittenhouse, Elizabeth G. Schmitz, Paul Yifan Zhou, Benjamin D. McNeil, Yi Yang, H. Richard Koerber, Tina L. Sumpter, Amanda C. Poholek, Brian M. Davis, Kathryn M. Albers, Harinder Singh, Daniel H. Kaplan
Cell. Author manuscript; available in PMC 2022 Apr 15.
Published in final edited form as: Cell. 2021 Mar 18 : S0092-8674(21)00287-7. Published online 2021 Mar 18. doi: 10.1016/j.cell.2021.03.002
PMCID:
PMC8052305
AbstractArticlePDF–1.2M
13.
House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation
Nadine Serhan, Lilian Basso, Riccardo Sibilano, Camille Petitfils, James Meixiong, Chrystelle Bonnart, Laurent L. Reber, Thomas Marichal, Philipp Starkl, Nicolas Cenac, Xinzhong Dong, Mindy Tsai, Stephen J. Galli, Nicolas Gaudenzio
Nat Immunol. Author manuscript; available in PMC 2020 Apr 7.
Published in final edited form as: Nat Immunol. 2019 Nov; 20(11): 1435–1443. Published online 2019 Oct 7. doi: 10.1038/s41590-019-0493-z
PMCID:
PMC6858877
AbstractArticlePDF–2.1M
14.
A Connective Tissue Mast Cell-Specific Receptor Detects Bacterial Quorum Sensing Molecules and Mediates Antibacterial Immunity
Priyanka Pundir, Rui Liu, Chirag Vasavda, Nadine Serhan, Nathachit Limjunyawong, Rebecca Yee, Yingzhuan Zhan, Xintong Dong, Xueqing Wu, Ying Zhang, Solomon H. Snyder, Nicolas Gaudenzio, Jorge E. Vidal, Xinzhong Dong
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 114–122.e8. Published online 2019 Jul 2. doi: 10.1016/j.chom.2019.06.003
PMCID:
PMC6649664
AbstractArticlePDF–1.5M
15.
Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch
James Meixiong, Michael Anderson, Nathachit Limjunyawong, Mark F. Sabbagh, Eric Hu, Madison R. Mack, Landon K. Oetjen, Fang Wang, Brian S. Kim, Xinzhong Dong
Immunity. Author manuscript; available in PMC 2020 May 21.
Published in final edited form as: Immunity. 2019 May 21; 50(5): 1163–1171.e5. Published online 2019 Apr 23. doi: 10.1016/j.immuni.2019.03.013
PMCID:
PMC6531358
AbstractArticlePDF–1.6M
16.
Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs
Ibrahim Alkanfari, Katie B. Freeman, Saptarshi Roy, Tahsin Jahan, Richard W. Scott, Hydar Ali
Cells. 2019 Apr; 8(4): 311. Published online 2019 Apr 3. doi: 10.3390/cells8040311
PMCID:
PMC6523814
AbstractArticlePDF–1.9M
17.
A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain
Dustin P. Green, Nathachit Limjunyawong, Naina Gour, Priyanka Pundir, Xinzhong Dong
Neuron. Author manuscript; available in PMC 2020 Feb 6.
Published in final edited form as: Neuron. 2019 Feb 6; 101(3): 412–420.e3. Published online 2019 Jan 24. doi: 10.1016/j.neuron.2019.01.012
PMCID:
PMC6462816
AbstractArticlePDF–1.6M
18.
Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors
Shalini Jain, Anna Panyutin, Naili Liu, Cuiying Xiao, Ramón A. Piñol, Priyanka Pundir, Clémence Girardet, Andrew A. Butler, Xinzhong Dong, Oksana Gavrilova, Marc L. Reitman
Am J Physiol Endocrinol Metab. 2018 Sep 1; 315(3): E357–E366. Published online 2018 May 29. doi: 10.1152/ajpendo.00024.2018
PMCID:
PMC6171009
AbstractArticle
19.
Different activation signals induce distinct mast cell degranulation strategies
Nicolas Gaudenzio, Riccardo Sibilano, Thomas Marichal, Philipp Starkl, Laurent L. Reber, Nicolas Cenac, Benjamin D. McNeil, Xinzhong Dong, Joseph D. Hernandez, Ronit Sagi-Eisenberg, Ilan Hammel, Axel Roers, Salvatore Valitutti, Mindy Tsai, Eric Espinosa, Stephen J. Galli
J Clin Invest. 2016 Oct 3; 126(10): 3981–3998. Published online 2016 Sep 19. doi: 10.1172/JCI85538
PMCID:
PMC5096814
AbstractArticlePDF–6.9M
20.
Identification of a mast cell specific receptor crucial for pseudo-allergic drug reactions
Benjamin D. McNeil, Priyanka Pundir, Sonya Meeker, Liang Han, Bradley J. Undem, Marianna Kulka, Xinzhong Dong
Nature. Author manuscript; available in PMC 2015 Sep 12.
Published in final edited form as: Nature. 2015 Mar 12; 519(7542): 237–241. Published online 2014 Dec 17. doi: 10.1038/nature14022
PMCID:
PMC4359082
AbstractArticlePDF–3.5M

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