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Select item 110093901.

Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer

Jie Fu, Jianhua Ling, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, Junwei Hou, Ping Chen, Yu Cao, Ya’an Kang, Yichen Sun, Xianghou Xia, Zhou Jiang, Kenei Furukawa, Yu Lu, Min Wu, Qian Huang, Jun Yao, David H. Hawke, Bih-Fang Pan, Jun Zhao, Jiaxing Huang, Huamin Wang, E. I. Mustapha Bahassi, Peter J. Stambrook, Peng Huang, Jason B. Fleming, Anirban Maitra, John A. Tainer, Mien-Chie Hung, Chunru Lin, Paul J. Chiao

Nat Commun. 2024; 15: 3149. Published online 2024 Apr 11. doi: 10.1038/s41467-024-47242-3

PMCID:: PMC11009390

Abstract Article PDF–8.5M

Select item 92495062.

Inhibition of PLK3 Attenuates Tubular Epithelial Cell Apoptosis after Renal Ischemia–Reperfusion Injury by Blocking the ATM/P53-Mediated DNA Damage Response

Weiming Deng, Xiangling Wei, Zhenwei Xie, Rui Zhang, Zhanwen Dong, Jinhua Zhang, You Luo, Qingdi Cheng, Ruojiao Wang, Heng Li, Ning Na

Oxid Med Cell Longev. 2022; 2022: 4201287. Published online 2022 Jun 24. doi: 10.1155/2022/4201287

PMCID:: PMC9249506

Abstract Article PDF–5.0M

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 78467734.

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3

Catherine A. Vaughan, Shilpa Singh, Mark A. Subler, Jolene J. Windle, Kazushi Inoue, Elizabeth A. Fry, Raghavendra Pillappa, Steven R. Grossman, Brad Windle, W. Andrew Yeudall, Swati Palit Deb, Sumitra Deb

Nat Commun. 2021; 12: 704. Published online 2021 Jan 29. doi: 10.1038/s41467-021-20928-8

PMCID:: PMC7846773

Abstract Article PDF–3.1M

Select item 76695625.

Keratin 13 Deficiency Causes White Sponge Nevus in Mice

Laura Simonson, Samantha Vold, Colton Mowers, Randall J Massey, Irene M Ong, B. Jack Longley, Hao Chang

Dev Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Dev Biol. 2020 Dec 1; 468(1-2): 146–153. Published online 2020 Aug 3. doi: 10.1016/j.ydbio.2020.07.016

PMCID:: PMC7669562

Abstract Article PDF–2.2M

Select item 73643846.

Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors

David L. Myer, Susan B. Robbins, Moying Yin, Gregory P. Boivin, Yang Liu, Kenneth D. Greis, El Mustapha Bahassi, Peter J. Stambrook

Mutat Res. Author manuscript; available in PMC 2020 Jul 16.

Published in final edited form as: Mutat Res. 2011 Sep 1; 714(1-2): 1–10. Published online 2011 Mar 3. doi: 10.1016/j.mrfmmm.2011.02.006

PMCID:: PMC7364384

Abstract Article PDF–1.4M

Select item 47808217.

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression

Jillian J. Goetz, Lauren A. Laboissonniere, Andrea K. Wester, Madison R. Lynch, Jeffrey M. Trimarchi

PLoS One. 2016; 11(3): e0150878. Published online 2016 Mar 7. doi: 10.1371/journal.pone.0150878

PMCID:: PMC4780821

Abstract Article PDF–30M

Select item 42079958.

Osmotic Stress-induced Phosphorylation of H2AX by Polo-like Kinase 3 Affects Cell Cycle Progression in Human Corneal Epithelial Cells

Ling Wang, Wei Dai, Luo Lu

J Biol Chem. 2014 Oct 24; 289(43): 29827–29835. Published online 2014 Sep 8. doi: 10.1074/jbc.M114.597161

PMCID:: PMC4207995

Abstract Article PDF–1.5M

Select item 41789669.

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1

Olivia Barton, Steffen C. Naumann, Ronja Diemer-Biehs, Julia Künzel, Monika Steinlage, Sandro Conrad, Nodar Makharashvili, Jiadong Wang, Lin Feng, Bernard S. Lopez, Tanya T. Paull, Junjie Chen, Penny A. Jeggo, Markus Löbrich

J Cell Biol. 2014 Sep 29; 206(7): 877–894. doi: 10.1083/jcb.201401146

PMCID:: PMC4178966

Abstract Article PDF–3.5M

Select item 398712010.

Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore

eLife. 2014; 3: e01694. Published online 2014 Apr 15. doi: 10.7554/eLife.01694

Correction in:: eLife. 2015; 4: e10084.

PMCID:: PMC3987120

Abstract Article PDF–3.9M

Select item 375379911.

Genomic Strategy Identifies a Missense Mutation in WD-Repeat Domain 65 (WDR65) in an Individual with Van der Woude Syndrome

Nicholas K. Rorick, Akira Kinoshita, Jason Weirather, Myriam Peyrard-Janvid, Renata L. L. Ferreira de Lima, Martine Dunnwald, Alan L. Shanske, Danilo Moretti-Ferreira, Hannele Koillinen, Juha Kere, Maria A. Mansilla, Jeffrey C. Murray, Steve L. Goudy, Brian C. Schutte

Am J Med Genet A. Author manuscript; available in PMC 2013 Aug 27.

Published in final edited form as: Am J Med Genet A. 2011 Jun; 0(6): 1314–1321. Published online 2011 May 13. doi: 10.1002/ajmg.a.33980

PMCID:: PMC3753799

Abstract Article PDF–742K

Select item 372559112.

Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1α under Hypoxic Conditions

Yali Yang, Jingxiang Bai, Rulong Shen, Sharron A.N. Brown, Elena Komissarova, Ying Huang, Ning Jiang, Gregory F. Alberts, Max Costa, Luo Lu, Jeffrey A. Winkles, Wei Dai

Cancer Res. Author manuscript; available in PMC 2013 Jul 29.

Published in final edited form as: Cancer Res. 2008 Jun 1; 68(11): 4077–4085. doi: 10.1158/0008-5472.CAN-07-6182

PMCID:: PMC3725591

Abstract Article PDF–4.3M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163