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Select item 110631601.

Large-language models facilitate discovery of the molecular signatures regulating sleep and activity

Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang

Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w

PMCID:: PMC11063160

Abstract Article PDF–2.7M

Select item 107198522.

Opposing roles of Fos, Raw, and SARM1 in the regulation of axonal degeneration and synaptic structure

Thomas J. Waller, Catherine A. Collins

Front Cell Neurosci. 2023; 17: 1283995. Published online 2023 Nov 30. doi: 10.3389/fncel.2023.1283995

PMCID:: PMC10719852

Abstract Article PDF–4.5M

Select item 104425443.

A nerve-wracking buzz: lessons from Drosophila models of peripheral neuropathy and axon degeneration

Martha R. C. Bhattacharya

Front Aging Neurosci. 2023; 15: 1166146. Published online 2023 Aug 8. doi: 10.3389/fnagi.2023.1166146

PMCID:: PMC10442544

Abstract Article PDF–841K

Select item 103724084.

Dissecting morphogenetic apoptosis through a genetic screen in Drosophila

Audrey Barbaste, Sonia Schott, Corinne Benassayag, Magali Suzanne

Life Sci Alliance. 2023 Oct; 6(10): e202301967. Published online 2023 Jul 26. doi: 10.26508/lsa.202301967

PMCID:: PMC10372408

Abstract Article PDF–4.5M

Select item 103323245.

The identification of protein and RNA interactors of the splicing factor Caper in the adult Drosophila nervous system

M. Brandon Titus, Adeline W. Chang, Niko Popitsch, Christopher C. Ebmeier, Jeremy M. Bono, Eugenia C. Olesnicky

Front Mol Neurosci. 2023; 16: 1114857. Published online 2023 Jun 23. doi: 10.3389/fnmol.2023.1114857

PMCID:: PMC10332324

Abstract Article PDF–4.5M

Select item 102682426.

The Drosophila chemokine–like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons

Hui Ji, Bei Wang, Yifan Shen, David Labib, Joyce Lei, Xinchen Chen, Maria Sapar, Ana Boulanger, Jean-Maurice Dura, Chun Han

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2303392120. Published online 2023 Jun 5. doi: 10.1073/pnas.2303392120

PMCID:: PMC10268242

Abstract Article PDF–13M

Select item 100741087.

Reverse electron transfer is activated during aging and contributes to aging and age‐related disease

Suman Rimal, Ishaq Tantray, Yu Li, Tejinder Pal Khaket, Yanping Li, Sunil Bhurtel, Wen Li, Cici Zeng, Bingwei Lu

EMBO Rep. 2023 Apr; 24(4): e55548. Published online 2023 Feb 16. doi: 10.15252/embr.202255548

PMCID:: PMC10074108

Abstract Article PDF–3.9M

Select item 99304368.

Identification of potential pathways and biomarkers linked to progression in ALS

Roland G. Huber, Swapnil Pandey, Deepak Chhangani, Diego E. Rincon‐Limas, Nathan P. Staff, Crystal Jing Jing Yeo

Ann Clin Transl Neurol. 2023 Feb; 10(2): 150–165. Published online 2022 Dec 19. doi: 10.1002/acn3.51697

PMCID:: PMC9930436

Abstract Article PDF–2.5M

Select item 97888119.

The NAD⁺ precursor NMN activates dSarm to trigger axon degeneration in Drosophila

Arnau Llobet Rosell, Maria Paglione, Jonathan Gilley, Magdalena Kocia, Giulia Perillo, Massimiliano Gasparrini, Lucia Cialabrini, Nadia Raffaelli, Carlo Angeletti, Giuseppe Orsomando, Pei-Hsuan Wu, Michael P Coleman, Andrea Loreto, Lukas Jakob Neukomm

eLife. 2022; 11: e80245. Published online 2022 Dec 23. doi: 10.7554/eLife.80245

PMCID:: PMC9788811

Abstract Article PDF–8.4M

Select item 950700010.

Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Meng Ding, Hongyu Li, Lan Zheng

Front Cell Dev Biol. 2022; 10: 966531. Published online 2022 Sep 9. doi: 10.3389/fcell.2022.966531

PMCID:: PMC9507000

Abstract Article PDF–1.2M

Select item 930462911.

Cellular Pathogenesis of Chemotherapy-Induced Peripheral Neuropathy: Insights From Drosophila and Human-Engineered Skin Models

Grace Ji-eun Shin, Hasan Erbil Abaci, Madison Christine Smith

Front Pain Res (Lausanne) 2022; 3: 912977. Published online 2022 Jul 8. doi: 10.3389/fpain.2022.912977

PMCID:: PMC9304629

Abstract Article PDF–393K

Select item 922331512.

Distinct developmental and degenerative functions of SARM1 require NAD⁺ hydrolase activity

E. J. Brace, Kow Essuman, Xianrong Mao, John Palucki, Yo Sasaki, Jeff Milbrandt, Aaron DiAntonio

PLoS Genet. 2022 Jun; 18(6): e1010246. Published online 2022 Jun 23. doi: 10.1371/journal.pgen.1010246

PMCID:: PMC9223315

Abstract Article PDF–2.9M

Select item 901851513.

The putative Drosophila TMEM184B ortholog Tmep ensures proper locomotion by restraining ectopic firing at the neuromuscular junction

Tiffany S. Cho, Eglė Beigaitė, Nathaniel E. Klein, Sean T. Sweeney, Martha R.C. Bhattacharya

Mol Neurobiol. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Mol Neurobiol. 2022 Apr; 59(4): 2605–2619. Published online 2022 Feb 2. doi: 10.1007/s12035-022-02760-3

PMCID:: PMC9018515

Abstract Article PDF–1.9M

Select item 898803514.

Human Nmnat1 Promotes Autophagic Clearance of Amyloid Plaques in a Drosophila Model of Alzheimer’s Disease

Yi Zhu, Amanda G. Lobato, R. Grace Zhai, Milena Pinto

Front Aging Neurosci. 2022; 14: 852972. Published online 2022 Mar 24. doi: 10.3389/fnagi.2022.852972

PMCID:: PMC8988035

Abstract Article PDF–1.2M

Select item 879552815.

Phagocytosis and self-destruction break down dendrites of Drosophila sensory neurons at distinct steps of Wallerian degeneration

Hui Ji, Maria L. Sapar, Ankita Sarkar, Bei Wang, Chun Han

Proc Natl Acad Sci U S A. 2022 Jan 25; 119(4): e2111818119. Published online 2022 Jan 20. doi: 10.1073/pnas.2111818119

Correction in:: Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2204683119.

PMCID:: PMC8795528

Abstract Article PDF–4.4M

Select item 868308616.

NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis

Jiaqi Liu, Xianzun Tao, Yi Zhu, Chong Li, Kai Ruan, Zoraida Diaz-Perez, Priyamvada Rai, Hongbo Wang, R Grace Zhai

eLife. 2021; 10: e70046. Published online 2021 Dec 17. doi: 10.7554/eLife.70046

PMCID:: PMC8683086

Abstract Article PDF–30M

Select item 866448617.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 804404218.

Synaptic homeostats: latent plasticity revealed at the Drosophila neuromuscular junction

Pragya Goel, Dion Dickman

Cell Mol Life Sci. 2021 Apr; 78(7): 3159–3179. Published online 2021 Jan 15. doi: 10.1007/s00018-020-03732-3

PMCID:: PMC8044042

Abstract Article PDF–1.7M

Select item 786487819.

Injury-induced inhibition of bystander neurons requires dSarm and signaling from glia

Jiun-Min Hsu, Yunsik Kang, Megan M. Corty, Danielle Mathieson, Owen M. Peters, Marc Freeman

Neuron. Author manuscript; available in PMC 2022 Feb 3.

Published in final edited form as: Neuron. 2021 Feb 3; 109(3): 473–487.e5. Published online 2020 Dec 8. doi: 10.1016/j.neuron.2020.11.012

PMCID:: PMC7864878

Abstract Article PDF–1.4M

Select item 713602620.

Nicotinamide mononucleotide adenylyltransferase uses its NAD⁺ substrate-binding site to chaperone phosphorylated Tau

Xiaojuan Ma, Yi Zhu, Jinxia Lu, Jingfei Xie, Chong Li, Woo Shik Shin, Jiali Qiang, Jiaqi Liu, Shuai Dou, Yi Xiao, Chuchu Wang, Chunyu Jia, Houfang Long, Juntao Yang, Yanshan Fang, Lin Jiang, Yaoyang Zhang, Shengnan Zhang, Rong Grace Zhai, Cong Liu, Dan Li

eLife. 2020; 9: e51859. Published online 2020 Apr 6. doi: 10.7554/eLife.51859